Volumetric microleakage assessment of glass-ionomer-resin composite hybrid materials

Objective: This study was intended to quantify the marginal leakage of three glass-ionomer-resin composite hybrid materials and compare it with the leakage exhibited by a glass-ionomer cement and a bonded resin composite system. Method and materials: Standardized Class V cavities were prepared on root surfaces of 105 extracted human teeth, randomly assigned to five groups of 21 each, and restored with either Ketac-Fil Aplicap, Z100/Scotchbond Multi-Purpose Plus, Vitremer, Photac-Fil Aplicap, or Dyract. The teeth were thermally stressed for 500 cycles and stained with methylene blue. The microleakage was quantified spectrophotometrically, and the data were statistically analyzed with Friedman's test. Results: There were no significant differences in microleakage among the five groups. Restorations of all tested materials showed some marginal leakage in Class V cavities. Conclusion: The microleakage performance of glass-ionomer-resin composite hybrid materials was similar to those of a conventional glass-ionomer and a bonded resin composite system.

Desempenho motor de escolares com dislexia, transtornos e dificuldades de aprendizagem

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise eletromiográfica dos músculos vasto medial e vasto lateral durante contrações isométricas de extensão do joelho

O joelho, por suas características anatômicas e freqüente instabilidade e exposição as lesões tem o quadríceps como importante músculo a ser desenvolvido quanto ao seu trofismo e força. Composto de quatro porções distintas estas podem gerar diferentes vetores de força que podem ter relações diretas com o recrutamento de unidades motoras. O posicionamento articular, a conseqüente modificação do comprimento muscular e a intensidade da contração podem influenciar o desenvolvimento da força do quadríceps. Dentre as contrações relacionadas ao maior recrutamento de unidades motoras com o intuito do desenvolvimento de força está a contração isométrica. Dentre as contrações musculares, as isométricas têm sido frequentemente indicadas para aumentar a força e estabilidade articular em sessões de treinamento e reabilitação. Pelo exposto, o objetivo do estudo foi analisar os músculos vasto medial (VM) e vasto lateral (VL) por meio da eletromiografia de superfície durante 15s de contração isométrica a 20%, 30%, 40% e 50% da contração isométrica voluntária máxima – CIVM com o joelho a 90 graus. Foram utilizados eletrodos de superfície bipolar de Ag/AgCl, posicionados nos músculos VM e VL, um módulo de aquisição de sinais biológicos (Lynx) calibrado com ganho de 1000vezes, filtro de passa alta de 20Hz e de passa baixa de 500Hz. Uma célula de carga foi acoplada perpendicularmente à cadeira de teste especialmente desenvolvida para o estudo e utilizado uma indicador digital para retorno visual. Na análise estatística utilizou-se teste de Friedman e teste de Wilcoxon, e adotou-se nível de significância de p<0,05. Verificou-se que os músculos VM e VL foram semelhantes entre si, e entre as cargas, houve diferença significante entre as cargas de 20% e 40%, 20% e 50%, e 30% e 50% para ambos os músculos, com maior atividade nas cargas de 40% e 50% CVM... (Resumo completo, clicar acesso eletrônico abaixo)

Avaliação da motilidade e do trânsito gastrintestinal de equinos após injeção epidural de morfina ou tramadol

Pós-graduação em Cirurgia Veterinária - FCAV

Remodeling of cortical and corticocancellous fresh-frozen allogeneic block bone grafts - a radiographic and histomorphometric comparison to autologous bone grafts

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Can repair increase the longevity of composite resins? Results of a 10-year clinical trial

The aim of this double-blind clinical trial was to assess the longevity of repairs to localized clinical defects in composite resin restorations that were initially planned to be treated with a restoration replacement. Methods Twenty-eight patients aged 18–80 years old with 50 composite resin restorations (CR) were recruited. The restorations with localized, marginal, anatomical deficiencies and/or secondary caries adjacent to CR that were “clinically judged” to be suitable for repair or replacement according to the USPHS criteria were randomly assigned to Repair (n = 25) or Replacement (n = 25) groups, and the quality of the restorations was scored according to the modified USPHS criteria. The restorations were blind and two examiners scored them at baseline (Cohen Kappa agreement score 0.74) and at ten years (Cohen Kappa agreement score 0.87) restorations. Wilcoxon tests were performed for comparisons within the same group (95% CI), and Friedman tests were utilized for multiple comparisons between the different years within each group. Results Over the decade, the two groups behaved similarly on the parameters of marginal adaptation (MA) (p > 0.05), secondary caries (SC) (p > 0.05), anatomy (A) (p < 0.05), and colour (C) (p > 0.05). Conclusions Given that the MA, SC, A and C parameters behaved similarly in both groups, the repair of composite resins should be elected when clinically indicated, because it is a minimally invasive treatment that can consistently increase the longevity of restorations. Clinical significance The repair of defective composite resins as an alternative treatment to increase their longevity proved to be a safe and effective treatment in the long term.

Preventive effect of a high fluoride toothpaste and arginine-carbonate toothpaste on dentinal tubules exposure followed by acid challenge: a dentine permeability evaluation

Coordenação de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

Osteopatia como meio terapêutico nas disfunções temporomandibulares e dores orofaciais

Pós-graduação em Biopatologia Bucal - ICT

Charge effect in the interaction of doxorubicin and derivatives with polydeoxynucleotides

The equilibrium interaction of doxorubicin and its N-acetyl derivative with a series of purine-pyrimidine alternating polydeoxynucleotides has been studied through spectrofluorometry to assess the relevance of the electrostatic contribution to DNA intercalation. The results have shown that: (a) the suppression of the positive charge on the aminosugar has: (I) a profound negative effect on the free energy of intercalation, as expected, and (II) a negligible influence on the base specificity, which supports the notion of an essentially electrostatic effect of N-acetylation on intercalation; (b) a reasonably good accord with the demands of a polyelectrolytic model, due to Friedman and Manning, is found.

Acute auditory stimulation with different styles of music influences cardiac autonomic regulation in men

No clear evidence is available in the literature regarding the acute effect of different styles of music on cardiac autonomic control. The present study aimed to evaluate the acute effects of classical baroque and heavy metal musical auditory stimulation on Heart Rate Variability (HRV) in healthy men. In this study, HRV was analyzed regarding time (SDNN, RMSSD, NN50, and pNN50) and frequency domain (LF, HF, and LF / HF) in 12 healthy men. HRV was recorded at seated rest for 10 minutes. Subsequently, the participants were exposed to classical baroque or heavy metal music for five minutes through an earphone at seated rest. After exposure to the first song, they remained at rest for five minutes and they were again exposed to classical baroque or heavy metal music. The music sequence was random for each individual. Standard statistical methods were used for calculation of means and standard deviations. Besides, ANOVA and Friedman test were used for parametric and non-parametric distributions, respectively. While listening to heavy metal music, SDNN was reduced compared to the baseline (P = 0.023). In addition, the LF index (ms(2) and nu) was reduced during exposure to both heavy metal and classical baroque musical auditory stimulation compared to the control condition (P = 0.010 and P = 0.048, respectively). However, the HF index (ms(2)) was reduced only during auditory stimulation with music heavy metal (P = 0.01). The LF/HF ratio on the other hand decreased during auditory stimulation with classical baroque music (P = 0.019). Acute auditory stimulation with the selected heavy metal musical auditory stimulation decreased the sympathetic and parasympathetic modulation on the heart, while exposure to a selected classical baroque music reduced sympathetic regulation on the heart.

Acute mucociliary clearance response to aerobic exercise in smokers

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Seal, replacement or monitoring amalgam restorations with occlusal marginal defects? Results of a 10-year clinical trial

The aim of this prospective and blind clinical trial was to assess the effectiveness of sealing localized marginal defects of amalgam restoration that were initially scheduled to be replaced. A cohort of twenty six patients with 60 amalgam restorations (n=44Class I and n=16Class II), that presented marginal defects deviating from ideal (Bravo) according to USPHS criteria, were assigned to either sealing or replacement groups: A: sealing n=20, Replacement n=20, and no treatment (n=20). Two blind examiners evaluated the restorations at baseline (K=0.74) and after ten years (K=0.84) according with USPHS criteria, in four parameters: marginal adaptation (MA), secondary caries (SC), marginal staining (MS) and teeth sensitivity (TS). Multiple comparison of restorations degradation/upgrade was analyzed by Friedman test and the comparisons within groups were performed by Wilcoxon test. After 10 years, 44 restorations were assessed (73.3%), Group A: n=14 and Group B: n=16; and Group C: n=14 sealing and replacement amalgam restorations presented similar level of quality in MA (p=0.76), SC (p=0.25) and TS (p=0.52), while in MS (p=0.007) presented better performance in replacement group after 10-years. Most of the occlusal amalgam restorations with marginal gaps showed similar long term outcomes than the restorations were sealed, replaced, or not treated over a 10-year period. Most of the restorations of the three groups were clinically acceptable, under the studied parameters. All restorations had the tendency to present downgrade/deterioration over time.

A geometric approach to cosmological boundary conditions

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Perfil de atividade e uso do recinto de Pinguim-de-Magalhães (Spheniscus magellanicus) em cativeiro

Os Pinguins-de-Magalhães (Spheniscus magellanicus) (Forster, 1781) são aves marinhas que se reproduzem em grandes colônias nas costas da Argentina, do Chile e nas Ilhas Malvinas. Quando animais desta espécie são mantidos em cativeiro, é frequente que deixem de exibir comportamentos típicos da espécie, tornando-se sedentários e apresentando baixo índice de reprodução. Nestas condições, por passarem muito tempo fora da água sustentando todo o peso do corpo sobre as patas apoiadas em piso firme, os pinguins podem desenvolver lesões nas patas denominadas pododermatites. Tendo em vista que o padrão temporal do comportamento é alterado por estressores e que o acompanhamento deste padrão pode contribuir para a determinação do bem estar animal, avaliamos neste estudo o padrão de atividade e de uso do recinto de três fêmeas e três machos residentes no Sabina Escola Parque do Conhecimento (Santo André, SP). Os animais foram observados por 2 a 3 dias em quatro períodos: janeiro, março, maio e julho de 2014. Foram realizadas seis varreduras sucessivas a cada 7 minutos nos seguintes intervalos de horários: 8h-8h50, 9h25-10h15, 10h50-11h40, 12h20-13h10, 13h40- 14h30 e 15h05-15h55. Em cada varredura foi registrado o estado comportamental (repouso, atividade ou não visível) e a área do recinto em que cada animal se encontrava (em quadrantes). Verificamos que os animais eram ativos na maior parte das observações visíveis: 73,4% das varreduras obtidas em janeiro, 65,8% em março, 89,0% em maio e 86,3% em julho. O coeficiente de atividade foi diferente entre os intervalos de horário: teste de Friedman em janeiro (Fr(3)=20,5; p=0,001), março (Fr(3)=19,9; p=0,001), maio (Fr(3)=15,4; p=0,01) e julho (Fr(3)=17,1; p=0,005); sendo que nos primeiros intervalos da manhã os animais eram mais ativos do que à tarde (post-hoc p<0,01). O uso da região frontal do recinto era maior pela manhã, momento sem visitação pública, nos meses de...

Yolks color definition by supplementing yellow and red xanthophylls to hen's diets

Egg yolk color may be controlled both by the concentration and the type of xanthophylls added to diets, with the aim of meeting consumers demand. The objectives of this work were to study how yellow and red xanthophylls present in laying hens` diets influence yolks colors and find the concentrations of these ingredients that meet the regional consumer desire. A factorial design 5 x 3 with 5 concentrations of yellow xanthophylls (lutein + zeaxantin 40%; 1.0, 1.25, 1.5, 1.75 and 2.0 mg/hen/d) and 3 concentrations of red xanthophylls (canthaxantin 10%; 0, 0.35, 0.7 mg/hen/d) was used. After a 30 d period receiving corn basal diets and water ad libitum, 60 White Dekalbe hens were distributed to receive the 15 dietary treatments in 4 replicates. Diets were provided daily at 110 g, during 21 d under 16 h light/8 h dark. Yolks colors were evaluated daily using the CIE L, a, b color space and the Roche color index. After the color stabilization, data were analyzed by ANOVA, regression analysis and Response Surface Methodology (MRS). Global acceptance for the Roche colors was evaluated with a 5 points hedonic scale and data were analyzed by Friedman and Dunn tests. Significance was established at 95% (P < 0.05). Regression analysis showed that the red xanthophylls content was the most important factor that defined L, a and b values for yolk color (P < 0.0001; square function), although its effect was significantly affected by the yellow xanthophylls contents (P = 0.0277; P < 0.0001; P = 0.0002 for L, a, b, respectively), providing evidence for a synergistic effect and not for a saturation effect. MRS showed that the highest redness of yolks was reached with 1.5 mg/hen/d of yellow and 0.5 mg/hen/d of red xanthophylls. So, higher supplementations aiming at increasing yolk color would bring an unnecessary cost to the ration. The most accepted yolk color scored 9, which corresponded to mean color attributes L = 65; a = 16; and b = 64. MRS showed that these values could be reached with combinations of yellow:red xanthophylls like 1.0:0.15 or 1.5:0.1 mg/ hen/d or simply with the yellow xanthophylls at 2.0 mg/hen/d. So, it was concluded that both yellow and red xanthophylls are important to define yolks color; that high amounts of xanthophylls are unnecessary to bring changes to color; and that Brazilian consumer requires yolks color attainable with few amounts of red xanthophylls or only with the yellow ones.