Heterologous expression and biochemical and functional characterization of a recombinant alpha-type myotoxin inhibitor from Bothrops alternatus snake

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Impedance-derived electrochemical capacitance spectroscopy for the evaluation of lectin-glycoprotein binding affinity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pruning methods to MLP neural networks considering proportional apparent error rate for classification problems with unbalanced data

This article deals with classification problems involving unequal probabilities in each class and discusses metrics to systems that use multilayer perceptrons neural networks (MLP) for the task of classifying new patterns. In addition we propose three new pruning methods that were compared to other seven existing methods in the literature for MLP networks. All pruning algorithms presented in this paper have been modified by the authors to do pruning of neurons, in order to produce fully connected MLP networks but being small in its intermediary layer. Experiments were carried out involving the E. coli unbalanced classification problem and ten pruning methods. The proposed methods had obtained good results, actually, better results than another pruning methods previously defined at the MLP neural network area. (C) 2014 Elsevier Ltd. All rights reserved.

Tissue inhibitor of matrix metalloproteinase-1 polymorphism, plasma TIMP-1 levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Conversion between basic density and apparent density at any moisture content in Eucalyptus grandis

Wood basic density (BD) is related to other wood characteristics and its determination is important in forest inventory, though BD must be differentiated from the apparent density (AD), which relates to the moisture content (MC) of wood. The aim of this study is to demonstrate a reliable conversion from BD to AD for any MC of Eucalyptus grandis wood based on two exponential and linear models that relate volumetric shrinkage to MC. To this end, wood specimens were submitted to drying and the volumetric shrinkage was determined as a function of MC. The two models proved to be efficient in the conversion of BD to AD and vice versa.

CrataBL, a lectin and Factor Xa inhibitor, plays a role in blood coagulation and impairs thrombus formation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Electrocatalytic effect of Pb and Sn adatoms on the oxidation of 1-propanol on platinized platinum electrodes: Determination of the apparent activation energy

The electrocatalytic oxidation of 1-propanol was investigated on platinum electrodes modified by submonolayers of Pb and Sn in acid media. An increase of oxidation rates observed for both Pb and Sn, and the influence of theta values was investigated. The values of the apparent activation energy evaluated from the Arrhenius plots concerning the electrochemical oxidation of 1-propanol on modified platinzed platinum electrodes, reveal a significant decrease in the presence of upd Sn and Ph adatoms. A decrease from 56 to 26 U mol(-1) in the presence of Sn. and from 78 to 25 U mol(-1) for Ph adatoms are some illustrative values which reflect the promoting effect of the upd adatoms.

O passado no presente: João Gilberto Noll, leitor de Álvares de Azevedo

In the mid-nineteenth century, in his fruitful years of the perhaps best-known shortest literary career, Álvares de Azevedo wrote this verse “As ondas são anjos que dormem no mar” (“The waves are angels who sleep in the sea”). In the presentation of João Gilberto Noll’s young adult novel Anjo das ondas (Angel of the waves) in 2010, Ivan Marques states that the character in the novel, Gustavo, “with his adolescent passion, and torn spirit with overflowing lyrics, could even be compared to our tropical Byron”. João Gilberto Noll establishes a connection between him and Álvares de Azevedo that invites the reader to go beyond a first reading level of his work, seeking evidence of dialogue ratification between two apparently distant writers. The subtle intertextuality exceeds the initial clue and can be detected on Noll’s theme development from the history of Gustavo, a troubled teenager in search of his identity. Noll’s affinity to Álvares de Azevedo can still be captured in his narrative texture, in voices coming from his text; however, they also reveal to be unique and original features of his literary production. An apparent exercise in style shows that each author fulfills his mission by expressing, in his own way, the feeling of his time. In addition, it shows that through aesthetic emotion, literature allows us to transcend time and space.

Investigação do envolvimento de subtipos de adrenoceptores α1 no efeito anti-imobilidade da imipramina no teste de suspensão pela cauda

Pós-graduação em Ciências Biológicas (Farmacologia) - IBB

Correlation Between Apparent Activation Energy and NOx emission of renewable diesel from sugar cane, biodiesel, fossil diesel and their blends

Biofuels and their blends with fossil fuel are important energy resources, which production and application have been largely increased internationally. This study focus on the development of a correlation between apparent activation energy (Ea) and NOx emission of the thermal decomposition of three pure fuels: farnasane (renewable diesel from sugar cane), biodiesel and fossil diesel and their blends. Apparent Activation energy was determined by using thermogravimetry and Model-Free Kinetics. NOx emission was obtained from the European Stationary Cycle (ESC) with OM 926LA CONAMA P7/Euro 5 engine. Results showed that there is a linear correlation between apparent activation energy and NOx emission with R2 of 0,9667 considering pure fuels and their blends which is given as: NOx = 2,2514Ea - 96,309. The average absolute error of this correlation is 2.96% with respect to the measured NOx value. The main advantage of this correlation is its capability to predict NOx emission when either a new pure fuel or a blend of fuels is proposed to use in enginees.

Effectiveness inactivation of trypsin inhibitor fron brazilian cultivarof beans (Phaseolus vulgaris L.)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Apparent protein and energy digestibility and amino acid availability of corn and co-products in extruded diets for nile tilapia, oreochromis niloticus

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)