Influence of compression forces on tablets disintegration by AC Biosusceptometry

Analysis of physical phenomena that occurs during tablet disintegration has been studied by several experimental approaches; however none of them satisfactorily describe this process. The aim of this study was to investigate the influence of compression force on the tablets by associating the AC Biosusceptometry with consolidated methods in order to validate the biomagnetic technique as a tool for quality control in pharmaceutical processes.Tablets obtained at five compression levels were submitted to mechanical properties tests. For uncoated tablets, water uptake and disintegration force measurements were performed in order to compare with magnetic data. For coated tablets, magnetic measurements were carried out to establish a relationship between physical parameters of the disintegration process. According to the results, differences between the compression levels were found for water uptake, force development and magnetic area variation measurements. ACB method was able to estimate the disintegration properties as well as the kinetics of disintegration process for uncoated and coated tablets. This study provided a new approach for in vitro investigation and validated this biomagnetic technique as a tool for quality control for pharmaceutical industry. Moreover, using ACB will also be possible to test these parameters in humans allowing to establish an in vitro/in vivo correlation (IVIVC). (C) 2007 Elsevier B.V. All rights reserved.

The cross-entropy method and its application to minimize the ripple of magnetic levitation forces of a maglev system

This paper explores firstly the potential of a new evolutionary method - the Cross-Entropy (CE) method in solving continuous inverse electromagnetic problems. For this purpose, an adaptive updating formula for the smoothing parameter, some mutation operation, and a new termination criterion are proposed. The proposed CE based metaheuristics is applied to reduce the ripple of the magnetic levitation forces of a prototype Maglev system. The numerical results have shown that the ripple of the magnetic levitation forces of the prototype system is reduced significantly after the design optimization using the proposed algorithm.

Electromagnetic energy-momentum and forces in matter

We discuss the electromagnetic energy-momentum distribution and the mechanical forces of the electromagnetic field in material media. There is a long-standing controversy on these notions. The Minkowski and the Abraham energy-momentum tensors are the most well-known ones. We propose a solution of this problem which appears to be natural and self-consistent from both a theoretical and an experimental point of view. (C) 2003 Elsevier B.V. B.V. All rights reserved.

Comments on a nonlinear and nonideal electromechanical damping vibration absorber, Sommerfeld effect and energy transfer

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Theoretical Models for Surface Forces and Adhesion and Their Measurement Using Atomic Force Microscopy

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

On the effects of system parameters on the response of a harmonically excited system consisting of weakly coupled nonlinear and linear oscillators

This paper discusses the dynamic behaviour of a nonlinear two degree-of-freedom system consisting of a harmonically excited linear oscillator weakly connected to a nonlinear attachment having linear and cubic restoring forces. The effects of the system parameters on the shape of the frequency-response curve are investigated, in particular those yielding the appearance and disappearance of outer and inner detached resonance curves. In contrast to the case when the linear stiffness of the attachment is zero, it is found that multivaluedness occurs at low frequencies as the resonant peak bends to the right. It is also found that as the coefficient of the linear term increases, the range of parameters yielding detached curves reduces. Compared to the case when the attached system has no linear stiffness term, this range of parameters corresponds to smaller values of the damping and nonlinear coefficients. Approximate analytical expressions for the jump-up and jump-down frequencies of the system under investigation are also derived. (C) 2011 Elsevier Ltd. All rights reserved.

A Transmission Problem for Euler-Bernoulli beam with Kelvin-Voigt Damping

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Built to Bite: Feeding Kinematics, Bite Forces, and Head Shape of a Specialized Durophagous Lizard, Dracaena Guianensis (Teiidae)

Most lizards feed on a variety of food items that may differ dramatically in their physical and behavioral characteristics. Several lizard families are known to feed upon hard-shelled prey (durophagy). Yet, specializations toward true molluscivory have been documented for only a few species. As snails are hard and brittle food items, it has been suggested that a specialized cranial morphology, high bite forces, and an adapted feeding strategy are important for such lizards. Here we compare head and skull morphology, bite forces, and feeding kinematics of a snail-crushing teiid lizard (Dracaena guianensis) with those in a closely related omnivorous species (Tupinambis merianae). Our data show that juvenile D. guianensis differ from T. merianae in having bigger heads and greater bite forces. Adults, however, do not differ in bite force. A comparison of feeding kinematics in adult Dracaena and Tupinambis revealed that Dracaena typically use more transport cycles, yet are more agile in manipulating snails. During transport, the tongue plays an important role in manipulating and expelling shell fragments before swallowing. Although Dracaena is slow, these animals are very effective in crushing and processing hard-shelled prey. J. Exp. Zool. 317A:371381, 2012. (c) 2012 Wiley Periodicals, Inc.

Photoelastic analysis of forces generated by T-loop springs made with stainless steel or titanium-molybdenum alloy

Introduction: The purpose of this study was to use photoelastic analysis to compare the system of forces generated by retraction T-loop springs made with stainless steel and titanium-molybdenum alloy (TMA) (Ormco, Glendora, Calif) with photoelastic analysis. Methods: Three photoelastic models were used to evaluate retraction T-loop springs with the same preactivations in 2 groups. In group 1, the loop was constructed with a stainless steel wire, and 2 helicoids were incorporated on top of the T-loop; in group 2, it was made with TMA and no helicoids. Results: Upon using the qualitative analysis of the fringe order in the photoelastic model, it was observed that the magnitude of force generated by the springs in group 1 was significantly higher than that in group 2. However, both had symmetry for the active and reactive units related to the system of force. Conclusions: Both springs had the same mechanical characteristics. TMA springs showed lower force levels. (Am J Orthod Dentofacial Orthop 2011;140:e123-e128)

Stochastic field processes in the mathematical modelling of damped transmission line vibrations

Wind-excited vibrations in the frequency range of 10 to 50 Hz due to vortex shedding often cause fatigue failures in the cables of overhead transmission lines. Damping devices, such as the Stockbridge dampers, have been in use for a long time for supressing these vibrations. The dampers are conveniently modelled by means of their driving point impedance, measured in the lab over the frequency range under consideration. The cables can be modelled as strings with additional small bending stiffness. The main problem in modelling the vibrations does however lay in the aerodynamic forces, which usually are approximated by the forces acting on a rigid cylinder in planar flow. In the present paper, the wind forces are represented by stochastic processes with arbitrary crosscorrelation in space; the case of a Kármán vortex street on a rigid cylinder in planar flow is contained as a limit case in this approach. The authors believe that this new view of the problem may yield useful results, particularly also concerning the reliability of the lines and the probability of fatigue damages. © 1987.

A demonstration of dry and viscous damping of an oscillating pendulum

Damped oscillatory motion is one of the most widely studied movements in physics courses. Despite this fact, dry damped oscillatory motion is not commonly discussed in physics textbooks. In this work, we discuss the dry and viscous dampec pendulum, in a teaching experiment that can easily be performed by physics or engineering students.

Higgs- and Goldstone-boson-mediated long range forces

In certain mild extensions of the standard model, spin-independent long range forces can arise by exchange of two very light pseudoscalar spin-0 bosons. In particular, we have in mind models in which these bosons do not have direct tree level couplings to ordinary fermions. Using the dispersion theoretical method, we find a 1/r3 behavior of the potential for the exchange of very light pseudoscalars and a 1/r7 dependence if the pseudoscalars are true massless Goldstone bosons. ©1999 The American Physical Society.

Long range neutrino forces in the cosmic relic neutrino background

Neutrinos mediate long range forces among macroscopic bodies in a vacuum. When the bodies are placed in the neutrino cosmic background, these forces are modified. Indeed, at distances long compared to the scale T -1, the relic neutrinos completely screen off the two-neutrino exchange force, whereas for small distances the interaction remains unaffected. ©2000 The American Physical Society.

Transmission problem for waves with frictional damping April 22, 2007

In this paper we consider the transmission problem, in one space dimension, for linear dissipative waves with frictional damping. We study the wave propagation in a medium with a component with attrition and another simply elastic. We show that for this type of material, the dissipation produced by the frictional part is strong enough to produce exponential decay of the solution, no matter how small is its size. ©2007 Texas State University.