Aspectos clínicos e cirúrgicos do osteossarcoma canino

Osteosarcoma is the primary osseous neoplasia frequently diagnosed in dogs and it’s the main answerable for more than 85% of the neoplasias origened from the skeleton. The average age of onset of the lesion is 7 years, especially in large breeds and giant, with males being more affected than females. In general, 75% of osteosarcomas develop in the appendicular skeleton and 25% in the axial. The forelimbs are more affected than the hindlimbs, since support 60% of body weight. The osteosarcoma diagnosis is made by the analys of the animal’s clinic historic, detailed physique exams, blood exams alkaline phosphatase, xray exams, cytology, biopsy. The treatment of choice is the amputation associated to the chemotherapy. However, in some cases the member is preserved by the allograft technic. The chemotherapy associated to the surgery reduces the total load of the tumor, lengthens the interval of the life and improves the quality of pacient’s life. The most used medicines are cisplatin and doxorubicin. They can be used in separated or associated ways. The prognostic of dogs with osteosarcoma is reserved

Diferenciação osteogênica de células mesenquimais do cordão umbilical canino

Pós-graduação em Ciência Animal - FMVA

Expressão gênica de MMP-2 e 9, TIMP-1 e 2, ATM, TP53, VEGF, COX-2 e CDH-1 no TVT canino

Pós-graduação em Medicina Veterinária - FCAV

Expressão dos genes MDR-1, TP53, BCL-2 e BAX em tumor venéreo transmissível canino e sua relação com a agressividade e resposta à terapia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estabilidade do fator de von Willebrand e fator VIII no crioprecipitado canino em diferentes protocolos de armazenamento

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Otimização do tracionamento de canino impactado pela técnica do arco segmentado: relato de caso clinico

Upper canines impaction are considered the second most frequent and are associated to important esthetics and functional limitations. Among the treatment strategies described in the literature the most commonly used are the extraction of the primary canines and the surgical exposure followed by orthodontic traction, that requires an adequate interdisciplinary approach. The aim of this case report is to draw the attention of the clinician to the possibility of adapting the segmented arch technique to manage a canine impaction clinical case.

Tratamento cirúrgico de canino incluso em mento: relato de caso

The mandibular and maxillary canines when well positioned in the arch, are important functionally and aesthetically. Although these teeth are frequently malpositioned in the dental arch, their absence of eruption are not common, occuring more frequently with the maxillary canine than the mandibular canine. The canine transmigration is a well-known pre eruptive phenomenon in which the tooth goes thru the facial midline, occurring more frequently in the mandible than in maxila. Females are more susceptible than males and the right side more than the left one. Normally the patients do not show any symptoms, and this condition is observed during radiographic exams to diagnose the late exfoliation of the deciduous canine or for any other purpose. Due to the relationship between impacted canines and pathologic lesions, infection, trauma to the adjacent teeth, pain, ectopic eruption and interference with prosthesis, it´s indicated the surgical extraction of these teeth. The goal of this article is to describe and discuss the surgical treatment of an impacted canine (43) in the chin.

Tumor mamário canino: estudo in vitro, imunomarcação e ação da doxorrubicina

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Control Methods and Evaluation of Bacterial Growth on Fresh and Cooled Stallion Semen

The penis and prepuce of the stallion have a high bacterial load on its surface, forming a natural microbial flora that contaminates the semen during ejaculation. Bacterial growth in semen may cause a decline on sperm quality, viability, and fertility and predisposes the occurrence of endometritis in inseminated mares. Thus, the aim of this study was to evaluate the effect of penile wash before semen collection, the addition of different commercial skim milk-based extenders containing antibiotics (BotuSemen and INRA96), and the removal of seminal plasma by filtration on the quality, viability, and bacterial proliferation on fresh and cooled stallion semen. Animals that were never submitted to penile wash before semen collection tended to have lower bacterial contamination in the ejaculate. Semen samples extended in BotuSemen showed superiority in total motility, progressive motility, average path velocity, and rapid sperm and lower bacterial contamination in relation to semen samples extended in INRA96 after 24 hours of cooling. No difference was found in these parameters between the storage temperatures (5 degrees C and 15 degrees C). Furthermore, the removal of seminal plasma by filtration reduced the bacterial load in semen after cooling. In conclusion, the penile wash before semen collection tended to reduce the bacterial growth in fresh semen. The use of a semen extender with appropriate antibiotics and removal of seminal plasma by filtration were effective in reducing the bacterial contamination and preserved the quality of cooled stallion semen. (C) 2015 Elsevier Inc. All rights reserved.

Fixed-time insemination with frozen semen in mares: is it suitable for poorly fertile stallions?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Spermatozoon ultrastructure and semen parameters of Brycon vermelha (Characiformes, Characidae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Semen characteristics and refrigeration in free-ranging giant anteaters (Myrmecophaga tridactyla)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Vacina de DNA: uma alternativa para o tratamento do melanoma canino: revisão de literatura

O melanoma é considerado um dos tumores cutâneos de maior importância em cães devido ao seu caráter agressivo, à capacidade de produzir metástases em estágios precoces e à baixa resposta aos tratamentos não cirúrgicos. Recentemente, as vacinas de DNA apresentam-se promissoras na terapêutica do melanoma canino. O objetivo deste trabalho é apresentar uma revisão bibliográfica sobre o assunto. As vacinas de DNA são baseadas em plasmídeos que contêm o gene codificante para o antígeno alvo, expressando-o na célula do hospedeiro e apresentando, assim, vantagens em relação às vacinas tradicionais, como: facilidade de produção, estabilidade térmica, baixo custo e estimulação da resposta imune celular (linfócitos T CD8+). Devido ao sucesso limitado das terapias padrões, o estabelecimento de uma vacina de DNA efetiva aumenta a possibilidade de uma terapia promissora para o melanoma canino, podendo trazer novas expectativas aos animais portadores dessa neoplasia.

Elastografia acoustic radiation force impulse (ARFI), doppler e ultrassonografia contrastada do baço canino

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Perfil fenotípico de potenciais células iniciadoras tumorais no tumor venéreo transmissível canino ex vivo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)