Assessing melatonin and its oxidative metabolites amounts in biological fluid and culture medium by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A genetic linkage study in Brazil identifies a new locus for persistent developmental stuttering on chromosome 10

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Linguagem narrativa e fluência na síndrome de down: uma revisão

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Tecnologias de Informação e Comunicação no cotidiano dos adolescentes: enfoque no comportamento e na competências informacionais da geração Google

Introduction: Individuals born from the 1990’s to accompany technological change course and learn how to use the technological resources that have access before they even learn to read or write. In this sense, the literature considers the digital natives or even 'Google generation'. However, it has been questioned their skills to identify information needs and seeking and use of information in the most varied environments digital information available on the Web. Objectives: To characterize the behavior of information seeking in everyday life of a group of teenage students from a private school in Marilia, Sao Paulo. Methodology: A qualitative study with 30 adolescent students of a private school in Marilia, Sao Paulo. Data collection was accomplished at first by means of a questionnaire, based on the research of Hughes-Hussell and August (2007), containing questions about age, gender, hobbies and everyday tasks, and issues the use of computers and the internet, which allowed determination of the social, economic and cultural rights of respondents. Results: have focused on the use of Information and Communication Technologies (ICT) to search access and use information. It was suggested that the "Brotherhood of Informatics', an incentive for students to (re) learn the tools of digital communication and make appropriate use of the resources, products and services on the web to search and effective use of information compatible with their needs and that is tied to the ethical and responsible use of technology environments. Conclusions: The results arising from this study will continue through the continuation of the Confraternity of Computing, which became a "thermometer" on the use of digital information environments and the attitude of the students in front of Information and Communication Technologies in the College “Cristo Rei”.

Avaliação do Potencial do Banco de Sementes para Recuperação de Áreas Degradadas

O aproveitamento da serapilheira e do banco de sementes de remanescentes florestais tem se mostrado uma técnica alternativa promissora na restauração de áreas degradadas. O objetivo desse projeto foi avaliar o potencial do banco de sementes e serapilheira de um fragmento Florestal localizado no Município de Guará, SP, visando à restauração de áreas degradadas. Parcelas de 0,5 X 0,5m foram alocadas ao acaso em 40 pontos amostrais, sendo 20 na faixa mais externa (primeiros 5m dos limites do fragmento) e 20 no interior do fragmento. Dentro dos limites de cada parcela (0,25m2) foram coletados a serapilheira e a camada superficial do solo, numa profundidade aproximada de 10 cm. Após a coleta, essa amostra foi transferida para um viveiro, onde o material de cada uma das 40 parcelas foi homogeneizado e dividido em duas porções. Uma porção foi disposta em canteiros expostos a pleno sol e a outra em canteiros sob sombreamento artificial de 70%. Após 8 meses de acompanhamento do projeto, em 5 avaliações, foram registrados 137 morfoespécies pertencentes a 35 famílias. A forma de vida herbácea foi a mais abundante com 61,31 % dos indivíduos, a arbustivo-arbórea representou 12,40%, as lianas 8,03% e as indeterminadas 18,24%. A espécie arbórea Cecropia pachystachya (Urticaceae) foi a mais abundante dentre todas as formas de vida, com 27,36% do total. Os tratamentos apresentaram diferenças sutis em relação à riqueza das diferentes formas de vida. No geral, o material das áreas de borda e interior não apresentaram diferenças significativas em relação ao número de indivíduos germinados. Porém, diferenciaram-se em relação as porcentagens de indivíduos germinados nas diferentes formas de vida, com destaque para gramíneas, ciperáceas e lianas nas parcelas de borda. É possível utilizar o banco de...(Resumo completo, clicar acesso eletrônico abaixo)

Geometrical coupling fields of a hypercomplex type

This paper presents an application of Laplace's equation obtained from a quaternionic function that satisfies the Cauchy-Riemann conditions determined earlier by Borges and Machado [#!BorgesZeMarcio!#]. Therefore, we show that it is possible to express in a single equation gravity, electric and magnetic potential fields, and this expression can only be provided due to a function that will be called here the coupling function.

Geometrical hypercomplex coupling between electric and gravitational fields

The present work shows a coupling of electrical and gravitational fields through Cauchy-Riemann conditions for quaternions present in a previous paper [1]. It is also obtained an extended version of the Laplace-like equations for quaternions, now written in terms of both electric and gravitational fields.

Hydroxyapatite and a new fibrin sealant derived from snake venom as scaffold to treatment of cranial defects in rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Gravidez na adolescência: determinante para prematuridade e baixo peso

Prematurity and low birth weight are public health problems. This paper aims to relate the occurrence of premature labors and low birth weight with adolescent pregnancy. We performed a literature review about the socioeconomic and cultural conditions of adolescent pregnancy and perinatal results. Through bibliographical data, we identified observational and systematic review articles that deal with the subject. The literature analysis permits us to conclude that adolescent pregnancies as well as the socioeconomic and cultural environment in which the young mother is inserted are associated with the increased frequency of prematures and low birth weight babies. The development and the implementation of effective public policies directed to that population are necessary to a better approach of the problem.

Avaliação da adequação da ocupação do solo em áreas de preservação permanente (APPs)

Evaluation and adequacy of land occupation in Permanent Preservation Areas (PPAs) are important to ensure quantity and quality of water and local biodiversity. The objective of the study was mapping PPAs according to the Brazilian Forest Code and quantifying land cover and use, establishing the conflict of PPAs occupation in the Ribeirão Lavapés sub watershed. The area is 11,154.58 ha, and is located in Botucatu city, Midwestern region of São Paulo state. For this reason, geoprocessing tools, such as Remote Sensing and the Geographic Information System (SIG) were used. The dominant classes of land use and cover were the Urban Zone in Reverse Cuesta, 4,394.27 ha (39.39%) and Annual Crops in the Peripheral Depression, 3,670.89 ha (39.39%). The mapped area of native forest vegetal cover in the sub watershed was of 1,109.70 ha. Regarding the mapping of PPAs, considering the total area of 1,721.80 ha, a total of 532.15 ha (30.91%) are covered by Riparian Forest and 1,189.65 ha (69.09%) had no native riparian vegetation, therefore, requiring its reforestation.

Efeitos do treinamento aeróbio intervalado periodizado sobre os parâmetros antropométricos, bioquímicos e clínicos em portadores de síndrome metabólica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Alterações na produtividade e composição nutricional de uma pastagem após segundo ano de aplicação de diferentes doses de cama de frango

The objective was to evaluate the potential use of poultry litter, compared to mineral fertilization, productivity, features bromatologic and absorption of nutrients from a pasture of Brachiaria decumbens. The experimental area was installed in oxisoil in Uberlandia-MG. The design was randomized blocks with four replicates and the treatments used: control (without application of organic or mineral source), mineral fertilizer (60, 75 and 100 kg ha(-1), P K, respectively); organic fertilization with poultry litter at rates of 3,125, 6,250, 9,375 and 12,500 kg ha(-1). There were two cuts of the aerial part of Brachiaria decumbens, both at 60 days after treatment. We evaluated the yield of DM and the levels of CP, NDF, ADF, lignin, macro and micronutrients in shoots of grass. The results showed that application of poultry litter increased the productivity of DM and the levels of CP, N, P, K and Zn in Brachiaria decumbens. The poultry litter can be used as supplementary source of nutrients, the mineral fertilizer. The use of poultry litter not increased over the levels of S, Ca and Mg in Brachiaria decumbens.

Dog culling and replacement in an area endemic for visceral leishmaniasis in Brazil

Measures employed to control visceral leishmaniasis in Brazil have focused on vector control by residual insecticide spraying and diagnosis of infection with elimination of positive dogs. We describe dog culling and replacement in a Brazilian endemic area (the Alvorada District, Aracatuba, SP) in order to better understand dog population dynamics when elimination of the dog reservoir is adopted as the main control measure. From August 2002 to July 2004, 60.9% of the estimated dog population for the area was culled with a mean age of 34 months old. The presence of anti-Leishmania sp. antibodies was recorded for only 26.7% of the euthanized canines. Replacement was observed in 38.8% of the cases, some of them by 2 or more dogs and in a mean time of 4 months. Dogs were replaced mostly by puppies of both sexes with a mean age of 6.8 months. From August 2002 to April 2005 we were able to follow-up 116 of these dogs, during a mean time of 8.7 months. Canine visceral leishmaniasis seropositivity by ELISA was observed in 42.2% of the followed dogs, 30.6% of which were already positive at the first evaluation. By the end of the follow-up period 37% of the dogs were submitted to euthanasia, with a mean age of 18.3 months. In the studied CVL endemic area of Brazil, euthanasia and the subsequent replacement ratio were high, increasing the dog population turnover and leading to a younger population that might be more susceptible to a variety of other infectious diseases in addition to CVL. Dog culling as a control strategy for VL should be reassessed. (C) 2008 Elsevier B.V. All rights reserved.

Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool

PURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.