85 resultados para VICINITY


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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is likely the stimulus for osteoclast differentiation. To elucidate the effect of both, shared mouse bone marrow precursor myeloid blast was pre-cultured with M-CSF on plastic and on bone. M-CSF priming prior to stimulation with M-CSF and osteoclast differentiation factor RANKL resulted in a complete loss of osteoclastogenic potential without bone. Such M-CSF primed cells expressed the receptor RANK, but lacked the crucial osteoclastogenic transcription factor NFATc1. This coincided with a steeply decreased expression of osteoclast genes TRACP and DC-STAMP, but an increased expression of the macrophage markers F4/80 and CD11b. Compellingly, M-CSF priming on bone accelerated the osteoclastogenic potential: M-CSF primed cells that had received only one day M-CSF and RANKL and were grown on bone already expressed an array of genes that are associated with osteoclast differentiation and these cells differentiated into osteoclasts within 2 days. Osteoclastogenesis-insensitive precursors grown in the absence of bone regained their osteoclastogenic potential when transferred to bone. This implies that adhesion to bone dictates the fate of osteoclast precursors. Common macrophage-osteoclast precursors may become insensitive to differentiate into osteoclasts and regain osteoclastogenesis when bound to bone or when in the vicinity of bone. J. Cell. Physiol. 229: 210-225, 2014. (c) 2014 Wiley Periodicals, Inc.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Applications of ultrasound were starting from 1912 with the primary objective the detection of icebergs on prevention of maritime accidents. Algae, fish deaths and destruction were observed in the vicinity of sonar that equipped ships and submarines during the First World War.The evolutions of research and studies with ultrasound have big advances following the discovery of piezoelectric transducers in science and technology. As an example we can mention its application in microsurgery, fatigue detection in aerospace mechanics, catalysis sonochemical, biotechnology and others.The work presented here aims to demonstrate the application of ultrasonic in pulsed mode beams in biotechnology with the aim of improving the fermentation of a culture broth containing biological agents. In these experiments we used as ultrasound equipment and oscilator Sonics VCX-600 (20KHz), probe type wave guide. The experiments were conducted in a glass reactor of 200 mL of biomaterial containing cane juice and Saccharomyces cerevisiae in suspension. The parameters analyzed were related to the content Alcohlic (FID gas chromatography), and cell viability (Neubauer chamber), TRS (refractometry). Analysis of results showed that the total production exceeded in irradiated samples compared to normal fermentation (without ultrasound), suggesting additional advantage of ultrasound activation. Lastin Trials 1400 min, showed ethanol production systems 12% more than non-enabled systems. In this context alternatives for ethanol production, bio fuel and many other byproducts of the alcohol industries and chemicals could benefit from the use of ultrasound beams in this range of frequencies.

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The Bom Futuro tin deposit is located in Ariquemes, north-central state of Rondônia. Since its discovery in the late 80s, the tin deposit of Bom Futuro has been explored and considered one of the leading Brazilian producers of cassiterite, exploring it mainly in secondary deposits (placers) in the vicinity of the hill Bom Futuro. The primary mineralization occurs in the contacts between quartz veins and pegmatites with the rocks of the hill and its exploitation has been the goal of new studies in the area. These bodies occur in all rock types of the hill, leading edges of hydrothermal alteration with each rock. The focus of the study is the characterization of hydrothermal alteration through the analysis of the edges of pegmatitic veins intruded on each of the main rock types found on the hill Bom Futuro, which are: biotite gneiss, biotite amphibolite, subvolcanic breccia, topaz leucogranite, topaz leucoriolito and micro melassienito porphyry. The analysis and comparison showed familiarities between the edges of alteration encountered, and possible subdivision into three main zones: the inner zone or the vein itself, intermediate zone or transition zone and the change zone where the passage of hydrothermal features to rocks features is gradual. The cassiterite and sphalerite were found scattered in three zones, however in larger quantities in the intermediate zone, near the contact

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As an effect of the imbalance caused by the damming of rivers and pollution, it has been observed a growing aquatic plants infestation in reservoirs for the generation of electricity. In addition to power generation, these sites have also been used for various other purposes, including recreation, attracting water and navigation. Thus it is important to evaluate these water bodies periodically, in order to verify the leading conditions to the growth of algae, plants and other organisms. In this sense, Remote sensing technology can be a valuable tool for mapping and monitoring the occupation of land in the vicinity of the water body and the optical properties of water, to provide subsidies for the effective management of these aquatic environments. This paper aims to perform the monitoring of the occurrence of aquatic plants in Salto Grande Hydropower Reservoir, located in Americana (SP) and, periodically, map the occupation of land in the vicinity of the water body, through multispectral images taken by sensors on the satellites Landsat series in seven consecutive years: 2004, 2005, 2006, 2007, 2008, 2009 and 2010. The adopted methodological procedure included the images data and the classification of multispectral images to map, every year, the location and extension of the area infested by aquatic plants and the occupation of land

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In most brazilian cities, urban growth has occurred without adequate planning. Consequently, portions of the city were being occupied, often areas unfit for use and occupation of land, causing risks to local residents and decline of urban environmental quality. One of the most frequent problems is the riverbank occupation, causing the deforestation of the riparian vegetation. Given the above, this paper aimed to map the urban sprawl of Rio Claro/SP, as well as riparian vegetation in the vicinity of Corumbataí in the area including the urban area. For this purpose, GIS techniques were used in order to prepare the thematic map of urban expansion, as well as a map of the riparian vegetation through interpretation of aerial photographs in the environment of ARCGIS. From the maps, an analysis of “Plano Diretor” was made in order to verify if the current occupation of urban land meets the stipulations of this legal instrument

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This paper proposes to assess the lability of complexes of uranium in soil using the technique of Diffusion in Thin Films by concentration gradients (DGT) in the vicinity the Osamu Utsumi mine, located in the municipality of Caldas - MG. The technique is based on the 1ª Fick Law, where metal complexes diffuse through a gel, which in turn is adsorbed on a resin. The metals adsorbed are recovered by an analytical technique and quantified by optical emission spectrometer with plasma inductively coupled (ICP-OES) or mass spectrometry with inductively coupled plasma (ICP-MS)

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On November 26 th, 2005, Rhea, one of Saturn's moons, is found by Cassini spacecraft approximately at 5.105 km from Saturn. Observations in situ reveal that electrons are depleted in the moon's vicinity. However, Rhea is considered massive enough to retain a thin atmosphere. Assumption was that the atmosphere of Rhea was not composed exclusively of gas, its likely contains solid material that can absorb magnetospheric particles. According to Jones et al. (2008), these particles were in a speci c position so that at the moment of observation the electrons could not be detected. In opposition to this idea there is a group, Tiscareno et al. 2010, Cornell University Library, that underwent intensive search for any material that might be orbiting Rhea using Cassini images, however the could not identify any. Second recommendation made by American researchers and other countries, and accepted by the National Board of Research the Cassini Equinox Mission will continue in orbit around Saturn until 2016.The probe will perform several maneuvers with high inclination to delve into the main ring system, and then enter in Saturn's atmosphere and collide with planet. This research is of great importance because until today no rings were found orbiting satellites. The goal of this work is to analyze the orbital evolution of a set of particles around Rhea disturbance of Saturn, J2 e J4 and check results by the numerical simulations and the possibility of a stable ring orbiting Rhea.

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A growing number of applications are calling for compact laser sources operating in the mid-infrared spectral region. A review of our recent work on monolithic fiber lasers (FL) based either on the use of rare-earth fluoride fibers or on Raman gain in both fluoride and chalcogenide glass fibers is presented. Accordingly, an erbium-doped double clad fluoride glass all-FL operating in the vicinity of 3 μm is shown. In addition, we present recent results on the first demonstrations of both fluoride and chalcogenide Raman fiber lasers operating at 2.23 and 3.34 μm, respectively. It is shown that based on this approach, monolithic FLs could be developed to cover the whole 2 to 4 μm spectral band.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)