Estudo da eficácia e citotoxicidade de filme e sistema emulsionado contendo ácido cafeico

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Desoxinivalenol em farinha de trigo: otimização de método analítico, validação e ocorrência

Pós-graduação em Alimentos e Nutrição - FCFAR

Fabrication and characterization of ferrocenece containing hydrogel for glucose biosensor application

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Optimisation of a sample preparation method for the determination of fumonisin B-1 in rice

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Voltammetric sensor for simultaneous determination of p-phenylenediamine and resorcinol in permanent hair dyeing and tap water by composite carbon nanotubes/chitosan modified electrode

p-Phenylenediamine (PPD) and resorcinol (RSN) are hair dye precursors of permanent dyeing more used worldwide. The present work describes a simple and economic voltammetric sensor for simultaneous determination of both components in commercial hair dyeing and tap water at low concentrations. PPD and RSN are oxidized at + 0.17 and + 0.61 V vs. Ag/AgCl at glassy carbon electrode coated by composites of multiwall carbon nanotubes with chitosan (MWNTs-CHT/GCE), which anodic currents density normalized are 10% and 70% higher in relation to the unmodified electrode, respectively. The calibration curve for simultaneous determination of PPD and RSN showed linearity between 0.55 and 21.2 mg L-1 with detection limits of 0.79 and 0.58 mg L-1 to PPD and RSN, respectively. The relative standard deviations found for ten determinations were of 0.73 and 2.35% to 2.70 mg L-1, and 0.87 and 1.08% to 15.96 mg L-1 to PPD and RSN, respectively. The voltammetric sensor was applied to determination of PPD and RSN in tap water and commercial hair dyeing samples and the average recovery for these samples was around 97%. The products generated from PPD and RSN reaction such as was p-quinonediimine and bandrowski base were detected by LC-MS/MS and UV-vis spectrophotometry. (C) 2014 Published by Elsevier B.V.

Flavonoid Detection in Hydroethanolic Extract of Pouteria torta (Sapotaceae) Leaves by HPLC-DAD and the Determination of Its Mutagenic Activity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Scaling properties and universality in a ratchet system

Critical exponents that describe a transition from unlimited to limited diffusion for a ratchet system are obtained analytically and numerically. The system is described by a two dimensional nonlinear mapping with three relevant control parameters. Two of them control the non-linearity while the third one controls the intensity of the dissipation. Chaotic attractors appear in the phase space due to the dissipation and considering large non-linearity are characterised by the use of Lyapunov exponents. The critical exponents are used to overlap different curves of average momentum (dynamical variable) onto a single plot confirming a scale invariance. The formalism used is general and the procedure can be extended to different systems.

A Modified Branch and Bound Algorithm to Solve the Transmission Expansion Planning Problem

In this paper a novel Branch and Bound (B&B) algorithm to solve the transmission expansion planning which is a non-convex mixed integer nonlinear programming problem (MINLP) is presented. Based on defining the options of the separating variables and makes a search in breadth, we call this algorithm a B&BML algorithm. The proposed algorithm is implemented in AMPL and an open source Ipopt solver is used to solve the nonlinear programming (NLP) problems of all candidates in the B&B tree. Strategies have been developed to address the problem of non-linearity and non-convexity of the search region. The proposed algorithm is applied to the problem of long-term transmission expansion planning modeled as an MINLP problem. The proposed algorithm has carried out on five commonly used test systems such as Garver 6-Bus, IEEE 24-Bus, 46-Bus South Brazilian test systems, Bolivian 57-Bus, and Colombian 93-Bus. Results show that the proposed methodology not only can find the best known solution but it also yields a large reduction between 24% to 77.6% in the number of NLP problems regarding to the size of the systems.

Caracterização gfeológico-geotécnica aplicada a gestão de risco no gasoduto GASBOL, trecho Ipeúna/SP - Itirapina/SP

The pipelines are characterized by the great length and linearity, these enterprises are usually associated with the horizon of soil and decomposed rock and accidents in this system usually have high complexity. So this work proposes a study of geological and geotechnical characterization of approximately 40 km ² and a study of risk analysis along 18.3 km of gas pipeline GASBOL, in the municipalities of Ipeúna-SP and Itirapina-SP, in scale 1:25.000, besides correlation between studies. The method for geological and geotechnical characterization is based on physiographic integrated analysis technique, which is supported by literature research, observation and interpretation of satellite imagery (photointerpretation), correlation of products numerical model of ground, fieldwork. The method adopted for risk classification is based on preliminary analysis of hazards (APP) technique, which is identified the geological process, this feature is classified as the susceptibility of occurrence, and then classified as the possible consequence of the process, if this evolves. As a product of the research, we designed a map in 1:25,000 scale, containing a table of geological and geotechnical characteristics of the mapped drives, as well as sectorization risk in each section of the pipeline. Were mapped geological and geotechnical seven units in the study area, delimited in excerpts of which five are classified as high risk, totaling 1.1 km in length of 18.3 km total

Crises de fronteira e estruturas complexas no espaço de parâmetros em um mapeamento dissipativo bidimensional

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Economia solidária e tecnologias sociais: mediação para a emancipação social de grupos autogestionários

The goal of this paper is to critically analyze the practices developed by Solidarity Economy and to merge them with social technologies, aiming to achieve social transformation of popular groups. This transformation consists in the empowerment of those groups in means of work organization, considering their self-management and also the development of techniques and technologies utilized. Based on the understanding that technical development has no neutral character and it follows linearity within society, a discussion around the forms and uses of technology is conducted here, aiming at the perspective of changes in technologies’ development and also assigning social character to them. To think of social technology requires us to consider the space in which it is inserted, once it refers to a collective demand that belongs to self-managed groups. Therefore, to intent beyond self-management work, new productive forces are discussed here, and also the analysis and adhesion of an alternative technology for popular cooperatives

Controle de qualidade e levantamento radiométrico em aparelho de Raios-X médico convencional

Along with the advance of technology, in terms of the expansion of medical exams that uses the ionizing radiation for diagnosis, there is also the concern about quality control for maintaining quality in radiographic imaging and for delivering low dose to the patient. Based on the Federal Order 453 of the Secretariat of Health Surveillance, which takes account of the practical and justification of individual medical exposures, the optimization of radiological protection, limitation of individual dose, and the prevention of accidents, were done through this paper radiodiagnostic tests on medical equipment in order to accept it or not, according to SVS-453. Along with the help and support of P&R Consulting and Medical Physics Marilia, SP, were made Quality Control and Radiometric Control in equipment from various cities across the state of São Paulo. The equipment discussed in this work is classified as conventional X-ray. According to the Federal Order SVS-453, the quality control in the program of quality assurance should include the following minimum set of constancy tests, with following minimum frequency: biennial tests for representative values of dose given to the patients of radiography and CT performed in the service; annual tests for accuracy of the indicator tube voltage (kVp), accuracy of exposure time, half-value layer, aligning the central axis of the beam of x-ray tube, performance (mGy / mA.min.m²), linearity of the rate of kerma on air with the mAs, reproducibility of the kerma on air rates, reproducibility of the automatic exposure, focal spot size, integrity of accessories and clothing for individual protection; semiannually for collimation system accuracy; weekly for temperature processing system and sensitometry processing system. For the room Radiometric Survey it was done a sketch...(Complete abstract click electronic access below)

Influência do porta-enxerto, da configuração de extração e do período de maturação no teor de limonina e na aceitação sensorial do suco de laranja Pêra-Rio

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Determination of anticonvulsants in human plasma using SPME in a heated interface coupled online to liquid chromatography (SPME-LC)

A simple and sensitive method using solid phase microextraction (SPME) and liquid chromatography (LC) with heated online desorption (SPME-LC) was developed and validated to analyze anticonvulsants (AEDs) in human plasma samples. A heated lab-made interface chamber was used in the desorption procedure, which allowed the transference of the whole extracted sample. The SPME conditions were optimized by applying an experimental design. Important factors are discussed such as fiber coating types, pH, extraction time and desorption conditions. The drugs were analyzed by LC, using a C18 column (150 mm 4.6 mm 5 mm); and 50 mmol L1 , pH ¼ 5.50 ammonium acetate buffer : acetonitrile : methanol (55 : 22 : 23 v/v) as the mobile phase with a flow rate of 0.8 mL min1 . The suggested method presented precision (intra-assay and inter-assay), linearity and limit of quantification (LOQ) all adequate for the therapeutic drug monitoring (TDM) of AEDs in plasma.

Quantification of Flavonoids, Naphthopyranones and Xanthones in Eriocaulaceae Species by LC-PDA

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)