Incredibly close encounters : magical realism and the intimate elegies of Jonathan Safran Foer’s everything is illuminated and extremely loud and incredibly close

This paper will investigate the relationship between prose elegy and magical realism in Jonathan Safran Foer’s novels, Everything is Illuminated and Extremely Loud and Incredibly Close. It will propose that absence is generative, and that the state of melancholia—or unsuccessful, unresolved grief—is conducive to creativity.

Magical realism and experiences of extremity

Examining magical realist texts including Tim O’Brien’s Going After Cacciato (1991), and Jonathan Safran Foer’s Everything is Illuminated (2002) and Extremely Loud and Incredibly Close (2006), this paper discusses how magical realism examines the extremities of trauma and fear, proposing that magical realist narratives afford a unique ability to represent trauma in a way that is not open to the stylistics of literary realism. Blending the real or believable with the fantastically outrageous, magical realist narratives typically destabilise and disorder privileged centres of ‘truth’ and ‘reality’, demonstrating the constructedness of knowledge and history. Accordingly, magical realist strategies are frequently used in interventionist or counter narratives that refuse to adhere to privileged versions of truth or history and insist upon a multiplicity of experience. The majority of magical realist scholarship explores how the genre undermines hegemonic perspectives of history to clear a space for marginal representations of the past. However, as this paper argues, magical realist narratives also provide a unique space for writing about experiences of extremity. Examining the role of fantasy in representations of violence and trauma, this paper proposes that rupturing a realist narrative with the magical or un-real accommodates representations of extremity by conveying the ‘felt’ experience of trauma.

Literature as activism: interrogating the 21st century demise of the Arendtian political public sphere

This article explores Don DeLillo's literary activism through Arendtian perspectives to investigate what the demise of literature's relevance, specifically in a political context, may mean in the current era of an increasingly complex and conflicting 'web of human relationships'.  In that it is accepted that narrative has a particular ability to reveal insights as prelinguistic elements that are distinct from all we are able to access through our limited human perceptions, it remarks the Lacanian paradox that if being is in excess of language, then language is the medium by which this is accessed in the world. For DeLillo, writers may be under threat in a dynamic but destabilizing era, their art superceded by technology and fundamentalist terrorism, however, as suggested in Mao II, this renders the writer all the more necessary.  It is at the point at which the writer has nothing to say or is under duress to say noting, that a human crisis is reached. I ask, do current forms of political pressure to censure literature constitute a further diminishing of the Arendtian political public domain in which speech as action has primacy?

Measurement and data transmission validity of a multi-biosensor system for real-time remote exercise monitoring among cardiac patients

Background: Remote telemonitoring holds great potential to augment management of patients with coronary heart disease (CHD) and atrial fibrillation (AF) by enabling regular physiological monitoring during physical activity. Remote physiological monitoring may improve home and community exercise-based cardiac rehabilitation (exCR) programs and could improve assessment of the impact and management of pharmacological interventions for heart rate control in individuals with AF.

Objective: Our aim was to evaluate the measurement validity and data transmission reliability of a remote telemonitoring system comprising a wireless multi-parameter physiological sensor, custom mobile app, and middleware platform, among individuals in sinus rhythm and AF.

Methods: Participants in sinus rhythm and with AF undertook simulated daily activities, low, moderate, and/or high intensity exercise. Remote monitoring system heart rate and respiratory rate were compared to reference measures (12-lead ECG and indirect calorimeter). Wireless data transmission loss was calculated between the sensor, mobile app, and remote Internet server.

Results: Median heart rate (-0.30 to 1.10 b∙min-1) and respiratory rate (-1.25 to 0.39 br∙min-1) measurement biases were small, yet statistically significant (all P≤.003) due to the large number of observations. Measurement reliability was generally excellent (rho=.87-.97, all P<.001; intraclass correlation coefficient [ICC]=.94-.98, all P<.001; coefficient of variation [CV]=2.24-7.94%), although respiratory rate measurement reliability was poor among AF participants (rho=.43, P<.001; ICC=.55, P<.001; CV=16.61%). Data loss was minimal (<5%) when all system components were active; however, instability of the network hosting the remote data capture server resulted in data loss at the remote Internet server during some trials.

Conclusions: System validity was sufficient for remote monitoring of heart and respiratory rates across a range of exercise intensities. Remote exercise monitoring has potential to augment current exCR and heart rate control management approaches by enabling the provision of individually tailored care to individuals outside traditional clinical environments.

Remotely delivered exercise-based cardiac rehabilitation: design and content development of a novel mHealth platform

BACKGROUND: Participation in traditional center-based cardiac rehabilitation exercise programs (exCR) is limited by accessibility barriers. Mobile health (mHealth) technologies can overcome these barriers while preserving critical attributes of center-based exCR monitoring and coaching, but these opportunities have not yet been capitalized on.

OBJECTIVE: We aimed to design and develop an evidence- and theory-based mHealth platform for remote delivery of exCR to any geographical location.

METHODS: An iterative process was used to design and develop an evidence- and theory-based mHealth platform (REMOTE-CR) that provides real-time remote exercise monitoring and coaching, behavior change education, and social support.

RESULTS: The REMOTE-CR platform comprises a commercially available smartphone and wearable sensor, custom smartphone and Web-based applications (apps), and a custom middleware. The platform allows exCR specialists to monitor patients' exercise and provide individualized coaching in real-time, from almost any location, and provide behavior change education and social support. Intervention content incorporates Social Cognitive Theory, Self-determination Theory, and a taxonomy of behavior change techniques. Exercise components are based on guidelines for clinical exercise prescription.

CONCLUSIONS: The REMOTE-CR platform extends the capabilities of previous telehealth exCR platforms and narrows the gap between existing center- and home-based exCR services. REMOTE-CR can complement center-based exCR by providing an alternative option for patients whose needs are not being met. Remotely monitored exCR may be more cost-effective than establishing additional center-based programs. The effectiveness and acceptability of REMOTE-CR are now being evaluated in a noninferiority randomized controlled trial.

How does ecological disturbance influence genetic diversity?

Environmental disturbance underpins the dynamics and diversity of many of the ecosystems of the world, yet its influence on the patterns and distribution of genetic diversity is poorly appreciated. We argue here that disturbance history may be the major driver that shapes patterns of genetic diversity in many natural populations. We outline how disturbance influences genetic diversity through changes in both selective processes and demographically driven, selectively neutral processes. Our review highlights the opportunities and challenges presented by genetic approaches, such as landscape genomics, for better understanding and predicting the demographic and evolutionary responses of natural populations to disturbance. Developing this understanding is now critical because disturbance regimes are changing rapidly in a human-modified world.

Globalisation, the environment and recent trends in international trade

The process of globalization has had far-reaching social as well as economic effects. The term "globalization" is generally taken to mean an increase in international transactions in markets for goods, services and factors of production and a growth in institutions .that straddle international borders. This development has also meant that the corporate-governance mechanisms have to be reinforced to ensure fairness and transparency as well as social responsibility. Finally, international infrastructure and institutions have to evolve to facilitate and ameliorate the effects of the growth in this world trade on the environment, sustainable development and bio-diversity. This paper provides an overview of the current developments in all these areas.

Long-term reproductive success of Australasian gannets (Morus serrator)

Life history theory predicts that individuals make trade-offs between investment in current reproduction, future reproductive potential and success in order to maximise lifetime reproductive success (LRS). Factors that may influence LRS in seabirds include delayed maturity, small clutches, high adults survivorship and long life spans. Studies have shown that reproductive success of seabirds increases with age and experience. Australasian gannets are long-lived seabirds that typically commence breeding at five or six years of age. A small colony of gannets was monitored over 12 years. This study aimed to identify patterns of long-term individual breeding biology. Results indicate that nest site, pair bond duration, age and breeding experience are all important factors in reproductive success. Relationships were found between breeding success and several variables including breeding experience, pair bond duration and nest site quality. Identifying and understanding the factors that contribute to individuals’ reproductive success is of critical importance for future conservation and management of seabird species.

Anti-Americanism: recent sources

Anti-American sentiment has, it would seem, increased in the wake of the election of George Bush, jr. and the US’s response to the events of
September 11. Commentators within the US, and globally, have analysed the recent variants of a long-standing condition. Below is a review of recent coverage of the phenomenon. The entries for the print sources are divided into:

(1) analyses of anti-Americanism written in the US,
(2) accounts of international expressions of anti-Americanism.

Plastic crystal behaviour in tetraethylammonium dicyanamide

The plastic crystal tetraethylammonium dicyanamide ([N_2,2,2,2][dca]) has been investigated with an emphasis on structure and dynamics in the plastic phase. It was found that almost all of the volume expansion occurs at the II → I transition, with no volume expansion at the melt transition (as normally observed for crystals). The conductivity of this material shows a rapid increase at temperatures below the II → I transition, reaching values ~ 10^{− 3} S/cm in Phase I, and 0.1 S/cm in the melt. The NMR measurements show that there is a sudden onset of rotational motions of the cations at the plastic transition; below this temperature the cations appear static. The rotational motion of the cation in Phase I has been discussed in terms of isotropic tumbling.

Impacts of currency fluctuations on Japanese foreign direct investment

The Japanese currency has appreciated substantially against most other currencies over the last two decades. During the same time Japan has become one of the world's largest providers of FDI. Japan's share of total FDI outflows increased from about 6 percent during the late 70's to 21 percent in 1990 while its share of the total stock of FDI in the world increased from less than 1 percent in 1960 to more than 13 percent in 1993. Not surprisingly, Japan's role in international business in general and its FDI activities, in particular, have attracted considerable attention from researchers world wide. However, much of this attention has been directed towards the patterns and determinants of Japanese foreign direct investment, in particular to the United States. The impact of changes in the value of the Yen on Japanese FDI has been largely overlooked. Thus, this paper fills an important gap in the literature by focusing on the influence of changes of the exchange rate on Japanese foreign direct investment. A comprehensive simultaneous equa-tion model of Japanese FDI is developed on a regional level to gauge the extent to which currency fluctuations affect Japanese FDI activities. The results suggest that the exchange rate is an effective mechanism through which to influence FDI. Thus, the exchange rate should not be overlooked by the World Trade Organisation in its efforts to further liberalise investment through the Multilateral Agreement on Investment.

Pasture height and crop direction influence reptile movement in an agricultural matrix

Tackling the global threat of habitat fragmentation on biodiversity requires knowledge of how species move within agricultural landscapes. However, the specific mechanisms influencing dispersal within such landscapes remain poorly understood. The objective of our study was to assess how matrix type (improved pasture, native pasture or crop) and structure (grass height) influence fine-scale reptile movement, as well as influences of crop sowing direction and setting-sun position. In an agricultural region of south-eastern Australia, we first released 20 individuals of an arboreal gecko (Christinus marmoratus) at set distances from trees to determine the distance at which they could perceive their tree habitat (perceptual range). We then translocated 36 individuals into six matrix environments within their perceptual range of isolated trees to examine how gecko movement was modified by the type and structure of the matrix. We also recorded crop sowing direction and setting-sun position and examined all recorded tracks using angular statistics. We found that geckos exhibited a perceptual range of 40–80m. Short matrix environments promoted direct movements towards trees, irrespective of matrix type. Furthermore, movements were significantly affected by crop sowing direction with individuals following the planted lines. Our study has three significant implications: (i) restoring mature tree spacing to 80 m apart will assist gecko movements, (ii) targeted management for low pasture height, such as by maintaining directional narrow strips of low vegetation among taller pastures, might assist movement and facilitate increased connectivity, (iii) directional sowing of crops between habitat patches presents a simple but potentially effective tool for reconnecting fragmented landscapes.

Genome - wide association study identifies novel breast cancer susceptibility loci

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and the residual genetic variance is likely to be due to variants conferring more moderate risks. To identify further susceptibility alleles, we conducted a two-stage genome-wide association study in 4,398 breast cancer cases and 4,316 controls, followed by a third stage in which 30 single nucleotide polymorphisms (SNPs) were tested for confirmation in 21,860 cases and 22,578 controls from 22 studies. We used 227,876 SNPs that were estimated to correlate with 77% of known common SNPs in Europeans at r² > 0.5. SNPs in five novel independent loci exhibited strong and consistent evidence of association with breast cancer (P < 10^-7). Four of these contain plausible causative genes (FGFR2, TNRC9, MAP3K1 and LSP1). At the second stage, 1,792 SNPs were significant at the P < 0.05 level compared with an estimated 1,343 that would be expected by chance, indicating that many additional common susceptibility alleles may be identifiable by this approach.