Associação da raspagem com antibioticoterapia em um caso de periodontite agressiva generalizada

The treatment of aggressive periodontitis is a challenge to the clinician, therefore the search for effective treatment protocols of this disease is important. The aim of this case report was demonstrate the effectiveness of the combination of systemic antibiotics with non-surgical periodontal therapy in the treatment of generalized aggressive periodontitis. a 27-year-old patient (RCS), smoker for 11 years (10 cigarettes/day on average), with no systemic alteration, attended the periodontal clinic with a complaint abnormal dental position. After the clinical examination, the diagnosis of generalized aggressive periodontitis was defined. The non-surgical periodontal treatment was executed associated with administration of amoxicillin plus metronidazole for ten days. Clinical parameters (Clinical Attachment level, marginal gingival level, periodontal probing depth, bleeding on probing, plaque index and gingival index) and radiographic parameters (distance between the cemento-enamel junction and the bone crest) were evaluated before and after non-surgical periodontal treatment, after antibiotic therapy and three, six and 12 months after the treatment. After one year follow-up, the results showed improvement in clinical and radiographic parameters with stabilized and decreased tooth mobility and absence of tooth loss. It was concluded that the association of non-surgical periodontal therapy with the administration of amoxicillin/metronidazole was effective in the treatment of generalized aggressive periodontitis.

Detecção de Periodontopatógenos, Glicoproteína Emmprin (Cd-147) e sua correlação com MMP-2 e MMP-9

Periodontitis is an infectious disease characterized by the secretion of a variety of inflammatory mediators that lead to destruction of tooth supporting tissues, including the possible loss of alveolar bone, in association with infection with multiple species of bacteria. It is estimated that more than 400 species colonize the biofilm and some oral species related to periodontal disease is present in the subgingival including P. gingivalis, T. forsythia and T. denticola. However, other organisms may be related of this disease, as Filifactor allocis and Prevotella tannerae. These microorganisms and subproducts such as endotoxins released into the extracellular lead to the stimulation of metalloproteinase inducer glycoprotein (EMMPRIN, CD-147), which stimulates the release of MMPs by host cells, like fibroblasts and endothelial cells, thus leading to tissue destruction. The objective of this study was to detect F. allocis, P. tannerae, T. denticola and the glycoprotein EMMPRIN (CD-147) and its correlation with MMP-2 and MMP-9 in subgingival fluid samples of patients with chronic periodontitis. Fluids were collected from healthy and disease subgingival sites of 20 healthy individuals before basic periodontal treatment and after of 60 days of treatment. Their DNAs were extracted and portions of the 16S gene were amplified and performed conventional PCR. For immunological analysis and quantification of EMMPRIN (CD-147), MMP-2 and MMP-9 was used ELISA-Sandwich. Results demonstrated that the disease group showed significantly high amounts of T. denticola, F. alocis and P. tannerae when compared with health sites. MMP-2 and MMP-9 were detected in high concentrations with statistically significantly reduction after periodontal treatment to MMP-2, but without correlation with EMMPRIN.

Achados clínicos, genéticos e microbiológicos de uma família com periodontite agressiva de Maceió

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Matriz oclusal para restauração com resina composta de baixa contração: simplificação eficiência

The composite resin is the material of election for direct restorations in posterior teeth currently. The restorative dentistry aims to improve each day the material and facilitate the restorative technique. This paper describes the technique of occlusal matrix made to speed up and preservation the occlusal surface of a first molar tooth affected by caries lesion. A new resin-based composite was used called Silorane, which may be placed in larger increments due the material has low shrinkage and polymerization stress. The use of occlusal matrix associated with a low shrinkage resin composite can simplify the clinical work, and result in a restoration with excellent reproduction of anatomical.

Matriz Bertholdo/Ricci/Barrotte (BRB): uma simplificação de técnica para obtenção de guia de estratificação com compósitos

Advanced Layering composite resins can be facilitated by a technique called "Lingual Matrix", where a guide is made of elastomer by molding a previously waxed tooth or sculped in an intraoral test drive restoration. This technique has many advantages to sophisticated layering, facilitation stratification, anatomic construcrion and the stages of finishing and polishing. However, in some clinical situations, the unfolding of the steps to obtains this matrix can be time consuming or even infeasible. To facilitate the achievement of this apparatus, a technique was idealized allowing significant reducrion in clinical time. This matrix, called the "BRB Matrix" is widly discussed in a didactic and clinical manner in this article, presenting its advantages in clinical cases where it is imperative to use a guide for conduction a controlled layering. The simplicity of this approach, as well as reduced clinical time and finacial costs turn it feasible in an everyday clinical practice.

Entre a matriz portuguesa e a literatura nacional: a concepção de texto literário para João Ribeiro

This paper aims at rescuing some critical appraisals found in the high school anthology Autores Contemporâneos (1931), by the critic, philologist and writer João Ribeiro, one of the main Brazilian intellectual representatives of the first decades of the twentieth century. João Ribeiro, along with Coelho Neto and, Laudelino Freire, among others, took part in of the panel which compiled, in 1921, the Dicionário da Academia Brasileira de Letras. Therefore, we find the analytical process João Ribeiro, their theoretical observations, concepts and dilemmas which are appointed by him in literary history and criticism of the early twentieth century.

Os efeitos da matriz bioparental nos processos de adoção de crianças e adolescentes

This paper is the result of a homonymous scientific research, funded by CNPq-PIBIC where we understand the adoption process as a process of dissidence in relation to the bio-parental matrix. Founded on a heteronormative naturalization of human sexuality - which presupposes a continuum and naturalized organization among sex / gender / desire – this bioparental matrix sets the binary relation of distinction between the legitimate/illegitimate child as their origin or not arising from “blood ties”. Considering our experience in the Project developed at the Department of Clinical Psychology at UNESP, Assis, SP called “Ties of love: Adoption, Gender, Citizenship and Rights”, we prepared a content analysis - as proposed by Bardin (1977) -, of transcripts of psychological sessions that were made from 2005 to 2012 in the "Center for Research and Applied Psychology “Dra. Betti Katzenstein. Our general objective was to analyze the effects of the bioparental matrix and its impact on children/adolescents and their families as well as estimate the possibilities of escape to the subjection to this bioparental matrix. The results showed us several aspects that may be significant for understanding the discursive crossings related to the practice of adoption. It was observed that there is still a great ambivalence pervading this theme, revealing that there is a discrepancy between what we say and what we do in relation to practices of caring among the adopted children. On the one hand, it was noticed that relatives rationally seek to enhance the bonding of the “emotional ties”, but their practices and beliefs, are still supported in modes of subjectivation that prioritize the biological discourse. This fact reveals a strained and conflictive field that probably weaknesses those families seeking to prioritize the ties of affection. However, as can be seen in this study, it is comforting and motivating to realize the power of resistance of individuals to absolute truths that govern their ways of feeling, affiliating and/ or exert their parenting.

Análise do método suvrel na expressão diferencial a partir da matriz de contagens gerada com dados de RNA-SEQ

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeitos da Exenatida e da Sitagliptina durante a indução da periodontite em ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Polimorfismo do colágeno tipo 3 e da metaloproteinase 9 como fator de risco para a incontinência em muheres com diabete mellitus gestacional

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Presença de candida e de anticorpos anti-candida na cavidade bucal de pacientes com periodontite crônica do adulto

The presence of Candida and the production of histolytic enzyms by the isolated samples were observed in the saliva and gingival fluid in adult chronic periodontitis patients and health ones. It was also verified the quantity of antibodies against Candida (IgG, IgA, IgM and IgE) in the saliva and sera of the same patients through ELISA technique. Yeasts of the genus Candida mainly C. albicans were isolated from saliva in higher number from adult chronic periodontitis patients in relation to the controle with statistically significant difference. The meon of the quantity of isolated Candida (UFC/ml) were higher for periodontítis patients, although this difference was not statistically significative. Samples of Candida isolated from both groups produced hystolytic enzymes (hyaluronidase, condroitin sulfatase, proteinase, phospholipase) that are considered patogenicity factors in periodontol diseases. Only one sample of each group (C albicans) didn't produce the four analysed enzymes. The antibodies levels against Candida (IgG, IgM and IgA in saliva, IgG and IgA in sera and IgG and IgM in gingival Fluid), were statistically higher in adult chronic periodontitis patients in relation to periodontically health individuals, suggesting humoral immune response by periodontitis patients to the yeasts of the genus Candida

Claritromicina como adjuvante ao debridamento periodontal no tratamento de periodontite agressiva generalizada: estudo controlado randomizado

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeito de diferentes terapias locais para o tratamento de periodontite crônica em indivíduos diabéticos tipo 2: estudo clínico controlado randomizado triplo cego de boca dividida com acompanhamento de seis meses

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)