8 resultados para Mones, Husain

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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The paper deals with the petrographic and geochemical investigation of basalt flows present in a gravel quarry in the town of Monções in northwestern São Paulo State, members of the Serra Geral Formation of the Paraná Basin. Were collected 11 samples from different horizons within a topographic vertical profile with an average of 18 meters in height. The samples were subjected to macroscopic and microscopic petrographic and chemical major, minor and trace. The results indicated that it is tholeiitic basalts with dense fine grained average. Petrographic analyzes show that basalts studied are basically constituted by plagioclase (between 33 and 49%), labradorite and clinopyroxenes (between 29 and 46%) represented by the subordinate pigeonite and augite, having as accessories opaque (between 3 and 15% ), olivine (<2%), apatite and zircon as dashes. The secondary minerals correspond to cloropheite, chlorite, serpentine, epidote, albite and iron oxides and hydroxy as well as bowlingit of clay, nontronite, and celadonite. The basalts are kind of high-titanium (Hti)> 1.8% TiO2, and apparently belong to the Pitanga magma-type. The geochemical analyzes proved unsatisfactory for the determination of a probable lithogeochemistry differentiation within the vertical stroke for generating multiple data correlation or no immediately discernible trends

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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In the post Cold War period, in the security field, has increased the mechanisms of cooperation and coordination among the Latin American states, in the context of so called confidence-building measures. These arrangements presented as important and efficient tools of political-strategic articulation and assist in the maintenance of peace in the region. The paper presents some considerations about the current scenario in terms of security and defense in Latin America. Initially, presents concepts of security and defense and perceptions of threats by the states. Then, discusses the mechanisms of cooperation and coordination in security have been established on the American continent in the periods of the Cold War and post Cold War. Finally, presents considerations regarding the scenario and the prospects of security issues in the region.

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Desde perspectivas poscoloniales, se pretende comprender el tema de la mirada latinoamericana sobre las Relaciones Internacionales, teniendo como ejes las formaciones de identidades de la "periferia" del sistema internacional, las cuales poseen reminiscencias de los procesos coloniales. Por lo tanto, iniciamos con las siguientes preguntas: "¿Cuál es el papel de la cultura en la política mundial?", "Es posible entender las Relaciones Internacionales como un campo de conocimiento sin tener en cuenta las voces silenciadas por los procesos históricos de colonización?", "¿Cuáles son las características del sistema internacional actual y cuál es la relación entre ellas y los procesos locales de subordinación en América Latina? ". En base a estas preguntas, tratamos de contextualizar la disciplina de RI como poseedora de dinámicas de poder internas, que son influenciadas por la coyuntura jerárquica y colonial del sistema internacional, configurando, así, un círculo de prácticas y fundamentos teóricos que afectan localidades fuera de los grandes centros de poder.

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Bacterial quorum sensing (QS) is a density dependent communication system that regulates the expression of certain genes including production of virulence factors in many pathogens. Bioactive plant extract/compounds inhibiting QS regulated gene expression may be a potential candidate as antipathogenic drug. In this study anti-QS activity of peppermint (Menthe piperita) oil was first tested using the Chromobacterium violaceum CVO26 biosensor. Further, the findings of the present investigation revealed that peppermint oil (PMO) at sub-Minimum Inhibitory Concentrations (sub-MICs) strongly interfered with acyl homoserine lactone (AHL) regulated virulence factors and biofilm formation in Pseudomonas aeruginosa and Aeromonas hydrophila. The result of molecular docking analysis attributed the QS inhibitory activity exhibited by PMO to menthol. Assessment of ability of menthol to interfere with QS systems of various Gram-negative pathogens comprising diverse AHL molecules revealed that it reduced the AHL dependent production of violacein, virulence factors, and biofilm formation indicating broad-spectrum anti-QS activity. Using two Escherichia colt biosensors, MG4/pKDT17 and pEAL08-2, we also confirmed that menthol inhibited both the las and pqs QS systems. Further, findings of the in vivo studies with menthol on nematode model Caenorhabditis elegans showed significantly enhanced survival of the nematode. Our data identified menthol as a novel broad spectrum QS inhibitor.