111 resultados para António Lopes
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A poesia de Adília Lopes merece nossa atenção crítica pela singularidade com que se recorta no atual panorama literário português. Em “Louvor do lixo”, por exemplo, poema contido em sua obra A mulher-a-dias (2002), é redimensionado o papel da poeta em um mundo marcado pela entropia e por formas desgastadas de sobrevivência. Operando com imagens alusivas ao cotidiano e dotando a linguagem poética de um funcionamento desestabilizador das convenções, Adília instiga no leitor questionamentos, não apenas sobre a subjetividade poética, como também sobre uma nova concepçãode lirismo, o qual inclui em seu fazer materiais imprevisíveis, desconcertantes. Nosso propósito é analisar como a autora promove tal desconcerto, por meio de procedimentos de construção presentes no poema mencionado. O gauchismo de Adília recupera um posicionamento transgressor que, embora já patente em poéticas de vanguarda do século XX, assume novas implicações ao gerar outros efeitos de sentido. A tradição cultural, o meio familiar, os valores poéticos, o erotismo são alguns dos aspectos que estão na mira da visão corrosiva da poeta, que não receia expor a si e à própria linguagem.
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Pós-graduação em Letras - FCLAS
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Alveolar bone resorption results from the inflammatory response to periodontal pathogens. Systemic diseases that affect the host response, such as type 1 diabetes mellitus (DM1), can potentiate the severity of periodontal disease (PD) and accelerate bone resorption. However, the biological mechanisms by which DM1 modulates PD are not fully understood. The aim of this study was to determine the influence of DM1 on alveolar bone resorption and to evaluate the role of receptor activator of nuclear factor-kappaB ligand (RANKL)/osteoprotegerin (OPG) in osteoclastogenesis in rats. PD was induced by means of ligature in nondiabetic and in streptozotocyn-induced DM1 rats. Morphological and morphometric analyses, stereology and osteoclast counting were performed. RANKL and OPG mRNA levels, protein content, and location were determined. PD caused alveolar bone resorption, increased the number of osteoclasts in the alveolar bone crest and also promoted changes in RANKL/OPG mRNA expression. DM1 alone showed alveolar bone destruction and an increased number of osteoclasts at the periapical and furcal regions. DM1 exacerbated these characteristics, with a greater impact on bone structure, resulting in a low OPG content and a higher RANKL/OPG ratio, which correlated with prominent osteoclastogenesis. This work demonstrates that the effects of PD and DM1 enhance bone destruction, confirms the importance of the RANKL signaling pathway in bone destruction in DM1 in animal models and suggests the existence of alternative mechanisms potentiating bone degradation in PD.
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Pós-graduação em Estudos Literários - FCLAR
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Este trabalho teve como propósito central analisar as relações entre o jornalismo e a literatura em Malhação do Judas Carioca (1975), de autoria João Antônio. A obra em análise mostrou ter sido estabelecida sob os auspícios da forma do conto-reportagem, com um regime de diálogo que ora se fixa na matriz jornalística, que ora se fixa no plano mais literário e ficcional. Para atingir tais objetivos, percorremos diversas etapas ao longo do desenvolvimento e elaboração do trabalho. Após delimitarmos conceitualmente as categorias de conto e reportagem e, assim, situarmos o lugar de João Antônio na imprensa e na literatura dos anos 1970, partiu-se, na segunda etapa da pesquisa, para a análise da obra Malhação. Este trabalho, fruto de pesquisa de iniciação científica para FAPESP, procurou se situar numa lacuna de estudos existente nos estudos de jornalismo autoral, dando especial ênfase à relação de João Antônio com o mundo jornalístico
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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This article has been generated by the interface between geography and music. Methodologically, we have used a multidisciplinary bibliography that contemplates cultural geography, history, music, linguistics, literature, anthropology, for we understand that, for the understanding of a polysemous code, as it is in music, we need a diversity of looks. Our main document for an analysis of the construction of Brasília is the “Sinfonia da Alvorada” (Symphony of the Dawn), composed by Antônio Carlos Jobim and Vinícius de Moraes. Here, we attempt mainly to do a textual analysis of the work under an external perspective of the symphonic work, we mean, analyzing more its semantics (considering the product between interlocution and interpretation), and less its instrumental aesthetics, although the latter is also present. Finally, we attempt to understand the connection that exists between the actors and the spaces which are metamorphosing along with the construction of the city and which puts into evidence the idea of social circularity, proposed by the “Sinfonia da Alvorada”. This piece captures social and cultural elements related to the construction of Brasília and repositions and rearranges it through the execution of the music, in such a way that this arrangement can provide a change in the senses which are constructed from the urban experience in Brasília.
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This paper deals with characteristically anti-authoritarian aspects of Antônio Carlos de Brito’s work, alias Cacaso (1944-1987). It aims to provide evidence on his peculiar poetry writing exercise, which incorporates political and aesthetic tensions into its own language, rather than just refer to them. By anchoring in a poetics of everyday life and by being engaged in a dialogue with Brazilian literary tradition, Cacaso manages image, tone and emotion in order to instantly illuminate the impasses of his generation.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Though benign, giant cell tumor of bone (GCTB) can become aggressive and can exhibit a high mitotic rate, necrosis and rarely vascular invasion and metastasis. GCTB has unique histologic characteristics, a high rate of multinucleated cells, a variable and unpredictable growth potential and uncertain biological behavior. In this study, we sought to identify genes differentially expressed in GCTB, thus building a molecular profile of this tumor. We performed quantitative real-time polymerase chain reaction (qPCR), immunohistochemistry and analyses of methylation to identify genes that are putatively associated with GCTB. The expression of the ADAM23 and CDKN2A genes was decreased in GCTB samples compared to normal bone tissue, measured by qPCR. Additionally, a high hypermethylation frequency of the promoter regions of ADAM23 and CDKN2A in GCTB was observed. The expression of the MAP2K3, MMP14, TIMP2 and VIM genes was significantly higher in GCTB than in normal bone tissue, a fact that was confirmed by qPCR and immunohistochemistry. The set of genes identified here furthers our understanding of the molecular basis of GCTB.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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This experiment aimed to determine the influence of supplementation with protected fat on nematode infections in periparturient sheep or sheep in their final stage of pregnancy. Fifty Santa Ines ewes received 200 g of concentrate/animal/day, mineral salt and water and were grouped according to their weight, hematocrit and the number of eggs per gram of feces (EPG). Two diets were used: a control treatment and a treatment consisting of supplementation with 30 g/animal/day of protected fat in the concentrate. Three monthly evaluations were performed over a total of 84 days of testing. The variables analyzed were weight, body condition, EPG and coprocultures; blood tests were performed for the determination of packed cell volume, hemoglobin concentration and total plasma protein, and leukograms and eosinophil counts were performed. For weight and hemoglobin concentrations, interactions were observed between diet and collection date (P<0.05); body condition, total plasma protein, packed cell volume and total leukocytes did not differ statistically among treatments (P> 0. 05) but did differ by collection day (P <0.05). The EPG and eosinophil counts did not differ statistically by either diet or collection date (P>0.05). The genus Haemonchus was predominant, followed by the genera Cooperia, Trichostrongylus and Oesophagostomum. The protected fat did not decrease EPG and did not improve the blood parameters of infected sheep.
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Considering the importance of spatial issues in transport planning, the main objective of this study was to analyze the results obtained from different approaches of spatial regression models. In the case of spatial autocorrelation, spatial dependence patterns should be incorporated in the models, since that dependence may affect the predictive power of these models. The results obtained with the spatial regression models were also compared with the results of a multiple linear regression model that is typically used in trips generation estimations. The findings support the hypothesis that the inclusion of spatial effects in regression models is important, since the best results were obtained with alternative models (spatial regression models or the ones with spatial variables included). This was observed in a case study carried out in the city of Porto Alegre, in the state of Rio Grande do Sul, Brazil, in the stages of specification and calibration of the models, with two distinct datasets.