A Fé documentada: perspectivas metodológicas de organização da informação fotográfica sobre romarias de Juazeiro do Norte – Ceará

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação in vitro da resistência estrutural em dentes fragilizados utilizando reforços intra-radiculares

Pós-graduação em Odontologia Restauradora - ICT

Matrizes híbridas siloxano-poliéter incorporadas com argila montmorilonita para liberação controlada de fármaco

Pós-graduação em Química - IQ

Análise da espermatogênese e do cariótipo da espécie Eptesicus furinalis (d’Orbigny, 1847) Vespertilionidae, Chiroptera

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Morphological and biochemical alterations activated by antitumor clerodane diterpenes

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Screening and determination of sulphonamide residues in bovine milk samples using a flow injection system

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Bonding of facial silicon with nanoparticles to an acrylic resin substrate

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mechanisms of SnO2 Nanoparticles Formation and Growth in Acid Ethanol Solution Derived from SAXS and Combined Raman-XAS Time-Resolved Studies

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Structural characterization of an etheno-2 '-deoxyguanosine adduct modified by tetrahydrofuran

The reaction of 2'-deoxyguanosine with the alpha,beta-unsaturated aldehydes trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-nonadienal, and trans,trans-2,4-decadienal in THF gives rise to three novel adducts: 3-(2'-deoxy-beta-D-erythro-pentafuranosyl)-7-[3-hydroxy-1-(3(2'-deoxy-beta-D-erythro-pentafuranosyl)-3,5-dihydro-imidazo[1,2-alpha]purin-9-one-7-yl)-propyl] -3,5-dihydro-imidazo[1,2-alpha]purin-9-one (M) and 3-(2'-deoxy-beta-D-erythro-pentafuranosyl)-7-(tetrahydrofuran-2-yl)-3,5-dihydro-imidazo[1,2-alpha]purin-9-one (A8 and A9), which are not observed in the absence of THF. These adducts were isolated from in vitro reactions by reversed-phase HPLC and fully characterized on the basis of spectroscopic measurements. Adduct A7 consists of two 1,N-2-etheno-2'-deoxyguanosine (1,N-2-epsilondGuo) residues linked to a hydroxy-carbon side chain; adducts A8 and A9 are interconvertible 1,N-2-epsilondGuo derivatives bearing a THF moiety. The proposed reaction mechanism involves the electrophilic attack on 1,N-2-epsilondGuo by the carbonyl of 4-hydroxy-butanal, generated via ring opening of alpha-hydroxy-THF (THF-OH), yielding adducts A8 and A9. A further combination of these adducts with another 1,N-2-epsilondGuo produces the double adduct A7. These findings demonstrate that reactions of unsaturated aldehydes in the presence of THF produce novel condensation 1,N-2-epsilondGuo-THF adducts. Further studies would indicate the relevance of these adducts in THF toxicity.

A Multiple-Vortex Tornado in Southeastern Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efficient one-pot synthesis of 14-aryl-14H-dibenzo [a,j]xanthene derivatives promoted by niobium pentachloride

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O eterno feminino: arquétipos literários em Mujeres de Eduardo Galeano

Le champ littéraire est plein d’oeuvres qui remettent à des mythes. L’ensemble de récits Mujeres, de Eduardo Galeano, a comme thématique la femme et il est composé par des micro-contes, genre narratif qui promeut une condensation maximale d’eléments thématiques et structuraux. Il s’agit des descriptions littéraires où la synthèse est placée ou même niveau que le lyrisme. Ayant pour objectif d’analiser la nature archétypique des mythes sur la féminité, nous avons travaillé spécifiquement les contes de Mujeres où se reconstruisent poétiquement des mythes de la féminité. Méthodologiquement, notre notre étude a pour base la mythocritique et la théorie des structures anthropologiques de l’imaginaire ídéalisées par Gilbert Durand. En partant de ces bases, nous avons réalisé l’analyse des récits qui s’articulent en notre corpus, ayant pour but, celui d’identifier les divers artifices narratifs spécifiques qui y opèrent. Par le moyen des mythèmes présents dans les récits, nous avons révélé les structures archétypiques du texte et nous avons constaté comment elles s’édifient littérairement. En outre, nous avons élucidé la teneur de la représentativité archétypique de la feminité inhérente aux récits et finalement, nous avons rassemblé les situations et les combinatoires qui existent dans l’ensemble de microrécits, traçant les connexions possibles qui y existent. Ainsi, nous avons fait une étude proprement dite, d´analyse mythocritique

Uma revisão sobre a resina uréia-formadeído (RUF) empregada na produção de painéis de madeira reconstituída

According to ABIPA (2009), Brazil is currently among the major producers of reconstituted wood panels, with one of the main factors for this condition, its climate and its large land area, which allows the cultivation of forests, which provide raw materials for these industries. To establish that market as power, Brazil has invested about R$ 1.3 billion in the last 10 years, yet designed an investment of 0.8 billion dollars over the next three years (BNDES, 2008). With the new investments in this segment, we expect a growth of about 66% in the resin consumption of urea-formaldehyde (GPC, 2009) which should also result in major investments by the companies producing this polymer. Currently employees are mainly three types of resins in the production industry panels, as follows: Urea-Formaldehyde Resin (R-UF), melamine-formaldehyde resin (R-MF) and Phenol-Formaldehyde Resin (R-FF). Especially the cost factor, the urea-formaldehyde resin is the most used by companies producing reconstituted wood panels. The UF-R is a polymer obtained by condensation of urea and formaldehyde reactors (usually batch type), characterized by being a thermosetting polymer which makes it very efficient for bonding wood composites. The urea-formaldehyde polymer, to present a quite complex, it becomes very difficult to predict the exact chain resulting in the process of condensation of urea with formaldehyde, so that a greater knowledge of its characteristics and methods for their characterization can result in greater control in industrial processes and subsequent decrease cost and improve the quality of reconstituted wood panels produced in Brazil

Principais marcadores utilizados na avaliação da qualidade do sêmen de animais domésticos

Methods of semen cryopreservation allow changes in spermatic cells, such as damage in plasma and acrossomal membrane and modifications in mitochondrial function due to a disorder in the lipidic bilayer. For effective oocyte fertilization, spermatozoa require functional competent membranes, and intact organelles, acrosome and DNA. However, most laboratory methods used to evaluate semen quality are not highly correlated with fertilizing capacity. The discovery of a variety of fluorochromes and compounds conjugated to fluorescent probes has enabled an accurate assessment of the viability, integrity and function of spermatozoa. Among the most used probes that label the various compartments of the sperm cell there are the membrane impermeable fluorescent dyes to test the membrane integrity, as well as acylated dyes that pass the intact membrane. For the acrossomal integrity the most commonly used method is lectins labeled by a fluorescent probe. The acrosome reaction and spermatic capacitation is detected by the evaluation of membrane architecture and disorder of lipids in plasma membrane. Mitochondrial function can be determined using markers for their aerobic activity. The DNA status of spermatozoa has been determined using the metachromatic properties of Acridine Orange, and the DNA fragmentation can also be assessed by TUNEL assay. Finally, DNA condensation is analyzed using a single cell DNA gel electrophoresis assay that indicates DNA compactation. This monograph aims to compile the various tests used to detect damaged spermatozoa under cryopreservation methods, searching for improve the predictive value of semen analysis with the intention of a successful conception