Plasma rico em plaquetas no tratamento de lesões condrais articulares induzidas experimentalmente em equinos: avaliação clínica, macroscópica, histológica e histoquímica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Laser treatment of experimentally induced chronic arthritis

In this work, we investigated the effects of He-Ne laser irradiation on the inflammatory process induced in the articular cartilage of the right knee of guinea pigs. Through electron microscopy analysis it was possible to identify the induced arthritis in the articular cartilage and its modification after the laser treatment. The laser radiation promoted a reduction in the proliferation of the inflammatory cells in the damaged tissue and also induced the formation of cartilage bridges that tied the destroyed parts favoring the formation of a repaired tissue in the injured cartilage. (C) 2000 Elsevier B.V. B.V. All rights reserved.

Arthrodesis tarsocrural or tarsometatarsal in 2 dogs using circular external skeletal fixator

An external fixation technique, using a circular fixator, to obtain arthrodesis was evaluated in 2 dogs with infected open lesions and soft tissue damage. In both cases, articular cartilage was curetted, and devitalized bone and necrotic soft tissue were removed. No bone graft was used. The wounds were maintained open and the dogs received postoperative antibiotic therapy. The arthrodesis site was compressed progressively as needed. Infection was eradicated and bony union was obtained in both dogs. It was concluded that the use of a circular fixator is an effective method to achieve arthrodesis.

Ovinos como modelo experimental: estudo do joelho e mensuração dos ângulos tibiais

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeito do implante autólogo de plasma rico em plaquetas (PRP) e células tronco mesenquimais na reparação de lesões condrais articulares induzidas experimentalmente em equinos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cultivo de condrócitos equinos e avaliação de sua condrogenicidade mediante implante de células associadas ao hidrogel em subcutâneo de camundongos atímicos

Pós-graduação em Medicina Veterinária - FMVZ

Avaliação clínica, radiográfica e histopatológia após aprofundamento do sulco troclear e aplicação de grampo metálico: estudo experimental em cães

Pós-graduação em Medicina Veterinária - FMVZ

Cultura de condrócitos para o uso terapêutico: reconstituição de cartilagem

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Degenerative joint disease in cattle and buffaloes in the Amazon region: a retrospective study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ascorbic acid iontophoresis for chondral gain in rats with arthritis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Treatment of osteochondral injuries with platelet gel

OBJECTIVES: Treatments for injured articular cartilage have not advanced to the point that efficient regeneration is possible. However, there has been an increase in the use of platelet-rich plasma for the treatment of several orthopedic disorders, including chondral injuries. Our hypothesis is that the treatment of chondral injuries with platelet gel results in higher-quality repair tissue after 180 days compared with chondral injuries not treated with gel.METHODS: A controlled experimental laboratory study was performed on 30 male rabbits to evaluate osteochondral injury repair after treatment with or without platelet gel. Osteochondral injuries were surgically induced in both knees of each rabbit at the medial femoral condyle. The left knee injury was filled with the platelet gel, and the right knee was not treated. Microscopic analysis of both knee samples was performed after 180 days using a histological grading scale.RESULTS: The only histological evaluation criterion that was not significantly different between treatments was metachromasia. The group that was treated with platelet gel exhibited superior results in all other criteria (cell morphology, surface regularity, chondral thickness and repair tissue integration) and in the total score.CONCLUSION: The repair tissue was histologically superior after 180 days in the study group treated with platelet gel compared with the group of untreated injuries.

Fatores indutores e supressores da eritropoiese em caninos doentes renais crônicos

Pós-graduação em Cirurgia Veterinária - FCAV

A influência da prática de atividade regular na composição corporal de pacientes com osteoartrite

Introduction: Osteoarthritis, osteoarthrosis or degenerative joint disease characterized by progressive loss of articular cartilage, pain, changes in subchondral bone, osteophyte formation and proliferation. Age, bone mineral density, joint instability, excess weight among others, are risk factors. Methods: To check the influence os physical exercise in patients with the disease were evaluated 39 patients over 50 years, both genders, with clinical and / or radiographic osteoarthritis were divided into experimental group (EG) and control group (CG). EG performed regular physical activity (aerobics) three times a week for four months, while CG was submitted to physical therapy painkiller in the same period. We analyzed demographics, BMI, basal metabolic rate and percentage of fat mass. Results: The results showed that regular physical activity reduced the body fat, but because of their characteristics and low-impact aerobics was not observed consistent benefits in muscle component. However, compared with the CG demonstrated a positive impact on other parameters of body composition.

Lesão condral do joelho: comparação entre ressonância magnética e vídeo-artroscopia. Efeito da aplicação do plasma rico em plaquetas

Pós-graduação em Bases Gerais da Cirurgia - FMB

Diferentes terapias na osteoartrite induzida por papaína em joelhos de ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)