Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing


Autoria(s): Cook, Michael T.; Smith, Sarah L.; Khutoryanskiy, Vitaliy V.
Data(s)

21/07/2015

Resumo

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion.

Formato

text

Identificador

http://centaur.reading.ac.uk/42544/1/Mucosa-mimetic%20gels-ChemComm%20%282015%29.pdf

Cook, M. T. <http://centaur.reading.ac.uk/view/creators/90004919.html>, Smith, S. L. and Khutoryanskiy, V. V. <http://centaur.reading.ac.uk/view/creators/90000952.html> (2015) Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing. Chemical Communications, 51 (77). pp. 14447-14450. ISSN 1359-7345 doi: 10.1039/C5CC02428E <http://dx.doi.org/10.1039/C5CC02428E>

Idioma(s)

en

Publicador

The Royal Society of Chemistry

Relação

http://centaur.reading.ac.uk/42544/

creatorInternal Cook, Michael T.

creatorInternal Khutoryanskiy, Vitaliy V.

http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/c5cc02428e#!divAbstract

10.1039/C5CC02428E

Direitos

cc_by

Tipo

Article

PeerReviewed