79 resultados para Rational objective
em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"
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The objective of this study is to perform a theoretical study of the possible relationship between mathematics and art. For some people, the association between these fields of knowledge may simply seem absurd, possibly because they do not know what is in common between an area considered rigorous, rational, objective, and a more emotional, intuitive, subjective. In this context, interdisciplinarity has an important role, in proposing the contextual integration between the subject content, such as projective geometry and the renaissance. Are also presented as examples of this union, the technique of Moses and the geometric patterns of indigenous crafts, as well as the work of artist Maurits Cornelis Escher, a legitimate representative of the relationship between art and mathematics
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Background: Prescribing is a complex and challenging task that must be part of a logical deductive process based on accurate and objective information and not an automated action, without critical thinking or a response to commercial pressure. The objectives of this study were 1) develop and implement a discipline based on the WHO's Guide to Good Prescribing; 2) evaluate the course acceptance by students; 3) assess the impact that the Rational Use of Medicines (RUM) knowledge had on the students habits of prescribing medication in the University Hospital.Methods: In 2003, the RUM principal, based in the WHO's Guide to Good Prescribing, was included in the official curriculum of the Botucatu School of Medicine, Brazil, to be taught over a total of 24 hours to students in the 4th year. We analyzed the students' feedback forms about content and teaching methodology filled out immediately after the end of the discipline from 2003 to 2010. In 2010, the use of RUM by past students in their medical practice was assessed through a qualitative approach by a questionnaire with closed-ended rank scaling questions distributed at random and a single semistructured interview for content analysis.Results: The discipline teaches future prescribers to use a logical deductive process, based on accurate and objective information, to adopt strict criteria (efficacy, safety, convenience and cost) on selecting drugs and to write a complete prescription. At the end of it, most students considered the discipline very good due to the opportunity to reflect on different actions involved in the prescribing process and liked the teaching methodology. However, former students report that although they are aware of the RUM concepts they cannot regularly use this knowledge in their daily practice because they are not stimulated or even allowed to do so by neither older residents nor senior medical staff.Conclusions: This discipline is useful to teach RUM to medical students who become aware of the importance of this subject, but the assimilation of the RUM principles in the institution seems to be a long-term process which requires the involvement of a greater number of the academic members.
H-infinity control design for time-delay linear systems: a rational transfer function based approach
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Human development is associated directly or indirectly with the energy use, and because of this the energetic sources were dealt with in the recent past, as fully available to human necessities. The reality shows that the energy availability, considering the nonrenewable sources, is limited, and beyond that, the exploration, the processing and the use of energy impose considerable impacts on the environment. There is not a system which operates with no losses and without imposing changes to the environment. Therefore, the energy conservation incorporates the concepts and the actions applied to the research of sustainable balance between nature and the energy availability and use. Such actions can be presented both in the short term, in which the energy system is close to a collapse, or in the medium/long term, in which those responsible for the energy policies are concerned with the structure of the socioeconomic development. Such a situation requires more responsibility in the treatment of energy questions, mainly through education, which represents long-term investments. This paper discusses barriers that are present in the projects applied to energy conservation, by making clear that education is one of the best ways to transform the human behavior in for the rational use of energy. (C) 2003 Elsevier B.V. Ltd. All rights reserved.
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Speech signals degraded by additive noise can affects different applications in telecommunication. The noise may degrades the intelligibility of the speech signals and its waveforms as well. In some applications such as speech coding, both intelligibility and waveform quality are important but only intelligibility has been focused lastly. So, modern speech quality measurement techniques such as PESQ (Perceptual Evaluation of Speech Quality) have been used and classical distortion measurement techniques such as Cepstral Distance are becoming unused. In this paper it is shown that some classical distortion measures are still important in applications where speech corrupted by additive noise has to be evaluated.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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This work presents the application of a multiobjective evolutionary algorithm (MOEA) for optimal power flow (OPF) solution. The OPF is modeled as a constrained nonlinear optimization problem, non-convex of large-scale, with continuous and discrete variables. The violated inequality constraints are treated as objective function of the problem. This strategy allows attending the physical and operational restrictions without compromise the quality of the found solutions. The developed MOEA is based on the theory of Pareto and employs a diversity-preserving mechanism to overcome the premature convergence of algorithm and local optimal solutions. Fuzzy set theory is employed to extract the best compromises of the Pareto set. Results for the IEEE-30, RTS-96 and IEEE-354 test systems are presents to validate the efficiency of proposed model and solution technique.
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We prove that the zeros of the polynomials P.. (a) of degree m, defined by Boros and Moll via[GRAPHICS]approach the lemmiscate {zeta epsilon C: \zeta(2) - 1\ = Hzeta < 0}, as m --> infinity. (C) 2004 Elsevier B.V. All rights reserved.
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The use of medicines during pregnancy deserves special attention from dentists due to the potential risks to fetal development. The prescription of antimicrobial drugs during this period must be based not only on the etiology of the disease but also on the drug's effect on the embryo, which may be toxic, possibly leading to irreversible lesions. Interest in studies of the teratogenic effects of drugs increased in response to reports of the high incidence of phocomelia in patients treated with thalidomide. Although teratogenicity has long been known, pregnant women today are still exposed to this risk. The effects of drugs depend on the level of susceptibility of the fetus and on the period of exposure during pregnancy. In this context, and considering the paucity of studies on this subject in dentistry, the aim of this review was to offer an up-to-date compilation of data on the antimicrobial drugs most frequently used during pregnancy and the effects of their use.
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We present a class of three-dimensional integrable structures associated with the Darboux-Egoroff metric and classical Euler equations of free rotations of a rigid body. They are obtained as canonical structures of rational Landau-Ginzburg potentials and provide solutions to the Painleve VI equation.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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O trabalho é um estudo das condições de germinação das sementes de Cassia tora L., planta invasora das culturas em geral e, principalmente, da cultura da soja. Nesta pesquisa, estudou se a quebra da dormência, o efeito da profundidade de semeadura sobre a emergência de plântulas e o potencial de armazenamento, considerando o envelhecimento natural e precoce com o objetivo de um controle mais racional desta espécie. As profundidades de semeadura de 4 a 6 cm apresentaram as porcentagens mais altas de emergência das plântulas. A porcentagem de germinação de sementes, logo após a colheita, encontra-se próxima de 42%, decrescendo para 40%, 39% e 30%, aproximadamente, nos períodos de armazenamento por 90, 180 e 270 dias, respectivamente, evidenciando uma porcentagem média de germinação próxima de 38% nos períodos considerados. O processo de escarificação mecânica mostrou-se o mais eficiente para quebra da dormência das sementes
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Estudos fenológicos de longa duração em florestas tropicais são raros. Foi realizado o acompanhamento fenológico de Dipteryx odorata, no período de 1974 à 2000, em duas áreas de floresta amazônica: a Reserva Florestal Ducke (RFD) e Estação Experimental de Silvicultura Tropical (EEST). O objetivo foi observar os padrões fenológicos nas duas áreas, verificar a regularidade da floração e frutificação num período de 27 anos e a influência dos fatores climáticos nestes eventos. Foram marcados cinco indivíduos na RFD e cinco na EEST e observados quanto à produção de flores, frutos imaturos e maduros. A floração e a produção de frutos imaturos apresentaram padrão irregular nas duas áreas observadas, variando quanto a época de ocorrência e a duração entre anos e estações, mas apresentaram freqüência de ocorrência similar nos 27 anos observados. Para a fenofase frutos maduros este padrão foi diferente, com intervalos de até três anos sem ocorrência de frutos maduros, na RFD e de sete anos na EEST. Conclui-se que a freqüência de ocorrência das fenofases de floração e frutos imaturos foi anual e a de frutos maduros supra-anual, todas com padrão irregular e duração de intermediária a prolongada. Ocorreu variação de um a três anos entre episódios de floração e frutos imaturos e de um a sete anos entre episódios de frutos maduros, não ficando evidente, nesta análise, a influência dos fatores climáticos nos padrões observados. Sugere-se o uso racional dos produtos derivados de Dipteryx odorata, o cumaru, especialmente quanto à exploração de seus frutos e o desenvolvimento de mais estudos de longa duração, fundamentais para entender os padrões fenológicos reprodutivos e de oferta de recursos em florestas tropicais.
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We improve upon the method of Zhu and Zhu [A method for directly finding the denominator values of rational interpolants, J. Comput. Appl. Math. 148 (2002) 341-348] for finding the denominator values of rational interpolants, reducing considerably the number of arithmetical operations required for their computation. In a second stage, we determine the points (if existent) which can be discarded from the rational interpolation problem. Furthermore, when the interpolant has a linear denominator, we obtain a formula for the barycentric weights which is simpler than the one found by Berrut and Mittelmann [Matrices for the direct determination of the barycentric weights of rational interpolation, J. Comput. Appl. Math. 78 (1997) 355-370]. Subsequently, we give a necessary and sufficient condition for the rational interpolant to have a pole. (c) 2006 Elsevier B.V. All rights reserved.
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Objective. - In this study strains of yeasts isolated from the blood of human patients were analyzed taxonomically, their virulence factors were determined and compared, and phenotypic markers were used to compare the samples with respect to phenotypic differences across the range of patients as well as between samples isotated from the same patient.Methods. - the study involved a total of 75 strains of yeast isolated from the blood of in-patients of the Public Hospital, Botucatu, S (a) over tildeo Paulo, Brazil, with a clinical profile of fungemia. The hospital wards with the largest number of fungemias were neonatal intensive care units (ICUs) (32%) followed by gastric surgery (13.4%) and pediatric wards (10.7%). After identification, the samples were analyzed for the production of phospholipase and proteinase enzymes, and biotyped according to their susceptibility to killer toxins.Results. - the most frequent species found was Candida albicans (38.7%) followed by C. parapsilosis (30.7%). In terms of enzyme production, 98.7% of the 75 samples of yeast presented a strongly positive activity for proteinase; however, 78.7% did not present any phospholipasic activity. Six different biotypes were identified, the most frequent being 511 and 888.Conclusion. In association with phenotypic methods, genetic analyses should also be made of the samples under study to help in the rational development of a wider range of preventive measures and better control of hospital-contracted infections. (c) 2005 Published by Elsevier SAS.