O papel do Estado na proteção aos direitos da criança e do adolescente no Brasil: as especificidades da Constituição Federal, do Estatuto da Criança e do Adolescente e da Lei de diretrizes e Bases da Educação

Pós-graduação em Educação - FFC

Bases fisiológicas para a conservação a longo prazo de sementes Cariniana legalis (Mart.) O. Kuntze

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Desenvolvimento de pastilhas cerâmicas à bases de Si3N4 para aplicações tribológicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito do reembasamento da ciclagem mecânica e da desinfecção por microondas sobre a força máxima de fratura, deformação, energia de ruptura e estabilidade dimensional de bases de prótese

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Lei de Diretrizes e Bases da Educação Nacional: verificando sua aplicabilidade no cotidiano escolar

Este artigo tem como objetivo apresentar ao leitor a síntese de um estudo que compara a realidade de escolas do ensino fundamental, verificando as determinações da lei n.º 9394/96 e suas condições de aplicação envolvendo análise de dados teóricos e observações em campo empírico referentes a aspectos como aplicação de recursos financeiros, implementação de novas propostas pedagógicas, atuação de organismos multilaterais e formação profissional dos professores.

Extração de conhecimento em bases de dados espaciais: algoritmo CHSMST+

Pós-graduação em Ciência da Computação - IBILCE

Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A(2)-like from Bothrops brazili venom

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mediação como processo semiótico: em busca de bases conceituais

In the context of the studies in the Information Science, the information not just depends on meaning, but the social bows are current of this. The research in development analyse conceptual elements to answer the question about the semiotic foundations of the information mediation processes. This paper aim to know and analyse the semiotic foundations of the information mediation processes in the Information Science context. It presents concepts and reflections regarding the relationship of the information mediation process Charles Peirce's Semiotics, especially, the discussion about the semiotic bases to information mediation process. It discusses the information mediation as a specialization of the communication process, developed, fundamentally, for the human action trying to solve communication and technical problems in sociocultural order.

2 '-Deoxyguanosine, 2 '-deoxycytidine, and 2 '-deoxyadenosine adducts resulting from the reaction of tetrahydrofuran with DNA bases

A recent study showed that tetrahydrofuran (THF), a widely used solvent, is carcinogenic in experimental animals. Despite its carcinogenic activity, there is a paucity of information regarding cellular toxicity, biomolecular damage, and genotoxicity induced by THF. We describe here the structural characterization of adducts produced by the reaction of oxidized THF with 2'-deoxyguanosine (dGuo-THF 1 and dGuo-THF 2), 2'-deoxyadenosine (dAdo-THF), and 2'-deoxycytidine (dCyd-THF). Adducts were isolated from in vitro reactions by reverse-phase HPLC and fully characterized on the basis of spectroscopic measurements. The stable derivatives obtained by the reduction of adducts with NaBH4 ( the case of dGuo-THF 1, dCyd-THF, and dAdo-THF) and the stable adduct dGuo-THF 2 were used as standards for optimization of chromatographic separations for adduct detection in DNA through HPLC/ESI/MSMS. Using this methodology, we successfully detected the four adducts in calf thymus DNA reacted with oxidized THF. The present study also provides evidence that rat liver microsomal monooxigenases oxidize THF to the reactive electrophilic compounds that are able to damage the DNA molecule, as indicated by a significant increase in adduct dGuo-THF 1 level when NADPH was added to the THF/ microsomes/dGuo incubation mixtures. Our data point to DNA-THF adducts as possible contributing factors to the toxicological effects of THF exposure.

A NEURAL NET FOR EXTRACTING KNOWLEDGE FROM NATURAL-LANGUAGE DATA-BASES

The present paper introduces a new model of fuzzy neuron, one which increases the computational power of the artificial neuron, turning it also into a symbolic processing device. This model proposes the synapsis to be symbolically and numerically defined, by means of the assignment of tokens to the presynaptic and postsynaptic neurons. The matching or concatenation compatibility between these tokens is used to decided about the possible connections among neurons of a given net. The strength of the compatible synapsis is made dependent on the amount of the available presynaptic and post synaptic tokens. The symbolic and numeric processing capacity of the new fuzzy neuron is used here to build a neural net (JARGON) to disclose the existing knowledge in natural language data bases such as medical files, set of interviews, and reports about engineering operations.

Variabilidade genética e filogeografia de populações de Prochilodus lineatus (Pisces: prochilodontidae) das bacias dos rios Paraguai-Paraná e da bacia Amazônica: bases para programas de conservação e de psicultura

A espécie Prochilodus lineatus, considerada um migrador por excelência, possui intensa ocorrência durante a migração reprodutiva. São peixes de elevado valor econômico e a sua adaptação em cativeiro os tornam altamente interessantes para desenvolvimento de programas de piscicultura. O monitoramento regular das variações genéticas nos estoques é importante em programas de conservação, evitando o declínio da variabilidade genética, essencial para a conservação das espécies. No entanto, os poucos dados moleculares populacionais para Prochilodus lineatus justificam a presente proposta. Nesse sentido, tivemos como objetivo caracterizar a variabilidade genética e estabelecer as relações filogeográficas entre 6 populações de P. lineatus das bacias dos rios Paraguai (2 do rio Paraguai e 3 do rio Cuiabá, MT) e Paraná (1 do rio Mogi-Guaçu, SP), num total de 34 indivíduos. Outros 16 indivíduos dos rios: da Prata, Uruguai, Paraná, Bermejo, Paraguai, Amazonas e Madeira, cujas sequências foram obtidas do National Center for Biotechnology Information (Genbank), foram analisados, totalizando assim, 50 indivíduos. Como grupo externo foi utilizado Salminus brasiliensis. O estudo foi realizado através das análises das sequências do gene mitocondrial ATPase 8/6. O interesse do uso de um gene mitocondrial está na vasta literatura que esse possui em análises filogenéticas e na confiança que existe nos dados gerados de tais análises. O gene citado foi completamente sequenciado (842pb), as análises filogenéticas foram conduzidas pelos métodos “Neighbor Joining (NJ)”, “Minimum Evolution (ME)” e “Máxima Parcimônia (MP)”, com 1000 réplicas de bootstrap no programa MEGA 5.0. Para análises filogeográficas as sequências foram analisadas no programa TCS e no programa Arlequin. Os resultados auxiliarão em uma melhor compreensão da história evolutiva, migração... (Resumo completo, clicar acesso eletrônico abaixo)

Bases Científicas da Acupuntura

Acupuncture is a technique belonging to traditional Chinese medicine that has existed for over 3000 years. It consists of stimuli by pressure, needling, heat and electrical stimulation of the skin at specific points to restore the health of patients. This technique has been increasingly incorporated into the West and therefore the research explaining its various mechanisms become very important to translate these ancient skills. This article is a literature review summarizing the basic concepts, historical and local, anti-inflammatory and neurological effects acupuncture in the body

Bases para criação de um Centro de Voluntariado na UNESP - Guaratinguetá

Volunteering is seen as a form of citizen participation enabling to involve, mobilize, engage and articulate people and institutions around issues of collective interest. Both for the volunteer and for the community involved, voluntary action can promote learning, new experiences and interaction with people previously unknown, as well as create opportunities for professional and personal growth. (CENTRO DE VOLUNTARIADO DE SÃO PAULO, 2012). This work starts from a survey conducted in 2006 by Carvalho, who detected the interest of members of the campus community Guaratinguetá UNESP in performing volunteer work. Its objective is to continue the work mentioned and think of ways to support volunteering in the Guaratinguetá Engineering College, mainly through the creation of connections between stakeholders (individuals and institutions). For this, focused Volunteer Centers and their functional models. Such a center could be the ideal facilitator of relationships between volunteer candidates that integrate FEG / UNESP community and institutions interested in the collaboration of these people. The work highlighted the benefits that voluntary action can bring to those involved in it, and the role that a Volunteer Center at UNESP Guaratinguetá may play, in the promotion and expansion of social activities already undertaken. The study also indicates the need for a validation of the proposals presented here and later detailing way of acting of the Centre in its institutional placement and maintenance costs

Proposta para a implantação de uma trilha interpretativa com bases na Pedagogia Waldorf na Floresta Estadual Edmundo Navarro de Andrade - Rio Claro, SP

At a time when people turn increasingly to technological innovations and virtual networks, a closer interaction with the environment can provide sensitizing experiences. One tool that facilitates this approach is the interpretative trail: its use in a Unit of Conservation (UC) allows more contact between the visitor and the nature elements. This research aimed to propose the establishment of an interpretative trail at the State Florest “Edmundo Navarro de Andrade” (FEENA) in Rio Claro (SP) with theoretical bases from Waldorf Pedagogy. The proposed trail is destined for students with 07-14 years-old, a period that the awareness is more accurate in a person, according to Waldorf tenets. On the path of the trail, we propose some educational activities at the points of interpretation: storytelling about environment; “photograph” the place with a drawing; create a song with sounds produced by the body and by nature elements; blindfold guide and a circle of people to share experiences. The activities aim to provide in the student a close and harmonious contact with oneself, with other people and with the natural world, and also serve as a support for programs of public use and environmental education at UC. The environmental awareness process in the context of FEENA - which has a significant landscape valuation - develops through the sensibilities of exterior and interior world. And also develops with the creation if images, thoughts, feelings and interdependencies relationships. Therefore, the ecologic education allows changes and formation of values and sensitive attitudes to students about the environment