Análise de propriedades topológicas das redes biológicas integradas da Escherichia coli e da Saccharomyces cerevisiae

Biological processes are complex and possess emergent properties that can not be explained or predict by reductionism methods. To overcome the limitations of reductionism, researchers have been used a group of methods known as systems biology, a new interdisciplinary eld of study aiming to understand the non-linear interactions among components embedded in biological processes. These interactions can be represented by a mathematical object called graph or network, where the elements are represented by nodes and the interactions by edges that link pair of nodes. The networks can be classi- ed according to their topologies: if node degrees follow a Poisson distribution in a given network, i.e. most nodes have approximately the same number of links, this is a random network; if node degrees follow a power-law distribution in a given network, i.e. small number of high-degree nodes and high number of low-degree nodes, this is a scale-free network. Moreover, networks can be classi ed as hierarchical or non-hierarchical. In this study, we analised Escherichia coli and Saccharomyces cerevisiae integrated molecular networks, which have protein-protein interaction, metabolic and transcriptional regulation interactions. By using computational methods, such as MathematicaR , and data collected from public databases, we calculated four topological parameters: the degree distribution P(k), the clustering coe cient C(k), the closeness centrality CC(k) and the betweenness centrality CB(k). P(k) is a function that calculates the total number of nodes with k degree connection and is used to classify the network as random or scale-free. C(k) shows if a network is hierarchical, i.e. if the clusterization coe cient depends on node degree. CC(k) is an indicator of how much a node it is in the lesse way among others some nodes of the network and the CB(k) is a pointer of how a particular node is among several ...(Complete abstract click electronic access below)

Investigação sobre a construção das noções espaço-geométricas por alunos da educação infantil

This research aims to understand how students of Early Childhood Education (considering the range of 2-3 years) build the space - geometric notions from the interaction established with the school routine. The venue was a municipal school Miners Tietê, within the State of São Paulo. The interest in this research took place from two reasons: the first because of course taken “Mathematics in Early Childhood Education” and the second stemmed from my professional work in a school for early childhood education. This research is initially composed by bibliographic studies concerning the topic and was grounded in a qualitative interpretive approach, aiming to investigate the psychological process of building space - geometric notions in children. The procedures used in the initial research to collect data were interviews using the method of clinical type and Piagetian tests. Thus allows us to understand the construction of the geometric space by children in their topological, projective and Euclidean relations

Estudo da tecnologia e processos de extração em poços de petróleo

The analysis of the extraction process in oil wells is presented exploring the challenges to the effectiveness of the procedure is shown step by step in the process. There is an analysis of the major tools and equipment needed in the drilling process, promoting the understanding of the challenges in the pre-salt layers, compared to conventional processes. The work is reinforced through studies of the influence of the corrosive compared not corrosive environment in drill strings

Sobre o teorema de fibração de Milnor

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Quantum Aspects of Solitons and Deformations on Ad'S IND. 4'x C'P POT.3' ('S POT. 7')

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Soluções do tipo vórtice em um modelo de Maxwell-Chern-Simons-Higgs com campos de Gauge distintos

Pós-graduação em Física - FEG

Propostas de modelagem matemática para o problema de restauração de sistemas de distribuição de energia elétrica radiais

Pós-graduação em Engenharia Elétrica - FEIS

Fractais de Rauzy, autômatos e frações contínuas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Máquinas de somar estocásticas e conjuntos de Julia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A survey on the set of periods of the graph homeomorphisms

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A class of cubic Rauzy fractals

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

On the N=4, d=4 pure spinor measure factor

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Open-closed superstring amplitudes using vertex operators in AdS(5) x S-5

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Infinite tension limit of the pure spinor superstring

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Spectrum generating algebra for the pure spinor superstring

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)