34 resultados para Integral readings

em Deakin Research Online - Australia


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This paper describes teachers as bricoleurs who are professionals engaging in rigorous theoretical work as they construct meaningful assemblages of classroom practice. The author uses examples of two teachers taking up critical literacy discourses in their teaching and conversations to explain the construction of the teacher as bricoleur. Drawing on work by Deleuze and Guattari, a rhizotextual analysis of data is undertaken to explain the connections between the disparate discourses used by the two teachers and the documents of the Queensland English Syllabus. This understanding of the professional work of teachers negates assumptions about teachers as atheoretical and blind followers of departmental policies and curriculum directives. The author concludes with a description of one method for giving teachers the time and reflexive space to theoretically engage with issues surrounding their professional practice.

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Protein kinase C (PKC) is a family of serine/threonine protein kinases that are pivotal in cellular regulation. Since its discovery in 1977, PKCs have been known as cytosolic and peripheral membrane proteins. However, there are reports that PKC can insert into phospholipids vesicles in vitro. Given the intimate relationship between the plasma membrane and the activation of PKC, it is important to determine whether such “membrane-inserted” form of PKC exists in mammalian cells or tissues. Here, we report the identification of an integral plasma membrane pool for all the 10 PKC isozymes in vivo by their ability to partition into the detergent-rich phase in Triton X-114 phase partitioning, and by their resistance to extractions with 0.2 M sodium carbonate (pH 11.5), 2 M urea and 2 M sodium chloride. The endogenous integral membrane pool of PKC in mouse fibroblasts is found to be acutely regulated by phorbol ester or diacylglycerol, suggesting that this pool of PKC may participate in cellular processes known to be regulated by PKC. At least for PKCα, the C2–V3 region at the regulatory domain of the kinase is responsible for membrane integration. Further exploration of the function of this novel integral plasma membrane pool of PKC will not only shed new light on molecular mechanisms underlying its cellular functions but also provide new strategies for pharmaceutical modulation of this important group of kinases.

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Offers a collection of new topical and contemporary readings in audit. With many subjects on audit and assurance offering a practical industry perspective to the audit process, this volume presents a range of audit topics that will contextualise the audit discipline and introduce a range of professional issues.

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This paper studies the integral terminal sliding mode cooperative control of multi-robot networks. Here, we first propose an integral terminal sliding mode surface for a class of first order systems. Then, we prove that finite time consensus tracking of multi-robot networks can be achieved on this integral terminal sliding mode surface. Simulation results are presented to validate the analysis.

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In the present work, the carbon diffusion in steel, where the carbon diffusivity varies with the carbon content, was solved with the integral methods under the third boundary condition. The variation of carbon diffusivity in steel with the carbon content was described with two different functions ie. linear dependence and exponential dependence. The integral approximation for both cases was improved with the numerical computation to more accurately predict the carbon profiles. The integral solution is more accurate than the formulation based on the assumption of a constant diffusivity or those based on the assumption of a constant diffusivity and/or constant carbon content at part surface. It is also more easily used in practice than the numerical method to describe the carburising process and predict the carbon content at steel surface and carbon profiles in treated layer.

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