A question of self-preservation : immunopathology in influenza virus infection

Influenza A viruses that circulate normally in the human population cause a debilitating, though generally transient, illness that is sometimes fatal, particularly in the elderly. Severe complications arising from pandemic influenza or the highly pathogenic avian H5N1 viruses are often associated with rapid, massive inflammatory cell infiltration, acute respiratory distress, reactive hemophagocytosis and multiple organ involvement. Histological and pathological indicators strongly suggest a key role for an excessive host response in mediating at least some of this pathology. Here, we review the current literature on how various effector arms of the immune system can act deleteriously to initiate or exacerbate pathological damage in this viral pneumonia. Generally, the same immunological factors mediating tissue damage during the anti-influenza immune response are also critical for efficient elimination of virus, thereby posing a significant challenge in the design of harmless yet effective therapeutic strategies for tackling influenza virus.

Voice art

This study investigated people's ability to control changes in voice volume in order to create digital art. The results demonstrated that with practice, people without previous vocal training are able to improve control over their voice volume. However, it is not sufficient to create art.

There's a fly in my soup : the influence of service guarantees and personal requests on customer voice

Anecdotal evidence suggests that service guarantees and personal requests by service workers encourage customers to voice following failure. However, empirical support for these tactics in facilitating complaints to the organisation is limited. To address this deficiency, a 3 (guarantee treatment: none, unconditional or combined) x 2 (personal request to voice: yes or no) x 2 (failure severity: minor or major) full factorial, between subjects experiment was conducted in a restaurant context. Findings suggest that offering a service guarantee, regardless of whether it is unconditional or combined, can encourage voice. Severity of the failure was also found to be associated with voice. Surprisingly, however, a personal request to voice was not related to customers’ voice intentions. Implications of the findings are discussed.

Giving the people a voice? Experiments with consultative authoritarian institutions in China

In the last decade Chinese consultative authoritarianism has been renewed through many political and administrative innovations and tools. Authoritarian rule in China is now permeated by a wide variety of consultative and deliberative practices. These practices stabilize and strengthen authoritarian rule, leading to deliberative authoritarianism, an advanced form of consultative authoritarianism. This paper discusses two experiments—deliberative polling at Zeguo, Zhejiang, and a township election in Ya'an, Sichuan. Through these two cases we examine the direction which the development of consultative authoritarianism is presently taking, and the potentials and limitations of such input mechanisms in an authoritarian setting.

Managing industrial world heritage sites : preservation, presentation and sustainability

This thesis uses case study methodology to explore how the concept of sustainable development is being applied at industrial World Heritage sites. The thesis proposes a model of sustainable heritage management that is relevant to industrial heritage sites, as well as to other complex heritage sites, including historic urban landscapes.

Mobility, aspiration, voice : a new structure of feeling for student equity in higher education

There is a changed ‘structure of feeling’ emerging in higher education systems, particularly in OECD nations, in response to changed social, cultural and economic arrangements. Taking a student equity perspective, the paper names this change in terms of ‘mobility’, ‘aspiration’ and ‘voice’. It argues that (1) new kinds and degrees of mobility are now a significant factor in sustaining unequal access to and experience of higher education for different student groups, (2) despite government and institutional aspirations to expand higher education, students' desires for university are not a given among new target populations and (3) while universities are seeking to enroll different students in greater numbers, the challenge now is how to give greater voice to this difference. Drawing on these themes of mobility, aspiration and voice and taking recent changes to higher education policy in Australia as the case, the paper presents a new conceptual framework for thinking about student equity in HE. The framework extends from established approaches that focus on barriers to accessing higher education in order to focus on people's capacities in relation to higher education participation.

A right to respond? Monopolisation of 'voice' in CMS

This paper explores the power effects of, and possible justifications for, the differential 'voice' and 'silence' accorded to academic and non-academic subjects within Critical Management Studies (CMS). I explore these issues through a discussion of the practice of 'giving voice' to some subjects critiqued in CMS journal articles by providing them with the opportunity to publish a 'response'. I question the justification for extending this right only to academic subjects, and use this example to provoke CMS to question further its institutional orientation to issues of voice and silence in relation to the non-academic research subject.

Cartoon voice saying no several times SFX

"No, no, no, no, no, no ... no".

Multimodal synthesis and the voice of the multimedia author in a Japanese EFL context

This paper examines a powerful potential of multimodal design: meaning that transcends the total semiotic contribution of a text's constituent parts. With reference to data drawn from the digital storytelling practices of Japanese university students, the author argues and demonstrates that in the current semiotic climate, characterised by the increasing availability and complexity of communication tools and ready appropriation of available designs, practices of multimedia authorship truly can evince expression that is authentically multiplicative. However, this sort of meaning making does not automatically come about. Controlling the inherent polysemy of multimodal texts, in the author's view, is a matter of recognising points of semantic correspondence among co-deployed images, language, etc. and creating syntheses of potential meaning that cut across these semiotic modes. The author further argues that it is in this way that the voice of the multimodal author can most clearly be heard, particularly in cases in which a language learner–author integrates elements within a multimedia text that encode meaning in the L2.

I'm the slice of pie that's ostracised.... : Foucault's technologies, and personal agency, in the voice of women who are homeless, Adelaide, South Australia

In contrast to the international research (particularly in the United Kingdom and North America), much of the Australian literature regarding homelessness to date omits the perspective of people who are homeless. In contributing to the fledgling Australian literature in the field, the following article adopts a secondary approach to the data analysis of original research. When analysed, the voices of homeless women from an agency in Adelaide, South Australia exhibit elements of both Foucault’s technologies of domination and the self. While the results show that the women do have a powerful sense of the broader external issues exerted on them (reflecting both technologies of domination and the self), the analysis also reveals ambiguities in their responses. Apparent in the voice of homeless women is a sense of personal agency which appears to be absent in Foucault’s technologies. By considering the viewpoints of homeless women, various policy implications can also be drawn. Indeed, this is one of the motivations of the article, namely to inject into policy debate and development the voices of the people most adversely affected by it. The policy implications of the women’s voices centre around the desire to be included rather than remain on the margins, the need for supportive relationships, the necessity to take small steps to independent living, and the need for more affordable, independent housing.

Attempting to hear the excluded : the voice of homeless people and policy implications

Until recently, there have been very few systematic attempts to hear what people who are homeless say about their lives and situations. Yet there are a few exceptions particularly in the United States and the United Kingdom (for example, Snow & Anderson 1993; Hutson & Liddard 1994). The Inquiry which resulted in the Burdekin Report in Australia also held consultations in which people who were homeless submitted evidence (Human Rights and Equal Opportunity Commission 1989). Other Inquiries have done likewise and some reports have used the accounts of people who are homeless (for example Bartholomew 1999; Fopp 1989; MacKenzie & Chamberlain 2003).