Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Adding Motility Stimulants to Improve Freezing of Buffalo Sperm Recovered from Epididymal Cauda

The cryopreservation of epididymal sperm is important to preserve genetic material from valuable buffalo bulls. This study evaluated the viability of post-thawed sperm samples recovered from the epididymal cauda adding motility inductors. For that, were used epididymides from eight Murrah buffaloes with 18 months of age. Semen samples were submitted to three different conditions: (CT - control) without adding medium, (SPERM) adding Sperm Talp medium, and (FERT) adding Fert Talp medium. Immediately after slaughter, both testicles from each animal were collected and transported at 4 degrees C at maximum six hours interval. In laboratory, the removed epididymides was flushed to obtain sperm and diluted in the freezing extender. Each buffalo sperm were divided and fractions were submitted to all conditions (CT, SPERM and FERT). Semen doses were frozen at -196 degrees C. CT, SPERM and FERT post-thawing results were 13.63 +/- 8.91, 38.77 +/- 8.91 and 42.83 +/- 8.91 for total motility, 7.30 +/- 8.74, 24.87 +/- 8.74 and 29.70 +/- 8.74 for progressive motility, 6.04 +/- 0.92, 6.74 +/- 0.92 and 6.93 +/- 0.92 for percentage of rapid cells (P < 0.05). In conclusion, diluted semen supplementation with Sperm or Fert talp increases the motility of cauda epididymal sperm of buffalo bulls.

Efeito das cargas de treinamento sobre parâmetros fisiológicos de futebolistas

The aim of this study was to investigate the effects of three weeks of training with intensity monitored on the aerobic capacity of professional soccer players. Fourteen players, members of a first division Brazilian Championship team in 2010, aged 22.78 +/- 3.06 years were evaluated pre and post three weeks of training. The anaerobic threshold intensity LAn was determined by bi-segmented method, for this four submaximal efforts of 800 meters with intensities 10, 12, 14 and 16 km/h were applied. Thirty three training sessions were quantified in zones according to heart rate related to the LAn (FCLAn): Z1 - 10% below, Z2 - 90-100% and Z3 - above the FCLAn. During training participants remained 31.17 +/- 14.86%, 42.96% and 25.87 +/- 14.90 +/- 16.67% in Z1, Z2, and Z3 respectively. There were no significant differences in the LAn (pre = 13,29 +/- 0,71 km.h(-1); post = 12,85 +/- 0,90 km.h(-1)), perceived exertion (pre = 11,53 +/- 1,45 u.a; post = 11,23 +/- 1,53 u.a) and FCLAn (pre = 166,64 +/- 10,69 bpm; post = 174,50 +/- 10,89 bpm) between conditions before and after training, indicating that three weeks of training are insufficient to generate positive changes in soccer players LAn.

Writing saturated holograms in LiNbO3 crystals through phase control and double diffraction

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Yeasts found on an ephemeral reproductive caste of the leaf-cutting ant Atta sexdens rubropilosa

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A study of the role of the FOXP2 and CNTNAP2 genes in persistent developmental stuttering

A number of speech disorders including stuttering have been shown to have important genetic contributions, as indicated by high heritability estimates from twin and other studies. We studied the potential contribution to stuttering from variants in the FOXP2 gene, which have previously been associated with developmental verbal dyspraxia, and from variants in the CNTNAP2 gene, which have been associated with specific language impairment (SLI). DNA sequence analysis of these two genes in a group of 602 unrelated cases, all with familial persistent developmental stuttering, revealed no excess of potentially deleterious coding sequence variants in the cases compared to a matched group of 487 well characterized neurologically normal controls. This was compared to the distribution of variants in the GNPTAB, GNPTG, and NAGPA genes which have previously been associated with persistent stuttering. Using an expanded subject data set, we again found that NAGPA showed significantly different mutation frequencies in North Americans of European descent (p = 0.0091) and a significant difference existed in the mutation frequency of GNPTAB in Brazilians (p = 0.00050). No significant differences in mutation frequency in the FOXP2 and CNTNAP2 genes were observed between cases and controls. To examine the pattern of expression of these five genes in the human brain, real time quantitative reverse transcription PCR was performed on RNA purified from 27 different human brain regions. The expression patterns of FOXP2 and CNTNAP2 were generally different from those of GNPTAB, GNPTG and NAPGA in terms of relatively lower expression in the cerebellum. This study provides an improved estimate of the contribution of mutations in GNPTAB, GNPTG and NAGPA to persistent stuttering, and suggests that variants in FOXP2 and CNTNAP2 are not involved in the genesis of familial persistent stuttering. This, together with the different brain expression patterns of GNPTAB, GNPTG, and NAGPA compared to that of FOXP2 and CNTNAP2, suggests that the genetic neuropathological origins of stuttering differ from those of verbal dyspraxia and SLI. Published by Elsevier Inc.

Spontaneous healing responses detected by cone-beam computed tomography of horizontal root fractures: a report of two cases

Horizontal root fractures (HRF) usually affect the anterior teeth as a result of trauma, and generally heal spontaneously, depending on the vitality of the pulp. Diagnosis based on clinical findings, sensitivity tests, and radiographic examination is important to determine the presence of a root fracture and to prevent a root fracture from passing unnoticed. Cone-beam computed tomography (CBCT) has been used successfully for diagnosis and prognosis imaging of root fractures and has proved to be superior to other radiographic methods. This study reports two cases of dental trauma caused by a collision and a sports accident. The patients suffered horizontal root fractures in the maxillary left central incisor and in the mandibular left central incisor. The diagnosis of root fracture was confirmed by cone-beam computed tomography (CBCT) images, which also demonstrated spontaneous healing of the fracture line. The repair occurred by interposition of connective tissue in the former case and by interposition of bone and connective tissue in the latter case. The final diagnoses of both cases were based on CBCT images, indicating the importance of a CBCT examination to reach a firm diagnosis and to follow the healing process of root fracture cases, avoiding unnecessary radical endodontic treatment.

Produção de leite, duração da lactação e intervalo de partos em búfalas mestiças Murrah

This study aimed to evaluate the potential for milk production (MP), lactation length (LL) and calving interval (CI), analyze the environmental component affecting these traits, and to estimate the heritability and repeatability for milk production in crossbreds of Murrah buffalo cows in the state of Alagoas, Brazil. Data was composed of 487 observations of MP from 136 lactations recorded between the years of 2000 and 2010. In the analysis of variance for PL, the fixed effects were season (1- October to March, 2 -April to September) and year of the beginning of lactation, calving order and the LL (covariate). For the analysis of LL only the fixed effect of year of the beginning of lactation was included, and finally for the CI analysis, year of the beginning of lactation and calving order. The estimates of covariance were obtained using unicharacteristic analysis by Bayesian inference method, applyingan animal model, through Gibbs sampling. The additive genetic, permanent environment and residual effects were included as random effects in the model. The averages (sd) of MP, LL and CI were 2,218.03 kg (408.18), 282.59 days (39.48) e 422.49 days (91.05), respectively. All the effects included in the models were important (P<0.01). The estimates of heritability and repeatability for PL were 0.29 and 0.69, respectively. The results suggest that there is a moderate genetic variability among individuals for PL, indicating the possibility to obtain gain using selection.

Estrutura populacional de Oeceoclades maculata Lindl. (Orchidaceae), em um mosaico vegetacional (FEENA) da Floresta Estadual Edmundo Navarro de Andrade, Rio Claro, São Paulo

O objetivo do presente estudo foi avaliar a estrutura de população de O. maculata, através de sua distribuição espacial e estrutura de habitat, comparando características físicas e biológicas em diferentes fisionomias de Pinus spp. e Eucalyptus spp.. Foram montadas 86 parcelas de 5m por 10m, distribuídas uniformemente entre 4 áreas pré-estabelecidas de fisionomias distintas. Os indivíduos levantados foram separados em duas classes etárias, jovens e adultos, e contabilizou-se a taxa de predação, número de pseudobulbos e número de folhas. Os parâmetros ambientais avaliados foram cobertura herbácea, densidade de dossel, luminosidade e umidade de serrapilheira. A espécie apresentou densidades bastante elevadas nas áreas de plantios de eucalipto (1224 e 1733 indivíduos por hectare) e baixas nos plantios de pinus (88 e 26 individuos por hectare) o que levou as análises a se concentrarem nas fisionomias compostas por eucaliptos. O padrão de distribuição da espécie foi o agregado em todos os ambientes. Indivíduos adultos apresentaram significativamente um número médio de pseudobulbos maior que indivíduos jovens (Mann-Whitney; U = 24248.500; p<0,001), porém a diferença no número de folhas não foi significativa. A taxa de predação foliar em O. maculata entre as áreas de eucaliptos apresentou variação significativa. A variação do total de folhas predadas foi confirmada pelo teste Qui-quadrado de Pearson (X²=115.487; gl=1; p<0.001). A comparação de médias, com base no teste de Kruskal-Wallis, para cobertura de dossel (H(3,N=102)=28,534 p<0,001) e cobertura herbácea H(3,N=94)=28,246, p<0,001, mostrou taxas menores nas áreas de eucalipto. A umidade da serrapilheira foi menor (36,5%) nos locais onde a espécie apresentou agrupamentos, quando comparada aos locais de ausência (47,5%). Oeceoclades maculata Lindl. possui grande capacidade para colonizar ambientes... (Resumo completo, clicar acesso eletrônico abaixo)

Quantificação imunofenotípica de células T reguladoras em cães acometidos por linfoma multicêntrico submetidos ao protocolo quimioterápico chop associado ou não a um firocoxib

Pós-graduação em Medicina Veterinária - FCAV

A dominação masculina de Pierre Bourdieu: críticas e reflexões a partir da psicologia analítica

This bibliographical article aimed to analyze the work Masculine domination of Pierre Bourdieu, considering the concepts of Analytical Psychology from C. G. Jung. Among other issues, this psychological theory is based on the analysis of the masculine and feminine principles in order to bring a different apparatus for discussion of the ideas brought by Bourdieu that involves masculine domination. The Analytical Psychology concepts understand this domination from the patriarchal view of society, according to Bourdieu in submission question that this culture imposes on women. However, there were counterpoints regarding the quality and validation of female reference that Bourdieu’s theory seems to disqualify. Among the permanencies and changes of the structures that reproduce the masculine order, both theories show agreement with updates regarding the patriarchal structure.

Cuba-Estados Unidos: Oportunidades para las relaciones entre los dos países y propuestas para la colaboración en áreas de interés mutuo

O artigo comenta o dossier sobre el Taller Académico Cuba-Estados Unidos (TACE)

Eradication of a Mature Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilm From Acrylic Surfaces

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Os projetos políticos de Brasil e Venezuela para a América do Sul do século XXI: a UNASUL e a ALBA em uma perspectiva comparada

Coordenação de Aperfeiçoamento de Pessoal de Ensino Superior (CAPES)