109 resultados para 429
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Objectives: To evaluate the efficacy and safety of enhanced recovery after surgery (ERAS) programs in elective open surgical repair (OSR) of abdominal aortic aneurysm (AAA).Background: Open surgical repair of AAA is associated with high morbidity and mortality, prolonged hospital stay and high costs. ERAS programs contribute to the optimization of treatment by reducing hospital stay and improving clinical outcomes.Methods: A review of PubMed, EMBASE and LILACS databases was conducted. As only one randomized controlled trial was found, a pooled analysis of proportions from case series was conducted, considering it a complementary overview of the topic. Inclusion criteria were case series with more than five cases reported, adult patients who underwent an elective OSR of AAA and use of an ERAS program. ERAS was compared to conventional perioperative care. The pooled proportion and the confidence interval (CI) are shown for each outcome. The overlap of the CI suggests similar effect of the interventions studied.Results: Thirteen case series studies with ERAS involving 1,250 patients were compared to six case series with conventional care with a total of 1,429 patients. The pooled, respective proportions for ERAS and conventional care were: mortality, 1.51% [95% CI: 0.0091, 0.0226] and 3.0% [95% CI 0.0183, 0.0445]; and incidence of complications, 3.82% [95% CI 0.0259, 0.0528] and 4.0% [95% CI 0.03, 0.05].Conclusion: This review shows that ERAS and conventional care therapies have similar mortality and complication rates in OSR of AAA.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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The objective of this study is to identify the adoption level of practices associated with more sustainable agriculture and environmentally friendly practices. Additionally, the motivations for and barriers to the adoption of these practices by farmers are investigated. Data were collected through closed questionnaires taken by a random sample of farmers in the Southwest, Sao Paulo, Brazil, during the second half of 2013. Overall, sustainable agricultural practices recommended in the literature and analysed in this study are being not fully adopted by farmers of the studied area. The results showed that financial motivation is associated with farmers adopting new, more sustainable technology, whereas the lack of information on and lack of technical support for these technologies are significant barriers. Other results, research implications, limitations and suggestions for future research are presented.
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The process of knowledge representation as well as its procedures or tools and its products are not neutral in terms of values; instead they imply moral values. In this context, bias in representation related to prejudice and discrimination, to gender issues, to dicotomic categorization in classification systems or in thesauri and to lack of cultural warrant may arise. Concerning the problem of bias in indexing languages, starting from the initial theoretical reflexions of Brey (1999), Berman (1993), Olson (1998; 2002), Lopez-Huertas Perez & Torres Ramirez (2005), Guimaraes (2006), Hjorland (2008) and Milani et al. (2009), the proposal is to present a preliminary categorization aiming at facilitating the identification of bias concerning feminine issues in indexing languages, to offer a contribution to the theoretical universe of the specific questions of knowledge organization and to present a theme to be discussed by educators and professionals in the areas of cataloging, classification and indexing. If in a society which intends to be politically correct, social attitudes towards stigmatized citizens should be modified, then, the universe of indexing languages, taken as tools of knowledge representation, is a fertile field to sow this reflexion.
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Objective: This study was intended to quantify the marginal leakage of three glass-ionomer-resin composite hybrid materials and compare it with the leakage exhibited by a glass-ionomer cement and a bonded resin composite system. Method and materials: Standardized Class V cavities were prepared on root surfaces of 105 extracted human teeth, randomly assigned to five groups of 21 each, and restored with either Ketac-Fil Aplicap, Z100/Scotchbond Multi-Purpose Plus, Vitremer, Photac-Fil Aplicap, or Dyract. The teeth were thermally stressed for 500 cycles and stained with methylene blue. The microleakage was quantified spectrophotometrically, and the data were statistically analyzed with Friedman's test. Results: There were no significant differences in microleakage among the five groups. Restorations of all tested materials showed some marginal leakage in Class V cavities. Conclusion: The microleakage performance of glass-ionomer-resin composite hybrid materials was similar to those of a conventional glass-ionomer and a bonded resin composite system.
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Two new species of tarsonemid mites, Daidalotarsonemus annonae sp. nov. and Fungitarsonemus setillus sp. nov. found on Annonaceae leaves collected in northeastern Brazil are described and illustrated. Females of D. annonae are similar to those of D. serissae, but differ by having setae c2 setiform, and seta 1a distant from apodeme 1. F. setillus is similar to F. pereregrinus, but females can be distinguished by having the prodorsal shield fused to tergite C, dorsal setae h and d short, and setae c1 longer than c2.
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Purpose: The antitumor activity of Kielmeyera coriacea (Clusiaceae), a medicinal plant used in the treatment of parasitic, as well as fungal and bacterial infections by the Brazilian Cerrado population, was investigated. Methods: A chloroform extract (CE) of K. coriacea was tested in the murine melanoma cell line (B16F10-Nex2) and a panel of human tumor cell lines. Tumor cell migration was determined by the wound-healing assay and the in vivo antitumor activity of CE was investigated in a melanoma cell metastatic model. 1H NMR and GC/MS were used to determine CE chemical composition. Results: We found that CE exhibited strong cytotoxic activity against murine melanoma cells and a panel of human tumor cell lines in vitro. CE also inhibited growth of B16F10- Nex2 cells at sub lethal concentrations, inducing cell cycle arrest at S phase, and inhibition of tumor cell migration. Most importantly, administration of CE significantly reduced the number of melanoma metastatic nodules in vivo. Chemical analysis of CE indicated the presence of the long chain fatty compounds, 1-eicosanol, 1-docosanol, and 2-nonadecanone as main constituents. Conclusion: These results indicate that K. coriacea is a promising medicinal plant in cancer therapy exhibiting antitumor activity both in vitro and in vivo against different tumor cell lines.
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The application of ultrasonic waves during the initial setting of the glass ionomer cements (GIC) has demonstrated increase of the cure speed, reduction of air bubbles and improves in some mechanical properties. The aim of this study was to evaluate the effect of the ultrasound on the microhardness and the superficial roughness in two GICs (FUJI IX GP (GC Corporation) and Ketac Molar EasyMix (3M ESPE)). Forty specimens were confectioned, twenty for evaluation of the superficial roughness and twenty for evaluation of the microhardness. Half of them received for thirty seconds the ultrasonic waves application. The readings of the roughness had been carried before and after the toothbrushing test. The twenty remaining specimens had been polished with abrasive sandpapers of decreasing granulations and submitted to the hardness test. The results, analyzed for the variance analysis (ANOVA) (p<0,05), had demonstrated increase of the hardness for all the groups with the application of ultrasonic waves, being bigger for the Ketac Molar EasyMix. The ultrasound application also caused significant reduction of the superficial roughness for the Ketac Molar EasyMix. After the toothbrushing test, this last property increased for all the materials. It could be concluded that the application of ultrasonic waves was effective in increasing the superficial hardness of the materials and that it improved the roughness of the Ketac Molar EasyMix before the toothbrushing test.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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The synthesis of calcium titanate, CaTiO3, was performed by mechanical activation and thermal treatment. Milling for up to 360 minutes in a planetary ball mill mechanically activated an equimolar mixture of CaCO 3 and TiO2 powders. A small amount of mechanically activated mixtures was pressed into briquettes and calcined at 850°C for two hours. The effect of mechanical activation on the solid-state reaction was studied using X-ray powder diffraction and differential thermal analysis. The change of morphology and size of powder particles due to milling, were determined by SEM, while BET analysis was used to determine the specific surface area of the powder. The sintering process was followed by a dilatometer during thermal treatment up to 1300°C. The main conclusion of the analysis of conducted investigations is that CaTiO3 ceramics can be obtained from an activated mixture at a much lower temperature than reported in the literature owing to acceleration of the chemical reaction and sintering.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Pós-graduação em Biopatologia Bucal - ICT