Reproductive migration of fish and movement in a series of reservoirs in the Upper Parana River basin, Brazil

AbstractThis study evaluates the effectiveness of two fish passes at two hydropower dams (Canoas I and II) in the Upper Parana basin, which form part of a cascade of three reservoirs. Fish from 12 migratory species (3089 specimens) were captured during their ascending, reproductive migration and were tagged with hydrostatic tags. The recapture data (294 specimens over two consecutive years) showed that there is a strong tendency for the maintenance of ascending migration through reservoirs with fish passes but with differences in migratory activity within the same species. No eggs, larvae or juveniles of these species were found in samples collected over 5 years in the reservoirs above the fish passes. These data suggest that fish passes have contributed to the restoration of the migratory routes of adult fish but that in the absence of suitable spawning or nursery habitats for these species; they probably act as ecological traps and do not contribute to the recruitment of the species.

Neutrophil migration induced by IL-1β depends upon LTB4 released by macrophages and upon TNF-α and IL-1β released by mast cells

In the present study, we investigate whether mast cells and macrophages are involved in the control of IL-1β-induced neutrophil migration, as well as the participation of chemotactic mediators. IL-1β induced a dose-dependent neutrophil migration to the peritoneal cavity of rats which depends on LTB 4, PAF and cytokines, since the animal treatment with inhibitors of these mediators (MK 886, PCA 4248 and dexamethasone respectively) inhibited IL-1β-induced neutrophil migration. The neutrophil migration induced by IL-1β is dependent on mast cells and macrophages, since depletion of mast cells reduced the process whereas the increase of macrophage population enhanced the migration. Moreover, mast cells or macrophages stimulated with IL-1β released a neutrophil chemotactic factor, which mimicked the neutrophil migration induced by IL-1β. The chemotactic activity of the supernatant of IL-1β-stimulated macrophages is due to the presence of LTB4, since MK 886 inhibited its release. Moreover, the chemotactic activity of IL-1β-stimulated mast cells supernatant is due to the presence of IL-1β and TNF-α, since antibodies against these cytokines inhibited its activity. Furthermore, significant amounts of these cytokines were detected in the supernatant. In conclusion, our results suggest that neutrophil migration induced by IL-1β depends upon LTB4 released by macrophages and upon IL-1β and TNFα released by mast cells. © 2007 Springer Science+Business Media, LLC.

The importance of sensing one's movement in the world for the sense of personal identity

Within philosophy and cognitive science, the focus in relation to the problem of personal identity has been almost exclusively on the brain. We submit that the resulting neglect of the body and of bodily movements in the world has been detrimental in understanding how organisms develop a sense of identity. We examine the importance of sensing one’s own movements for the development of a basic, nonconceptual sense of self. More specifically, we argue that the origin of the sense of self stems from the sensitivity to spontaneous movements. Based on this, the organism develops a sense of “I move” and, finally, a sense of “I can move”. Proprioception and kinesthesis are essential in this development. At the same time, we argue against the traditional dichotomy between so-called external and internal senses, agreeing with Gibson that perception of the self and of the environment invariably go together. We discuss a traditional distinction between two aspects of bodily self: the body sense and the body image. We suggest that they capture different aspects of the sense of self. We argue that especially the body sense is of great importance to our nonconceptual sense of self. Finally, we attempt to draw some consequences for research in cognitive science, specifically in the area of robotics, by examining a case of missing proprioception. We make a plea for robots to be equipped not just with external perceptual and motor abilities but also with a sense of proprioception. This, we submit, would constitute one further step towards understanding creatures acting in the world with a sense of themselves.

Evaluation of mesenchymal stem cell migration after equine tendonitis therapy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Heterorhabditis amazonensis RSC5 (Rhabditida: Heterorhabditidae) movement and host recognition

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Identificação de áreas sujeitas a processos erosivos na área urbana do município de Aparecida, SP

Historically, in Brazil, the process of urbanization and city growth was due to the intense migration of rural population to urban areas, especially in the last thirty years. This move, combined with a lack of planning, allowed the occupation of areas with potential for occurrences of erosion. The city of Aparecida, SP can be cited as an example of this process. These irregular occupations generate large material damage and human losses conditioned on mass movement of soil, resulting from the development of erosive processes. So, it is of great importance to physical characterization and identification of these areas within the same city map as a way to minimize the effects and mitigate the consequences of events. Thus, this work presents a series of graduate field campaigns, geotechnical laboratory testing and consultation with representative maps of the physical environment, as a means conclusive for delimintation of areas with potential risk for the occurrence of erosion, especially in areas undergoing urban expansion of the city Aparecida, SP. These areas were determined some geotechnical properties of soils present, evaluating the potential erodibility of them. Also presented are the descriptions of the main characteristics of these areas identified as being at risk, along with proposals to avoid or minimize the impact of problems related to erosion processes on the local population

Território migratório - contigüidade socioterritorial de terras distintas: os Dekasseguis e a busca pela reterritorialização

This paper analyzes the new trends of Brazilian migration to Japan, more specifically in the process of redefining its territoriality on the political and administrative Japanese territory. This migration, known as Dekassegui movement, is based on the flow of Brazilians of Japanese descent in this country. The working part of a periodization of the movement, considering the political and economic situations of countries and account for aspects of the difficult adjustment of the pioneers, the change the temporal expectation of return and search for repossession of these immigrants in their most recent time frame After more than 27 years of migration is still common difficulties in the integrating the Brazilian front of Japanese society, and it is in this context, however, that migration projects take new directions, new meanings are created networks, strengthens relationships, change and so plans to build a new interaction with the territory. To understand this process, we consider as a theoretical analysis and territorial consolidation of field research in Japan, through questionnaires, to identify the processes of social integration of immigrants

Effects of lithium on the proliferation and migration of neuroblasts in the rostral migratory stream in adult mice

The discovery of neurogenesis in adult brains opened the possibility of cellular therapy strategies for the treatment of neurodegenerative diseases, such as Alzheimer’s disease. Neurogenesis in the adult brain occurs in two areas: subgranular zone of the hippocampus and subventricular zone (SVZ) of the lateral ventricles. Neurons that originate from the SVZ migrate to the olfactory bulb (OB) through the rostral migratory stream (RMS). In Alzheimer’s disease, there is a progressive neuronal dysfunction and degeneration, resulting in brain atrophy and cognitive impairments including olfactory dysfunction. Several studies have demonstrated that pharmacological treatment with lithium exerts positive effects on adult neurogenesis, and one pathway seems to be the modulation of factors that regulate the migration of neuroblasts. The objective of this study was to investigate whether treatment with lithium promotes the increase of migratory neuroblasts using as parameter the RMS. Adult male C57BL/6 mice were divided into control and lithium-treated groups. The animals were treated for 6 weeks and, at four different time points, i.e., 10 days, 7 days, 3 days and 1 day before the end of treatments, they received an injection of BrdU (cell proliferation marker). The animals were sacrificed by perfusion fixation and the brains were immunohistochemically labeled for BrdU for analysis of migrating neuroblasts in the RMS. The results showed that the number of BrdU+ cells in the RMS was not significantly different between the two groups, suggesting that lithium, alone, is not capable of increasing the number of neuroblasts migrating from the SVZ to the OB

Migração e trabalho: impactos do processo migratório na vivência da mulher nordestina

Pós-graduação em Serviço Social - FCHS

Cuspal movement related to different polymerization protocols

Objective: The aim of this study to investigate the effects of different polymerization protocols on the cuspal movement in class II composite restorations. Materials and methods: Human premolar teeth were prepared with class II cavities and then restored with composite and three-step and two-step etch-and-rinse adhesive systems under different curing techniques (n = 10). It was used a lightemittingdiode curing unit and the mode of polymerization were: standard (exposure for 40 seconds at 700 mW/cm2), pulse-delay (initial exposure for 6 seconds at 350 mW/cm2 followed by a resting period of 3 minutes and a final exposure of 37 seconds at 700 mW/cm2) and soft-start curing (exposure 10 seconds at 350 mW/cm2 and 35 seconds at 700 mW/cm2). The cuspal distance (µm) was measured before and after the restorative procedure and the difference was recorded as cuspal movement. The data were submitted to two-way ANOVA and Bonferroni test (p < 0.05). Results: The type of adhesive system did not influenced the cuspal movement for all the curing methods. Standard protocol showed the highest values of cuspal movement and was statistically different from the pulse-delay and soft-start curing modes. Conclusion: Although the cuspal displacement was not completely avoided, alternative methods of photocuring should be considered to minimize the clinical consequences of composites contraction stress.

Monocyte migration driven by galectin-3 occurs through distinct mechanisms involving selective interactions with the extracellular matrix

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of alendronate sodium on tooth movement in ovariectomized rats

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Nitric oxide and brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis

The fact that drugs currently used in the treatment of Leishmania are highly toxic and associated with acquired resistance has promoted the search for new therapies for treating American tegumentary leishmaniasis (ATL). In this study, BALB/c mice were injected in the hind paw with Leishmania (Leishmania) amazonensis and subsequently treated with a combination of nitric oxide (NO) donor (cis-[Ru(bpy)(2)imN(NO)](PF6)(3)) (Ru-NO), given by intraperitoneal injection, and oral Brazilian propolis for 30 days. Ru-NO reached the center of the lesion and increased the NO level in the injured hind paw without lesion exacerbation. Histological and immunological parameters of chronic inflammation showed that this combined treatment increased the efficacy of macrophages, determined by the decrease in the number of parasitized cells, leading to reduced expression of proinflammatory and tissue damage markers. In addition, these drugs in combination fostered wound healing, enhanced the number of fibroblasts, pro-healing cytokines and induced collagen synthesis at the lesion site. Overall, our findings suggest that the combination of the NO donor Ru-NO and Brazilian propolis alleviates experimental ATL lesions, highlighting a new therapeutic option that can be considered for further in vivo investigations as a candidate for the treatment of cutaneous leishmaniasis.

Impairment of neutrophil migration to remote inflammatory site during lung histoplasmosis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)