Contemporaneidade e educações: mídias digitais nas culturas juvenis

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A relação das novas mídias de comunicação e o esporte: rupturas e conflitos para a formação moral a partir da representação social do futebol

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Swimming Exercise Changes Hemodynamic Responses Evoked by Blockade of Excitatory Amino Receptors in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Morphological and biochemical alterations activated by antitumor clerodane diterpenes

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação da presença de tecnologias de informação e comunicação no ensino de histologia das universidades de odontologia do estado de São Paulo

In recent decades the rise of the tools of information and communication technology (ICT) has been notorious. Currently ICTs are an important educational tool and is associated with the development of teaching methods courses in basic and higher education. Given the influence that these tools are currently engaged in several sectors, this project aimed to assess the frequency and manifestations of ICT that have been employed in the teaching of histology in the Schools of Dentistry of São Paulo. The virtual page of 43 Higher Education Institutions (HEI) was analyzed to search for links to sites of histology. With this assessment only 4 virtual domains were found which was present a narrow range of virtual tools such as hypertext, graphics, quizzes and lessons in electronic formats. Later, by sending a questionnaire to 46 teachers of histology of the Universities of São Paulo, were analyzed for the presence or absence of a site of discipline, mode and frequency of use of ICTs in education, and the value that teacher attaches to these tools. From the responses obtained were concluded that teachers who have websites in general have no interactivite tools and many seem to ignore the real representation of interactivity in teaching and the possibilities of applications of ICTs. However most teachers recognize the importance of education mediated by virtual tools

Relações públicas e mídias sociais: o desafio de construir relacionamentos na era da hiperconexão

This proposed project is to analyze the strategies for building and maintaining relationships, as well as the possibilities of intervention of the public relations in the virtual world. For this purpose, we used the multicase study of beer brands - Devassa, Nova Schin, Heineken, Skol and Brahma - to verify their roles in the communication process in their social media channels. Analyses were based on communication theories covering concepts such as the Excellence in Public Relations, the questioning about the definition of public flashing and discussion about the processes of interaction mediated by the Internet. The evaluation of the channels covered the period of 30 days and that the end of the checks it was found that most brands promote specific actions with surface interconnections between media channels, referring only to the effectiveness of social networks like Twitter, Facebook and Orkut in order to consolidate of relationships

Relações Públicas pela sustentabilidade: o profissional dentro das organizações

This research has the purpose of highlighting one of the acting areas of the public relations' professional, ensuring that he has enough competence to develop his work within an organization, implementing actions and programs in pursuit of a sustainable growth. The study starts with an analysis of the organizations and their communication process to further expand the understanding of the concept of sustainable development and finally addressing the role of public relations and the scenario organizational that it is envolved. In the globalized world we live in, our relationships are mediated by the capitalism: economic system that is concerned with the higher production seeking only profits. Thus, some organizations - acting in accordance with this model, end up don't caring about the environment around them, using it only like an instrument for achieving their goals. However, because this type of action, the contemporary society is facing serious environmental problems, fact that arouses the attention of civil society members and international organs, concerned to combine progress with sustainable development. The public relations' professional, concerned about the concretization of a concept and favorable institutional identities, besides the obvious envolvement with environment, can act in defense of this, implementing policies and campaigns ecologically correct for sustainability

Configurando um AVO (Ambiente Virtual Anise de Abreu Gonçalves D'Orange Ferreira de Orientação): instrumentação de um professor em proposta de incentivo ao uso de TIC e AVA no nível de pós-graduação

In this paper, I will present a proposal for teachers’instrumentation in ICT by the configuration of a virtual learningenvironment (MOODLE) for advising Linguistics graduate students’projects on teacher education and language teaching mediated by digitaltechnologies. The context of the proposal is teaching as work,occasioned by an announcement from the IHE to encourage the use ofICT. Following the theoretical assumptions adopted by the ALTERresearch group, and confronted with the goals set in the text of theannouncement, the instrumentation involved the reorganization ofcontents provided by a graduate course in the research process steps:planning, implementation and dissemination, and of the artifactsaffordances: information, communication and production.

Effect of hydrogen-peroxide-mediated oxidative stress on human dental pulp cells

To evaluate the effect of the oxidative stress on human dental pulp cells (HDPCs) promoted by toxic concentrations of hydrogen peroxide (H2O2) on its odontoblastic differentiation capability through time. Methods HDPCs were exposed to two different concentrations of H2O2 (0.1 and 0.3 μg/ml) for 30 min. Thereafter, cell viability (MTT assay) and oxidative stress generation (H2DCFDA fluorescence assay) were immediately evaluated. Data were compared with those for alkaline phosphatase (ALP) activity (thymolphthalein assay) and mineralized nodule deposition (alizarin red) by HDPCs cultured for 7 days in osteogenic medium. Results A significant reduction in cell viability and oxidative stress generation occurred in the H2O2-treated cells when compared with negative controls (no treatment), in a concentration-dependent fashion. Seven days after H2O2 treatment, the cells showed significant reduction in ALP activity compared with negative control and no mineralized nodule deposition. Conclusion Both concentrations of H2O2 were toxic to the cells, causing intense cellular oxidative stress, which interfered with the odontogenic differentiation capability of the HDPCs. Clinical significance The intense oxidative stress on HDPCs mediated by H2O2 at toxic concentrations promotes intense reduction on odontoblastic differentiation capability in a 7-day evaluation period, which may alter the initial pulp healing capability in the in vivo situation.

RANKL expression is differentially modulated by TLR2 and TLR4 signaling in fibroblasts and osteoblasts

Resident, non-immune cells express various pattern-recognition receptors and produce inflammatory cytokines in response to microbial antigens, during the innate immune response. Alveolar bone resorption is the hallmark of destructive periodontitis and it is caused by the host response to bacteria and their mediators present on the biofilm. The balance between the expression levels of receptor activator of nuclear factorkappa B ligand (RANKL) and osteoprotegerin (OPG) is pivotal for osteoclast differentiation and activity and has been implicated in the progression of bone loss in periodontitis. To assess the contribution of resident cells to the bone resorption mediated by innate immune signaling, we stimulated fibroblasts and osteoblastic cells with LPS from. Escherichia coli (TLR4 agonist), Porphyromonas gingivalis (TLR2 and -4 agonist), and interleukin-1 beta (as a control for cytokine signaling through Toll/IL-1receptor domain) in time-response experiments. Expression of RANKL and OPG mRNA was studied by RT-PCR, whereas the production of RANKL protein and the activation of p38 MAPK and NF-kB signaling pathways were analyzed by western blot. We used biochemical inhibitors to assess the relative contribution of p38 MAPK and NF-kB signaling to the expression of RANKL and OPG induced by TLR2, -4 and IL1β in these cells. Both p38 MAPK and NFkB pathways were activated by these stimuli in fibroblasts and osteoblasts, but the kinetics of this activation varied in each cell type and with the nature of the stimulation. E. coli LPS was a stronger inducer of RANKL mRNA in fibroblasts, whereas LPS from P. gingivalis downregulated RANKL mRNA in periodontal ligament cells but increased its expression in osteoblasts. IL-1β induced RANKL in both cell types and without a marked effect on OPG expression. p38 MAPK was more relevant than NF-kB for the expression of RANKL and OPG in these cell types.

Circulação de textos midiáticos entre alunos de escola pública básica

The text characterizes the reading of media-related materials by students of the public basic education system in the State of São Paulo, based on a systematic observation of the circulation of press texts within the school daily life. In a study carried out during two academic years with groups of students from fundamental and secondary education classes belonging to two different schools situated in the outskirts of a town in the interior of the state, the students' reports on their appropriation of media-based information obtained from a variety of sources were analyzed, with particular emphasis on written newspapers. During the period investigated individual and group interviews, as well as texts produced by the students, were taken as points of departure for the analysis. Among the aspects noted from the contact with communication media is the establishment of press information inside the school, albeit with fragmentary repercussions, not fully integrated into the pedagogical daily life, but somewhat circumstantial in the students' lives. The themes that receive more attention circulate through the television, mediated by family or peers, but not by teachers. A proposal for the analysis of these data is made, followed by concrete suggestions as to the treatment to be given to support material, texts and media-based issues at school, taking into account the resources available and the school context such as it appears nowadays.

Identificação de bactérias do filoplano de citros capazes de interromper o quórum sensing em Xanthomonas citri subsp. citri

Pós-graduação em Microbiologia Agropecuária - FCAV

Melatonin attenuates the TLR4-mediated inflammatory response through MyD88-and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Down-regulation of SLC8A1 as a putative apoptosis evasion mechanism by modulation of calcium levels in penile carcinoma

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)