31 resultados para Suppression tumorale


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Phase separation suppression due to external biaxial strain is observed in InxGa1-xN alloy layers by Raman scattering spectroscopy. The effect is taking place in thin epitaxial layers pseudomorphically grown by molecular-beam epitaxy on unstrained GaN(001) buffers. Ab initio calculations carried out for the alloy free energy predict and Raman measurements confirm that biaxial strain suppress the formation of phase-separated In-rich quantum dots in the InxGa1-xN layers. Since quantum dots are effective radiative recombination centers in InGaN, we conclude that strain quenches an important channel of light emission in optoelectronic devices based on pseudobinary group-III nitride semiconductors. (C) 2002 American Institute of Physics.

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A pon stimulation by contralateral, ipsilateral or bilateral noise, the medial olivocochlear efferent tract changes the amplitude of otoacoustic emissions relative to the tested ear, reducing or removing it; this resulted in a reduction/suppression effect of otoacoustic emissions. Differences in patterns of elimination/reduction of otoacoustic emissions between ears have been documented worldwide; there are, however, no Brazilian studies investigating the effect of lateral dominance.Aims: To compare the effect of the presence of deletion/reduction of otoacoustic emissions and their amplitude relative to lateral dominance in normal hearing adults.Methods: A clinical and experimental study. The sample comprised 75 individuals. The methodology was conventional - linear click intensity of 60 dB SPL; white noise was contralateral stimulation at 60 dB SPL.Description of results: There were no statistically significant differences between right and left ear results, in terms of asymmetry of the degree of otoacoustic emissions and the presence of suppression/reduction.Conclusion: There is no lateral dominance in the degree of otoacoustic emissions in the presence of suppression/reduction in the study population.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Flutter is an in-flight vibration of flexible structures caused by energy in the airstream absorbed by the lifting surface. This aeroelastic phenomenon is a problem of considerable interest in the aeronautic industry, because flutter is a potentially destructive instability resulting from an interaction between aerodynamic, inertial, and elastic forces. To overcome this effect, it is possible to use passive or active methodologies, but passive control adds mass to the structure and it is, therefore, undesirable. Thus, in this paper, the goal is to use linear matrix inequalities (LMIs) techniques to design an active state-feedback control to suppress flutter. Due to unmeasurable aerodynamic-lag states, one needs to use a dynamic observer. So, LMIs also were applied to design a state-estimator. The simulated model, consists of a classical flat plate in a two-dimensional flow. Two regulators were designed, the first one is a non-robust design for parametric variation and the second one is a robust control design, both designed by using LMIs. The parametric uncertainties are modeled through polytopic uncertainties. The paper concludes with numerical simulations for each controller. The open-loop and closed-loop responses are also compared and the results show the flutter suppression. The perfomance for both controllers are compared and discussed. Copyright © 2006 by ABCM.

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In this work the chaotic behavior of a micro-mechanical resonator with electrostatic forces on both sides is suppressed. The aim is to control the system in an orbit of the analytical solution obtained by the Method of Multiple Scales. Two control strategies are used for controlling the trajectory of the system, namely: State Dependent Riccati Equation (SDRE) Control and Optimal Linear Feedback Control (OLFC). The controls proved effectiveness in controlling the trajectory of the system. Additionally, the robustness of each strategy is tested considering the presence of parametric errors and measurement noise in control. © 2012 American Institute of Physics.

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Common Bean (Phaseolus vulgaris L.) is widespread in the social and economic scene in Brazil, as well it is Brazilian population main dish, and it also helps small and medium farmers' income. The objective of this study was to compare the productivity performance of common bean Carioca - IAC Alvorada with irrigation suppression in each of the five phenological phases. The experiment was conducted in plots in a greenhouse at College of Agronomical Sciences, São Paulo State University (UNESP), Botucatu - SP. The hypothesis is that if the water supply is suppressed in one of the five development stages of irrigated common beans, the yield reduction would be at least 20%. The treatments consisted of suppression irrigation in one of the five development stages (stage V1 to V3, stage V4 to early flowering, flowering stage, pod formation stage and pod filling stage) compared with the irrigation at all stages and suppression of irrigation at all stages, with seven treatments and four replications. The treatments most affected by water suppression were those which suffered suppression of irrigation during the vegetative phase and flowering stage. Treatments with water suppression in all stages, and suppression during the phases (stage V1 to V3, stage V4 to early flowering, flowering stage, pod formation stage and pod filling stage) showed yield reduction of approximately 95%, 55.1%, 49.5%, 63,1%, 30.2% and 35.6%, respectively, when compared to treatment with irrigation all stages. All treatments considered confirmed the hypothesis.

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In this paper the dynamics of the ideal and non-ideal Duffing oscillator with chaotic behavior is considered. In order to suppress the chaotic behavior and to control the system, a control signal is introduced in the system dynamics. The control strategy involves the application of two control signals, a nonlinear feedforward control to maintain the controlled system in a periodic orbit, obtained by the harmonic balance method, and a state feedback control, obtained by the state dependent Riccati equation, to bring the system trajectory into the desired periodic orbit. Additionally, the control strategy includes an active magnetorheological damper to actuate on the system. The control force of the damper is a function of the electric current applied in the coil of the damper, that is based on the force given by the controller and on the velocity of the damper piston displacement. Numerical simulations demonstrate the effectiveness of the control strategy in leading the system from any initial condition to a desired orbit, and considering the mathematical model of the damper (MR), it was possible to control the force of the shock absorber (MR), by controlling the applied electric current in the coils of the damper. © 2012 Foundation for Scientific Research and Technological Innovation.

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The tapping mode is one of the mostly employed techniques in atomic force microscopy due to its accurate imaging quality for a wide variety of surfaces. However, chaotic microcantilever motion impairs the obtention of accurate images from the sample surfaces. In order to investigate the problem the tapping mode atomic force microscope is modeled and chaotic motion is identified for a wide range of the parameter's values. Additionally, attempting to prevent the chaotic motion, two control techniques are implemented: the optimal linear feedback control and the time-delayed feedback control. The simulation results show the feasibility of the techniques for chaos control in the atomic force microscopy. © 2012 IMechE.

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The success of conservation systems such as no-till depends on adequate soil cover throughout the year, which is possible through the use of cover crops. For this purpose the species belonging to the genus Urochloa has stood out by virtue of its hardiness and tolerance to drought. Aiming ground cover for the no-till system, the objective was to evaluate the establishment of two species of the genus Urochloa, in three sowing methods, in the weed suppression and the sensitivity of these forages to glyphosate. The study design was a randomized block with a 2 x 3 x 3 factorial arrangement, in which factor A was composed of Urochloa ruziziensis and Urochloa hybrid CIAT 36087 cv. Mulato II, factor B was formed by sowing methods: sown without embedding, sown with light embedding and sown in rows, and factor C was composed of three doses of glyphosate (0.975, 1.625 and 2.275 kg ha(-1) of acid equivalent). For determination of weed suppression, assessment of biomass yield and soil cover was performed, by brachiaria and weeds, at 30, 60, 90, 120 and 258 days after sowing. Visual assessment of the desiccation efficiency at 7 and 14 days after herbicide application was performed. It is concluded that embedding Urochloa seeds stands out in relation to sowing in the soil surface. Urochloa ruziziensis is more efficient in the dry weight yield, weed suppression, in addition to being more sensitive to glyphosate herbicide.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The present work investigates the nonlinear response of a half-car model. The disturbances of the road are assumed to be sinusoidal. After constructing the bifurcation diagram, we use the 0-1 test to identify chaotic motions. The main objective of this study is to eliminate chaotic behavior of the chassis and reduce its vibrations. To accomplish this, a semi-active vehicle suspension control system, using magneto-rheological dampers, is proposed. The proposed semi-active control strategy consists of two nonlinear control laws: a feedforward control, and a feedback control. They are obtained by considering the SDRE (State Dependent Riccati Equation) control, where the control parameter is the voltage applied to the coils of the magneto-rheological dampers. Numerical results show that the proposed control method is effective in significantly reducing of the chassis vibration, increasing, therefore, passenger comfort.