As birras das crianças: o papel do educador e dos encarregados de educação

Relatório da Prática Profissional Supervisionada Mestrado em Educação Pré-Escolar

B-1 cells temper endotoxemic inflammatory responses

Sepsis syndrome is caused by inappropriate immune activation due to bacteria and bacterial components released during infection. This syndrome is the leading cause of death in intensive care units. Specialized B-lymphocytes located in the peritoneal and pleural cavities are known as B-1 cells. These cells produce IgM and IL-10, both of which are potent regulators of cell-mediated immunity. It has been suggested that B-1 cells modulate the systemic inflammatory response in sepsis. In this study, we conducted in vitro and in vivo experiments in order to investigate a putative role of B-1 cells in a murine model of LPS-induced sepsis. Macrophages and B-1 cells were studied in monocultures and in co-cultures. The B-1 cells produced the anti-inflammatory cytokine IL-10 in response to LPS. In the B-1 cell-macrophage co-cultures, production of proinflammatory mediators (TNF-alpha, IL-6 and nitrite) was lower than in the macrophage monocultures, whereas that of IL-10 was higher in the co-cultures. Co-culture of B-1 IL-10(-/-) cells and macrophages did not reduce the production of the proinflammatory mediators (TNF-alpha, IL-6 and nitrite). After LPS injection, the mortality rate was higher among Balb/Xid mice, which are B-1 cell deficient, than among wild-type mice (65.0% vs. 0.0%). The Balb/Xid mice also presented a proinflammatory profile of TNF-alpha, IL-6 and nitrite, as well as lower levels of IL-10. In the early phase of LPS stimulation, B-1 cells modulate the macrophage inflammatory response, and the main molecular pathway of that modulation is based on IL-10-mediated intracellular signaling. (C) 2010 Elsevier GmbH. All rights reserved.

Temper and Temperature: The Missing Link of Climate on Armed Conflicts

We investigate the causes of a conflict by adding ambient climate factors to the existing bundle of most significant variables. It turns out that – controlling for possible associations – temperature could actually induce a conflict. We emphasise that temperature could not be a dominant reason in starting a conflict; however, it could escalate the chances when other factors are present. This paper references some of the related psychological studies to support this claim. We also show that grievance factors could actually be rightfully effective in starting an internal conflict alongside greed based reasons. In the end, we believe that it could be informative to study ambient factors more often in economics.

Atención temperá : núcleos fundamentais para a intervención. 'Atención temprana : núcleos fundamentales para la intervención'.

Se presenta una breve descripción histórica de los núcleos temáticos que fueron configurando el currículo de la educación infantil, junto con las bases teóricas y legislativas que sirvieron para fundamentar y desenvolver los diferentes instrumentos y agentes de intervención que conforman la Atención Temprana, a través de sus diferentes etapas y subetapas, con referencia especial al modelo desarrollado en Cataluña.

Crecemento e desenvolvemento, pubertade temperá e tardía : repercusión biopsicosocial : alertas, estratexias de intervención. 'Crecimiento y desarrollo, pubertad temprana y tardía : repercusión biopsicosocial : alertas, estrategias de intervención'.

Resumen basado en el de la publicación

Orientation dependence of stored energy of cold work in semi-processed electrical steels after temper rolling

Microhardness measurements were carried out in a low carbon lamination steel after 6% of temper rolling, in order to evaluate local variations of work hardening as a function of crystallographic orientation. EBSD (electron back scattered diffraction) was used to determine grain orientations with respect to individual rolling planes and rolling directions. Hardness was shown to increase with the local Taylor factor. TEM observations and a well-known dislocation hardening model were used to confirm the equivalence between hardness values and the stored energy of cold work. A definite correlation between stored energy and Taylor factors could therefore be established, being more consistent than previous data reported in the literature. The improvement was thought to be related to the rather small plastic deformation, during which Taylor factors could be considered to remain constant. (c) 2006 Elsevier B.V. All rights reserved.

Effects of cryogenic and stress relief treatments on temper carbide precipitation in AISI D2 tool steel

The effects of cryogenic and stress relief treatments on temper carbide precipitation in the cold work tool steel AISI D2 were studied. For the cryogenic treatment the temperature was −196°C and the holding time was 2, 24 or 30 h. The stress relief heat treatment was carried at 130°C/90 min, when applied. All specimens were compared to a standard thermal cycle. Specimens were studied using metallographic characterisation, X-ray diffraction and thermoelectric power measurements. The metallographic characterisation used SEM (scanning electron microscopy) and SEM-FEG (SEM with field emission gun), besides OM (optical microscopy). No variation in the secondary carbides (micrometre sized) precipitation was found. The temper secondary carbides (nanosized) were found to be more finely dispersed in the matrix of the specimens with cryogenic treatment and without stress relief. The refinement of the temper secondary carbides was attributed to a possible in situ carbide precipitation during tempering.

Remarks on the influence of climate, situation, nature of country ... on the disposition and temper, manners and behaviour ... of mankind /

Mode of access: Internet.

Astronomical principles of religion, natural and reveald : in nine parts ... : together with a preface, of the Temper of mind necessary for the discovery of Divine truth, and of the Degree of evidence that ought to be expectes in Divine Matters /

Mode of access: Internet.

Theologia eklektikē : A discourse of the liberty of prophesying, with its just limits and temper : shewing the unreasonableness of prescribing to other men's faith, and the iniquity of persecuting differing opinions /

Mode of access: Internet.

Causal power in regeneration proper, directed upon the mind and not exerted through the medium of motives : argued upon the principles of the exercise system, though the author believes in a temper or nature anterior to exercise /

Mode of access: Internet.

Christian charity explained : or, The influence of religion upon temper stated; in an exposition of the thirteenth chapter of the First Epistle to the Corinthians /

Mode of access: Internet.

The present state of Great-Britain and Ireland. : In three parts. The I. Of South II. Of North Britain. III. Of Ireland. Containing an accurate and impartial account of these great and famous islands: of their several counties, and their inhabitants; the advantages and disadvantages of both, in respect to foreign countries; and their curiosities both of nature and art. Of... London... and of the famous universities... Of the Britains original, language, temper, genius, religion, morals, trade, &c. Their nobility, gentry, clergy, and commonalty. Their laws and government; with a succinct history of all the English monarchs... With the lists of the present officers in church and state, of... Parliament, and of the Convocation. To which is added a map of the three kingdoms. Also the present state of His Majesty's dominions in Germany... and a new map of them all.

In MS on t-p & elsewhere: Willm Pawley 1758[?]; Judith Buch 1735; fore edge label: New state of Engl.

The liberty of prophesying, with its just limits and temper considered with reference to the circumstances of the modern church; Lyman Beecher lectures delivered 1909, before the Yale Divinity School, and three sermons

Mode of access: Internet.