23 resultados para Immigration and Refugee Board

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Esse artigo tem por objetivo apresentar e discutir aspectos de interesse sanitário no processo de imigração estrangeira para o estado de São Paulo, na primeira década após a proclamação da República. Objetiva também apresentar as relações da imigração com a formação dos serviços sanitários estaduais e com a elaboração do modelo tecno-assistencial por eles adotado a partir da década de 1890. Num momento em que a febre amarela era a mais freqüente e letal das epidemias que afetavam o estado, matando principalmente os estrangeiros, a defesa do fluxo migratório foi um dos fios condutores das ações em saúde pública. A combinação entre os interesses da cafeicultura, a expansão ferroviária, imigração e febre amarela definiu os rumos da ação sanitária promovida pelas oligarquias no poder nesse período em São Paulo. A organização autoritária do Estado brasileiro não dava espaço à implantação de ações individuais de assistência à saúde. Sempre reivindicada pela população urbana e rural, somente com o desenvolvimento da medicina previdenciária no país, na década de 1930, difundiram-se as ações de assistência individual à saúde.

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Crotoxin is the major component of Crotalus durissus terrificus venom. In view of the presence of high-affinity specific binding sites for crotoxin in the brain, the objective of this work was to investigate whether crotoxin induces behavioral effects in the open-field and hole-board tests. Adult male Wistar rats (180-220 g) treated with crotoxin, 100, 250 and 500 mu g/kg, ip, administered 2 h before the test, presented statistically significant behavioral alterations (ANOVA for one-way classification complemented with Dunnet test, P<0.05). In the open-field test, 250 and 500 mu g/kg of crotoxin increased freezing (from 3.22 sec to 10.75 sec and 11.2 sec) and grooming (from 13.44 sec to 22.75 sec and 21.22 sec) and decreased ambulation (from 64.8 to 39.38 and 45.8). The dose of 500 mu g/kg also decreased rearing (from 24.9 to 17.5). In the hole-board test, 500 mu g/kg of crotoxin decreased head-dip count (from 6.33 to 4.00). All the crotoxin-induced behavioral effects were antagonized by an anxiolytic dose of diazepam (1.5 mg/kg, ip, 30 min before the tests). These results show that crotoxin reduced open-field activity and exploratory behavior as well. We suggest that these effects express an increased emotional state induced by this toxin.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Present work investigated the effect of prolonged administration of salmon calcitonin, a hormone secreted by parafollicular cells from thyroid, on behavioural parameters of rats. Animals received calcitonin sc, 100 mUI/100 g of body weight, three times a week, during 50 days. Behaviour was assessed utilizing an Open Field, Elevated Plus-Maze and Hole Board apparatus. Calcitonin treatment in rats seems to modify open field and elevated plus maze behaviour, suggesting emotionality and anxiety state alterations of the animals. These conditions can be provoked due to the direct calcitonin action on its receptors, even though we do not exclude an action mediated by tissue calcium level alterations.

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The hybrid Mentha pulegium x spicata, also well-known as poejo de praia, it is a perennial, low plant, with fields, violet stem and opposite leaves, with lance format and sawed board, presenting characteristic smell. The objective of the present work was accomplish a study of the leaf anatomy, including a biometric study of tissue and quantitative analysis of secretory trichomes/mm2 and of stomata/mm2 in both faces of the epidermis, besides a chemical analysis of the essential oil. Histological permanent laminas were made for anatomical analysis of the leaf surface and also sheets of the impression to foliate for the count of the trichomes number and stomatas. The chemical studies were made through the extraction of the essential oil by hydrodistillation and analyzed in GC-MS. The capitate and peltates trichomes are present on both sides of the leaf, even so they prevail in the abaxial surface. The variance analysis show that there are significant differences for the number of capitate trichomes and tectores between the adaxial and abaxial surfaces, but they are not significant for the peltate trichoma. The analyzed of essential oil shows the presence of a majority component, trans piperitone epoxide, being it responsible for more than 80% of the relative composition in the essential oil.

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The structure of an ecological community is shaped by several temporally varying mechanisms. Such mechanisms depend in a large extent on species interactions, which are themselves manifestations of the community's own structure. Dynamics and structure are then mutually determined. The assembly models are mathematical or computational models which simulate the dynamics of ecological communities resulting from a historical balance among colonizations and local extinctions, by means of sequential species introductions and their interactions with resident species. They allow analyzing that double relationship between structure and dynamics, recognizing its temporal dependence. It is assumed two spatiotemporal scales: (i) a local scale, where species co-occur and have their dynamics explicitly simulated and (ii) a regional scale without dynamics, representing the external environment which the potential colonizers come from. The mathematical and computational models used to simulate the local dynamics are quite variable, being distinguished according to the complexity mode of population representation, including or not intra or interspecific differences. They determine the community state, in terms of abundances, interactions, and extinctions between two successive colonization attempts. The schedules of species introductions also follow diverse (although arbitrary) rules, which vary qualitatively with respect to species appearance mode, whether by speciation or by immigration, and quantitatively with respect to their rates of introduction into the community. Combining these criteria arises a great range of approaches for assembly models, each with its own limitations and questions, but contributing in a complementary way to elucidate the mechanisms structuring natural communities. To present such approaches, still incipient as research fields in Brazil, to describe some methods of analysis and to discuss the implications of their assumptions for the understanding of ecological patterns are the objectives of the present review.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em História - FCHS

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Geografia - IGCE

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)