Thermal studies on nickel(II) 4-iodopyrazole complexes

This work describes the synthesis, IR and UV-Vis spectroscopic characterization as well the thermal behavior of the [NiCl2(HIPz)(4)]center dot C3H6O (1), [Ni(H2O)(2)(HIPz)(4)](NO3)(2) (2), [Ni(NCS)(2)(HIPz)(4)] (3) and [Ni(N-3)(2)(HIPz)(4)] (4) (HIPz = 4-iodopyrazole) pyrazolyl complexes. TG experiments reveal that the compounds 1-4 undergo thermal decomposition in three or four mass loss steps yielding NiO as final residue, which was identified by X-ray powder diffraction.

Synthesis, characterization, and thermal behavior of palladium(II) complexes containing 4-iodopyrazole

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

New palladium(II) complexes with pyrazole ligands Part I. Synthesis, spectral and thermal studies, and antitumor evaluation

The pyrazole ligand 3,5-dimethyl-4-iodopyrazole (HdmIPz) has been used to obtain a series of palladium(II) complexes (1-4) of the type [PdX(2)(HdmIPz)(2)] {X = Cl(-) (1); Br(-) (2); I(-) (3); SCN(-) (4)}. All compounds have been isolated, purified, and characterized by means of elemental analysis, IR spectroscopy, (1)H and (13)C{(1)H}-NMR experiments, differential thermal analysis (DTA), and thermogravimetry (TG). The TG/DTA curves showed that the compounds released ligands in the temperature range 137-605 A degrees C, yielding metallic palladium as final residue. The complexes and the ligand together with cisplatin have been tested in vitro by MTT assay for their cytotoxicity against two murine cancer cell lines: mammary adenocarcinoma (LM3) and lung adenocarcinoma (LP07).

Synthesis, characterization, and investigation of the thermal behavior of Cu(II) pyrazolyl complexes

This work reports the synthesis, characterization, and thermal behavior of three complexes of copper (II): [CuCl(2)(HPz)(4)] (1), [CuCl(2)(HdmPz)(4)] (2), and [CuCl(2)(HIPz)(4)] (3) (HPz = pyrazole; HdmPz = 3,5-dimethylpyrazole; HIPz = 4-iodopyrazole). The compounds were characterized by elemental analysis, infrared spectroscopy, and UV-Vis measurements. The thermal study of the compounds showed that the ligands are eliminated in 2-4 stages, yielding CuO as final residue.

Investigação das potencialidades de complexos pirazólicos de Pd (II) no desenvolvimento de novas metalo-drogas

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Investigação da atividade biólogica de complexos de Cobre (II) contendo ligantes nitrogenados

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Síntese e caracterização de espécies supramoleculares de níquel(II) contendo pirazóis e pseudo-haletos com possíveis aplicações magnéticas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Hypervalent iodine in synthesis. 90. A mild and efficient method for the iodination of pyrazoles

The combined reagent of iodobenzene diacetate (or polymer-supported iodobenzene diacetate) with iodine was used as an effective iodinating agent of pyrazoles to the corresponding 4-iodopyrazole derivatives at room temperature with high yields.

A new low temperature synthesis route of fraipontite (Zn,Al)3(Si,Al)2O5(OH)4

A low temperature synthesis method based on the decomposition of urea at 90°C in water has been developed to synthesise fraipontite. This material is characterised by a basal reflection 001 at 7.44 Å. The trioctahedral nature of the fraipontite is shown by the presence of a 06l band around 1.54 Å, while a minor band around 1.51 Å indicates some cation ordering between Zn and Al resulting in Al-rich areas with a more dioctahedral nature. TEM and IR indicate that no separate kaolinite phase is present. An increase in the Al content however, did result in the formation of some SiO2 in the form of quartz. Minor impurities of carbonate salts were observed during the synthesis caused by to the formation of CO32- during the decomposition of urea.