Memoir of Mrs. Sarah Lanman Smith ... /

Mode of access: Internet.

Memoir of Mrs. Sarah Lanman Smith ... /

Mode of access: Internet.

Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion.

Spectroscopic and Catalytic Characterization of a Functional (FeFeII)-Fe-III Biomimetic for the Active Site of Uteroferrin and Protein Cleavage

A mixed-valence complex, [Fe(III)Fe(II)L1(mu-OAc)(2)]BF4 center dot H2O, where the ligand H(2)L1 = 2-{[[3-[((bis-(pyridin-2-ylmethyl)amino)methyl)-2-hydroxy-5-methylbenzyl](pyridin-2-ylmethyl)amino]methyl]phenol}, has been studied with a range of techniques, and, where possible, its properties have been compared to those of the corresponding enzyme system purple acid phosphatase. The (FeFeII)-Fe-III and Fe-2(III) oxidized species were studied spectroelectrochemically. The temperature-dependent population of the S = 3/2 spin states of the heterovalent system, observed using magnetic circular dichroism, confirmed that the dinuclear center is weakly antiferromagnetically coupled (H = -2JS(1).S-2, where J = -5.6 cm(-1)) in a frozen solution. The ligand-to-metal charge-transfer transitions are correlated with density functional theory calculations. The (FeFeII)-Fe-III complex is electron paramagnetic resonance (EPR)-silent, except at very low temperatures (<2 K), because of the broadening caused by the exchange coupling and zero-field-splitting parameters being of comparable magnitude and rapid spin-lattice relaxation. However, a phosphate-bound Fe-2(III) complex showed an EPR spectrum due to population of the S-tot = 3 state (J= -3.5 cm(-1)). The phosphatase activity of the (FeFeII)-Fe-III complex in hydrolysis of bis(2,4-dinitrophenyl)phosphate (k(cat.) = 1.88 x 10(-3) s(-1); K-m = 4.63 x 10(-3) mol L-1) is similar to that of other bimetallic heterovalent complexes with the same ligand. Analysis of the kinetic data supports a mechanism where the initiating nucleophile in the phosphatase reaction is a hydroxide, terminally bound to Fe-III. It is interesting to note that aqueous solutions of [Fe(III)Fe(II)L1(mu-OAc)(2)](+) are also capable of protein cleavage, at mild temperature and pH conditions, thus further expanding the scope of this complex's catalytic promiscuity.

1984/1985 UM Women's Basketball Team

Back Row: head coach Bud Van De Wege, ass't coach Debbie Norman, ass't coach Andrea Wickerham, Melanie Smith, Sarah Basford, Shawne Brow, Cookie Henry, Orethia Lilly, Kelly Benintendi, manger Kara Swanson, manager Maria Andros, trainer Karla Hench

Front Row: Lorea Feldman, Wendy Bradetich, Amy Rembisz, Diana Wiley, Connie Doutt, Connie Tudor, Sandy Svoboda, Jerene Middleton

Adobe days; being the truthful narrative of the events in the life of a California girl on a sheep ranch and in El pueblo de Nuestra Señora de los Angeles while it was yet a small and humble town; together with an account of how three young men from Maine in eighteen hundred and fifty-three drove sheep and cattle across the plains, mountains and deserts from Illinois to the Pacific coast; and the strange prophecy of Admiral Thatcher about San Pedro harbor,

Mode of access: Internet.

De mutata sub primis Caesaribus eloquentiae romanae condicione, imprimis de rhetorum scholis, commentatio historica.

Programm - Berlinisches Gymnasium zum grauen Kloster, Berlin.

Opere scelte /

Mode of access: Internet.

Speech of John Thompson Brown (of Petersburg,) in the House of Delegates of Virginia, in Committee of the Whole, on the state of the relations between the United States and South Carolina.

Mode of access: Internet.

Sacred biography, or, The history of the patriarchs : to which is added, the history of Deborah, Ruth, and Hannah, and also the history of Jesus Christ : being a course of lectures delivered at the Scotch Church, London-Wall / c by Henry Hunter.

In double columns.

Expositions on the creed, the Lord's Prayer, and the Ten Commandments; with two discourses. To which are added Expository lectures on Psalm xxxix.

Mode of access: Internet.

History of the Peloponnesian war.

Mode of access: Internet.

Practical and mental arithmetic, on a new plan, in which mental arithmetic is combined with the use of the slate ...

Mode of access: Internet.

Are branched chain fatty acids the natural substrates for P450(BM3)?

Branched chain fatty acids are substrates for cytochrome P450(BM3) (CYP102) from Bacillus megaterium; oxidation of C-15 and C-17 iso and anteiso fatty acids by P450(BM3) leads to the formation of hydroxylated products that possess high levels of regiochemical and stereochemical purity.