Novas abordagens sobre tratamentos da Leishmaniose tegumentar

De acordo com a Organização Mundial da Saúde, a leishmaniose é ainda uma das doenças mais negligenciadas do mundo, afetando principalmente países pobres e em desenvolvimento. As leishmanioses podem, de acordo com a forma de acometimento do homem, dividir-se em dois grandes grupos: visceral e tegumentar. As estatísticas mostram que cerca de 350 milhões de pessoas são consideradas com risco de contrair leishmaniose, e cerca de dois milhões de novos casos ocorrem anualmente. O número de casos de leishmaniose tegumentar no Brasil em 2011 foi de 15.731. É considerada uma doença negligenciada uma vez que os fármacos de escolha são preparações à base de antimoniais, sendo os mesmos desde sua descoberta em 1912. Além disso o tratamento é longo, doloroso e altamente tóxico, assim levando os pacientes muitas vezes a desistirem antes do término previsto. O presente trabalho tem como objetivo fazer uma revisão bibliográfica a partir do banco de dados do PubMed e Scielo sobre novas pesquisas na área de fármacos e novos tratamentos para leishmaniose cutânea entre os anos de 2007 e 2012.

Explorando abordagens de aprendizado sequencial para floresta de caminhos ótimos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Explorando abordagens de múltiplos rótulos por floresta de caminhos ótimos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O modelo atômico de Bohr e as abordagens para seu ensino na escola média

The teaching of modern and contemporary Physics subjects in high school is indispensable and it was already justified by several researchers. Among the subjects which must be taught, there is, for instance, Bohr atomics model. However, as it was noticed in literature review, many didactic materials do not deal with this model adequately, since that they do not take into account Bohr ideas, which involved Planck studies on black-body radiation, Einsten theory for photoelectric effect, Rutherford experiences and atomics model and the empiric results upon the spectrums of chemical elements emission. From that, it is extremely important teaching through approaches which potentialize the learning of the model proposed by Niels Bohr. On the other hand, teachers from high schools cannot have clearness about which approaches can be applied for teaching the mentioned model. Thus, it is presented some possibilities for teaching Bohr atomics model, with examples and justifications for the use of each one. Special treatment was attributed to the teaching from Science History and Philosophy, from the reading of scientific diffusion and original scientific texts, from analogies, from comic strips and from computer simulations.

Estratégias de seleção de genótipos de soja por meio de modelos mistos e abordagens multivariadas

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Equações de Painlevé mistas e modelo PIII-PV simétrico

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Formação inicial de professores de ciências: reflexões a partir das abordagens das estratégias de ensino e aprendizagem em um curso de licenciatura

We developed a case study aimed to identify and to analyze how the approach to teaching and learning strategies occurs in a science teaching degree course and what are the possible influences of this formation on the pedagogical practice of these educators. The analysis focused on documents, questionnaires and interviews with lecturers and students. There is reduced diversity of strategies in the disciplines of the specific area, with prevalence of expository classes and of laboratory, and the lecturers seem to believe that a good knowledge of specific content is enough for teaching. Despite that pedagogical disciplines do explore diverse practices, many students incorporate the academic view prevailing in the course, repeating the model of their lecturers. We stress the need for initial teacher training to take into account both aspects, the domain of the specific contents and the best ways to mediate them, forming intellectuals able to discuss and to redraw their educative actions in a perspective of transformation of the reality.

O lugar da gramática nas diferentes abordagens ao ensino de inglês

Considering the fundamental importance of grammar in any modern language teaching proposal, the aim of this paper is to discuss how the different approaches to the teaching of English as a foreign language (EFL) have considered the role of grammar and the consequences to its teaching.

Determinação molecular da viabilidade do Mycobacterium leprae: uma comparação com outras abordagens metodológicas

Pós-graduação em Doenças Tropicais - FMB

Verificação da eficiência do modelo de Mohler na resposta do comportamento de vigas mistas de madeira e concreto

The aim of this research study was to evaluate the structural behaviour of the wood and concrete composite system for bridge decks with emphasis on the metal shear connectors. Experimental tests were performed on composite specimens and wood and concrete beams with a metallic connector system in an X position, using CS100900-type screws. All specimens and beams were submitted to static loads until failure in order to obtain the strength and stiffness of the connection system. The experimental results for the stiffness of the beams were compared with the analytical results obtained through the Mohler model, presenting good equivalence for service loads. The experimental results obtained demonstrate that the most significant damage in composite systems occurred in the connectors' areas.

Abordagens estatísticas em testes de resistência de união entre dentina bovina, sistema adesivo e resina composta

Pós-graduação em Odontologia Restauradora - ICT

Aplicações médicas das abordagens complexas não lineares: a geometria fractal do EEG

Pós-graduação em Saúde Coletiva - FMB

Estudo comparativo de restos fósseis e recentes de Amphisbaenia: abordagens filogenéticas, paleoecológicas, paleobiogeográficas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Abordagens periodontais na promoção da harmonia do sorriso

Several therapeutic approaches have been proposed in order to achieve an esthetically pleasing and harmony smile. The present study reports a case in which gingivectomy was performed in the region of the upper anterior teeth combined with osteotomy in the region of the upper posterior teeth and removal of the superior labial frenum to promote harmony smile by decreasing the gummy smile and adequacy of buccal corridor. Osteoplasty gingivoplasty, and frenectomy procedures were planned and performed in a single session. The extraction of the maxillary third molars was also performed in order to avoid postoperative complications. Follow-up visits were performed at 7, 15, 30 and 180 days postoperatively. At 7 days, the gingival tissue was in the initial process of healing, demonstrating inflammation still in evidence. At 15 days, the gingival tissue was found in the final healing process, showing characteristics of normal health gum. At 30 days, there was complete healing of gingival tissues without clinical exposure of the root surfaces. After 180 days, tissues remained in healthy, demonstrating the success of the treatment. Patient showed complete satisfaction with the results. It can be concluded that, when properly indicated, the combination of gingivectomy, osteotomy and frenectomy procedures are promising therapeutic approaches for promoting harmony smile.