Detecção molecular do rearranjo Line-1 /c-Myc em tumores venéreos transmissíveis caninos espôntaneos

Transmissible venereal tumor (TVT) is a neoplasia that develops naturally in dogs. It can be easily transplanted, which demonstrates its ability to spread from animal to animal. Since the Linr-1/c-MYC rearrangement in TVT cells had not been studied at the Veterinary Hospital of the Veterinary School, Unesp in Botucatu, SP, this study aimed to detect this genetic alteration specific to this kind of tumor by means of the polymerase chain reaction (PCR). Twenty dogs with cytological diagnosis of TVT were used. Samples of neoplastic cells were collected to determine the presence of the Line-1/c-MYC marker. The rearrangement characterized by 340bp amplicons did not vary, in agreement with previous studies using the same methodology. This contributed to a more precise identification of persistent tumor cells in cases in which gross or microscopical detection was not possible.

Características tomográficas de neoplasias encefálicas primárias em cães

Computed tomography (CT) can be considered an important test to identify the presence of primary brain neoplasias in dogs. CT results can help define the type of brain tumor when associated with clinical findings. It allows the identification of lesions and their features, such as size, location, compression and invasion of adjacent tissue. One must analyze the density, mass effect, peritumoral edema, calcification, and image enhancement after intravenous injection of contrast medium. Gliomas, meningiomas and tumors of the choroid plexus and pituitary are the most common primary brain neoplasms diagnosed by CT in dogs. The aim of this paper is to review the literature related to primary brain tumors and report their most important tomographic features, in order to help clinicians achieve a presumptive diagnosis of tumor type.

As atividades de comércio e serviços do consumo produtivo nas cidades médias brasileiras: Marília-SP e Londrina-PR

Las ramas de actividades comerciales y de servicios, especialmente aquellos relacionados con el sector industrial y sector agroindustrial, tanto que está a cargo de capital extranjero como aquellos gestionados por capital local, pueden ser considerados como responsables de la reestructuración de la ciudad. Este trabajo tiene por objetivo analizar la localización dinámica de los segmentos de actividades de comercio y servicios de consumo productivo que son relevantes para la comprensión de las nuevas relaciones de consumo. Observar las formas de organización de la comercialización de bienes y servicios, y consumo productivo que son representativos de la época actual, considerando los procesos de descentralización y centralización espacial que marcan las estrategias de las empresas en la ciudades medias