286 resultados para Insuficiencia venosa crónica


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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

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Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The real role of renal transplantation in hepatic fi brosis progression caused by hepatitis C virus is still unpredictable. Histological evaluation of the liver is the best form to estimate fi brosis evolution, although semiquantitative analysis carries important limitations. Objective: To apply a morphometric quantitative assay on hepatic fi brosis progression in renal recipients with hepatits C. Methods: Thirty patients were initially evaluated, but only seven were included. They underwent the fi rst biopsy near the transplantation date and the second biopsy at least 4 years later. The immunosuppressant therapy adopted in all cases was azatioprine and micofenolate. Fibrosis progression rate (FPR) was calculated before and after the surgery date in each patient according to Metavir score and morphometric analysis. Results: The FPR calculated by Metavir score showed no statistical difference between pre- and post-transplantation (p=0.9). The FPR calculated by the morphometric analysis was 0.58 ± 0.78 before transplantation and 3.0 ± 3.3 after the surgery, with statistical signi- fi cance between these values (p=0.0026). Conclusion: In the sample assessed, the progression of hepatic fi brosis was documented and quantifi ed only by the morphometric analysis, which is as a promising approach to histological evaluation of these patients.

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Objective: To analyze and correlate the physical activity level (PAL) and the quality of life (QL) in patients with chronic kidney disease (CKD) undergone hemodialyses and to verify in practitioner of physical activity (PPA) if they follow rules and recommendations on their own practice. Methods: The QL (KDQOL-SFTM questionnaire), PAL (IPAQ questionnaire) and the evaluation of rules and recomendations to practice PA were analyzed in one hundred patients. Results: It was observed commitment on different dimensions of QL, higher values to sexual function and social support (88,6) and lower ones to professional paper (25,2) and physical function (47,7). Most patients shows low values of PAL and most PPA implement the exercises incorrectly. It was observed differences between PAL and some areas of QL. Conclusion: Patients with CKD undergone hemodialysis presented low values to PAL, commitment on QL, and most of the patients that realized PA did not implement rules and recomendations on their own practice.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)