1000 resultados para Sin, Original.


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Booksellers' advertisement, p. [31-32].

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En el presente artículo revisamos el trabajo etnográfico que un misionero franciscano del siglo XVI, fray Jerónimo de Alcalá, realizó por medio de la traducción. Su principal obra, la Relación de Michoacán, constituye uno de los más valiosos manuscritos coloniales de toda América. Para su elaboración recopiló, tradujo y fijó en el papel la tradición oral purépecha, rescatando del olvido el testimonio histórico y antropológico de la riqueza cultural michoacana. El rigor científico de su trabajo de campo, que acometió humildemente como “fiel intérprete” y con mera intención misional, ha hecho de su obra una fuente documental imprescindible.

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Bibliography: p. 353-356.

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Bibliography: v.l, p. 377-384; v.2, p. 574-580.

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Mode of access: Internet.

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Written in response to Taylor's Concio ad clerum. A sermon delivered in the chapel of Yale College, September 10, 1828. ...

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Mode of access: Internet.

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Cover imprint: 1847.

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The Apologia, originally published separately in 1547, has caption title: Apologia qua ... Ambrosio Catharino, episcopo Minoriensi, de certitudine gratiae respondet.

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Original antigenic sin is failure to mount effective immunity to virus variants in a previously virus infected host. We have previously shown that prior immunity to a virus capsid protein inhibits induction from naive CD8 T cells of an IFN-g response to a MHC class I restricted epitope linked to the capsid protein, following immunisation with a capsid expressing the class I restricted epitope. The inhibition is independent of pre-existing antibody to the viral capsid, and the inhibition is observed in animal lacking B cells. CD8 restricted viral capsid specific T cell responses are also not required, but the inhibition is not observed in IL10 knockout mice. We now demonstrate that capsid antigen primed CD4+ T cells secrete IL10 in response to capsid antigen presented by DC, and deviate CD8 cells specific for the linked MHC Class I restricted epitope from IFN-g production to IL-5 production. Neutralizing IL10, either in vitro or in vivo, restores induction following immunisation of an antigen specific IFN-g response to an MHC Class I restricted epitope. This finding demonstrates a strategy for overcoming bias towards a Tc2 response to MHC Class I epitopes upon immunisation of a host already primed to antigen, facilitating immunotherapy for chronic viral infection or cancer

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The project of articulating a theological ethics on the basis of liturgical anthropology is bound to fail if the necessary consequence is that one has to quit the forum of critical modern rationality. The risk of Engelhardt's approach is to limit rationality to a narrow vision of reason. Sin is not to be understood as the negation of human holiness, but as the negation of divine holiness. The only way to renew theological ethics is to understand sin as the anthropological and ethical expression of the biblical message of the justification by faith only. Sin is therefore a secondary category, which can only by interpreted in light of the positive manifestation of liberation, justification, and grace. The central issue of Christian ethics is not ritual purity or morality, but experience, confession and recognition of our own injustice in our dealing with God and men.

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In the real world, mice and men are not immunologically naive, having been exposed to numerous antigenic challenges. Prior infections sometimes negatively impact the response to a subsequent infection. This can occur in serial infections with pathogens sharing cross-reactive Ags. At the T cell level it has been proposed that preformed memory T cells, which cross-react with low avidity to epitopes presented in subsequent infections, dampen the response of high-avidity T cells. We investigated this with a series of related MHC class-I restricted Ags expressed by bacterial and viral pathogens. In all cases, we find that high-avidity CD8(+) T cell precursors, either naive or memory, massively expand in secondary cross-reactive infections to dominate the response over low-avidity memory T cells. This holds true even when >10% of the CD8(+) T cell compartment consists of memory T cells that cross-react weakly with the rechallenge ligand. Occasionally, memory cells generated by low-avidity stimulation in a primary infection recognize a cross-reactive epitope with high avidity and contribute positively to the response to a second infection. Taken together, our data show that the phenomenon of original antigenic sin does not occur in all heterologous infections.

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Port. con grab. xil

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"Con una constitución de Cataluña, y otro Fuero de Aragon del señor Rey don Iuan el segundo, en la misma materia."