88 resultados para modern -- 21st century -- Themes
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Book review of Teaching Secondary School Mathematics : Research and Practice for the 21st Century by Merrilyn Goos, Gloria Stillman & Colleen Vale
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This paper argues that a particular form of selfhood has come to dominate the horizons of identity in the Western democracies at this time - I refer to this form of personhood as the entrepreneurial self. The paper argues that the figure (population) of ‘Youth at-risk’, in its negativity, illuminates the positivity that is the entrepreneurial Self. That is, the discourses that construct Youth at-risk reveal the truths about whom we should, as adults, become. The paper engages with Foucault’s theories of government, of (Neo)Liberalism as a problematisation of the practise of Liberal welfare government, and of the ways in which certain psychological discourses articulate with (Neo)Liberal views of enterprise to produce a view of the Self as the entrepreneurial Self.
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The modification of an interface on a molecular level with more than one molecular ‘building block' is essentially an example of the ‘bottom–up' fabrication principle of nanotechnology. The fabrication of such integrated molecular systems in electrochemistry has seen rapid progress in recent years via the development of sensing interfaces fabricated using self-assembled monolayers (SAMs). This review outlines recent advances and applications of self-assembled monolayers for modifying electrodes with an emphasis on the development of integrated molecular systems. First, some basic issues regarding fabricating integrated molecular systems, such as the role of the surface topography of the electrode and patterning surfaces, are discussed. Subsequently an overview of recent developments in pH, inorganic and bio sensing involving the use of SAMs is given. Finally emerging trends in using molecular building blocks in the fabrication of integrated molecular systems, such as nanotubes, dendrimers and nanoparticles, are reviewed.
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For the last decade or so, educational policy makers and researchers in many countries have been calling for significant changes to the way mathematics is taught in secondary schools. Australian mathematics curriculum documents now promote learning goals that go beyond mastery of a pre-determined body of knowledge and procedures - the traditional emphasis on facts, skills, formulae - to include mathematical reasoning and problem solving, communication, and real world applications. There is also pressure to move away from over-reliance on teacher-centred practices such as exposition and individual seatwork, towards activities that promote learners' involvement in constructing, applying, and evaluating mathematical ideas. Further impetus for reform comes from research recommending that if learners are to develop mathematically powerful forms of thinking and habits of mind, then classrooms should immerse them in the authentic practices of the discipline by supporting a culture of collaboration and sense-making. Teaching Secondary School Mathematics - incorporates recent developments in research and practice and applications to teaching mathematics in Australian secondary schools. Covering such areas as curriculum, pedagogy and assessment; teaching mathematical content; equity and diversity in the classroom; and professional and community engagement, it is an invaluable resource for all practising and pre-service mathematics teachers.
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Purpose: The aim was to document contact lens prescribing trends in Australia between 2000 and 2009.
Methods: A survey of contact lens prescribing trends was conducted each year between 2000 and 2009. Australian optometrists were asked to provide information relating to 10 consecutive contact lens fittings between January and March each year.
Results: Over the 10-year survey period, 1,462 practitioners returned survey forms representing a total of 13,721 contact lens fittings. The mean age (± SD) of lens wearers was 33.2 ± 13.6 years and 65 per cent were female. Between 2006 and 2009, rigid lens new fittings decreased from 18 to one per cent. Low water content lenses reduced from 11.5 to 3.2 per cent of soft lens fittings between 2000 and 2008. Between 2005 and 2009, toric lenses and multifocal lenses represented 26 and eight per cent, respectively, of all soft lenses fitted. Daily disposable, one- to two-week replacement and monthly replacement lenses accounted for 11.6, 30.0 and 46.5 per cent of all soft lens fittings over the survey period, respectively. The proportion of new soft fittings and refittings prescribed as extended wear has generally declined throughout the past decade. Multi-purpose lens care solutions dominate the market. Rigid lenses and monthly replacement soft lenses are predominantly worn on a full-time basis, whereas daily disposable soft lenses are mainly worn part-time.
Conclusions: This survey indicates that technological advances, such as the development of new lens materials, manufacturing methods and lens designs, and the availability of various lens replacement options, have had a significant impact on the contact lens market during the first decade of the 21st Century.
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The notion of mathematical literacy advocated by PISA (OECD, 2006) offers a broader conception for assessing mathematical competences and processes with the main focus on the relevant use of mathematics in life. This notion of mathematical literacy is closely connected to the notion of mathematical modelling whereby mathematics is put to solving real world problems. Indonesia has participated as a partner country in PISA since 2000. The PISA trends in mathematics from 2003 to 2009 revealed unsatisfactory mathematical literacy among 15-year-old students from Indonesia who lagged behind the average of OCED countries. In this paper, exemplary cases will be discussed to examine and promote mathematical literacy at teacher education level. Lesson ideas and instruments were adapted from PISA 2006 released items. The potential of such tasks will be discussed based on case studies of implementing these instruments with samples of pre-service teachers in Yogyakarta.
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Most indicators of species and ecological health suggest that our current efforts are inadequate to stem species losses, especially in the face of increasing threats from invasive species and climate change. This has driven a commitment to seek integrated conservation management across many tenures to support our protected areas. To make this happen we need all sectors to break down silos and explore more effective partnerships to achieve conservation at scale, with many different land managers and communities.
This publication illustrates a rich variety of such innovation – new partnerships and models for the establishment, management, financing and governance of both protected areas and initiatives on other lands. Its key purpose is to illustrate that new approaches are possible and workable and to give impetus to these directions. However, the book also illustrates that the path to new approaches will not be without challenges and the occasional blockage. The period of production has seen major changes in government policies, funding cuts, change in personnel and questioning of the business models with some abandonment of the directions within this publication.
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Aptamers, also known as chemical antibodies, are short single-stranded DNA, RNA or peptide molecules. These molecules can fold into complex three-dimensional structures and bind to target molecules with high affinity and specificity. The nucleic acid aptamers are selected from combinatorial libraries by an iterative in vitro selection procedure known as systematic evolution of ligands by exponential enrichment (SELEX). As a new class of therapeutics and drug targeting entities, bivalent and multivalent aptamer-based molecules are emerging as highly attractive alternatives to monoclonal antibodies as targeted therapeutics.
Aptamers have several advantages, offering the possibility of overcoming limitations of antibodies: 1) they can be selected against toxic or non-immunogenic targets; 2) aptamers can be chemically modified by using modified nucleotides to enhance their stability in biological fluids or via incorporating reporter molecules, radioisotopes and functional groups for their detection and immobilization; 3) they have very low immunogenicity; 4) they display high stability at room temperature, in extreme pH, or solvent; 5) once selected, they can be chemically synthesized free from cell- culturederived contaminants, and they can be manufactured at any time, in large amounts, at relatively low cost and reproducibly; 6) they are smaller and thus can diffuse more rapidly into tissues and organs, leading to faster targeting in drug delivery; 7) they have lower molecular weight that can lead to faster body clearance, resulting in a low background noise for imaging and minimizing the radiation dose to the patient in diagnostic imaging. Thus, the high selectivity and sensitivity, ease of screening and production, chemical versatility as well as stability make aptamers a class of highly attractive agents for the development of novel therapeutics, targeted drug delivery vehicles and molecular imaging.
In the review, we will discuss the latest technological advances in developing aptamers, its application as a novel class of drug on its own, as well as in surface functionalization of both polymer nanoparticles or nanoliposomes in the treatment of cancer, viral and autoimmune diseases.