Biopharmaceutical innovation and industrial developments in South Korea, Singapore and Taiwan

South Korea, Singapore and Taiwan are well known as export-oriented developmental states which for decades employed industrial policy to target particular industries for government support. In the past fifteen years, these three countries all identified the biopharmaceutical industry as a strategic sector. This article explores, through economic analysis, the rationale for this decision and the strategies chosen for linking into the global bio-economy with the objective of catching up in biopharmaceuticals. The paper identifies three comparative advantages enjoyed by these countries in the biopharma sector: (1) public investments in basic research; (2) private investments in phase 1 clinical trials; and (3) a potentially significant contract research industry managing latter-stage clinical trials. Governments employ a range of industrial policies, consistent with these comparative advantages, to promote the biopharmaceutical industry, including public investment in biomedical hubs, research funding and research and development (R&D) tax credits. We argue that the most important feature of the biopharmaceutical industry in these countries is the dominant role of the public sector. That these countries have made progress in innovative capabilities is illustrated by input measures such as R&D expenditure as share of gross domestic product, number of patents granted and clinical trials, and volume of foreign direct investment. In contrast, output indicators such as approval of new chemical entities suggest that the process of catching up has only just commenced. Pharmaceutical innovation is at the stage of mainly generating inputs to integrated processes controlled by the globally incumbent firms.

The relationship between innovation and entrepreneurship : easy definition, hard policy

The paper argues that innovation is the combination of an inventive process and an entrepreneurial process to create new economic value for defined stakeholders and focuses on the policy implications of this duality. Attention is concentrated on summarising the entrepreneurial process and its importance to innovation policy and avoids any detailed elaboration of the invention process. A very brief overview of the invention process is followed by a moderately detailed summary of Hindle's (2008) model of entrepreneurial process. With an understanding and formal articulation of entrepreneurial process it becomes possible to focus on the key issues that ought to inform the development of innovation policy. These key issues are discussed and the paper concludes where it began by emphasising the need to build innovation policy on the explicit recognition that innovation results from the blending of two processes, invention and entrepreneurship, and that viable innovation policy can never be created unless entrepreneurial process is properly understood and addressed.

Policy framework for a knowledge society : families and knowledge

My thesis examines the link between families, harm and knowledge in a society where knowledge is increasingly the central organising principle (Bohme 1997: 449-450; Stehr 1994: 6), and represents the capacity for action (Stehr 1994: 8). I observed as a consultant in the 1990s that practitioners in family work were able to articulate what works but often unable to articulate why and therefore unable easily to replicate what works. This time coincided with increasing commentary on complexities of living, capacity of families to cope, identification of the scale of family harm, and use of the term 'the knowledge society'. My aim is to identify why what works, works with families exhibiting harmful behaviours and families acquiring knowledge from learning everyday life skills so as to lead less harmful and more fulfilling lives. And by such explanations inform, replicate and scale up practice to benefit more families exhibiting harm. I conceptualise the outcome as a sequence of family, community and policy work in an ecological framework (Bronfenbrenner 1979) within a knowledge society. My method was a year-long action research project with a family support service in New South Wales. I engaged in reflective practice with workers, and a parallel literature review that supported additional reflective practice. I found growing complexity of life requires growing knowledge. I found a distinction between everyday and abstract life worlds, and with families principally acting in the everyday life world. It is a world from which some families and their members seek to escape, often by means of harmful behaviours of neglect, abuse and violence. I substantiated the link that the family support service of my study sees between relationships, behaviours and affects; and I linked this in turn with its therapeutic engagement of the whole family — adults and children, male and female, victims and perpetrators. This engagement involves a process of learning (Rogers 1967: 280) to acquire fulfilling behaviours. It is a process of adult and experiential learning of relationship skills, drawing on under-used reserves of families. Relationship skills form a basis of acquiring other life skills since most require relationships with others to perform life skills. Combining the sequence of family, community and policy work with workers engaging in reflective practice of their work creates capacity for community institutions to replicate and scale up what works and why. Understanding this sequence may assist community institutions to inform policymakers of benefits common to all policy interests of such replication and scaling up. I conceptualise a policy framework of families and knowledge in a knowledge society and two lower level frameworks of process and content of life skills. Implications of these for practice, policy, and theory include a greater distinction between everyday and abstract knowledge and skills; recognition of a sequential process of information, learning, and knowledge; and inclusiveness and fluidity in learning in diverse adult learning settings and in family support professions.

Public and stakeholder values and knowledge of wildlife in Victoria, Australia

Prompted by a lack of human dimensions research in Australia, this study investigated the values and knowledge relating to wildlife held by members of the public within distinct demographic subsets of the Victorian population and members of wildlife management stakeholder groups; and compared these characteristics with how Victorian wildlife managers perceive these groups. A combination of semi-structured interviews and postal questionnaires were used. Fifteen in-depth interviews were conducted to explore how wildlife managers perceive the values and knowledge of wildlife held by members of various subsets of the Victorian population. A total of 1,431 questionnaires were completed by members of 13 public and stakeholder groups throughout Victoria, and these were analysed to explore values and knowledge relating to wildlife in Victoria. The findings of this study suggest that Victorian people have a strong emotional attachment to individual animals (the humanistic value), and an interest in learning about wildlife (the curiosity/learning/interacting value). The dominionistic/wildlife-consumption, utilitarian-habitat, aesthetic and negativistic values were not expressed by the majority of respondents from the public samples. The data also suggest that Victorian people have relatively low levels of factual knowledge about Australian wildlife. Thus, wildlife managers should expect support for wildlife management objectives that reflect the strong humanistic orientation of Victorians and tailor management and education programs to appeal to this value and Victorians' interest in learning about wildlife. Members of the Field Naturalists Club of Victoria (FNCV), Bird Observers Club of Australia (BOCA), Australian Conservation Foundation (ACF) stakeholder groups and management agency Parks Victoria expressed a strong interest in learning about wildlife. Members of the Royal Society for the Prevention of Cruelty to Animals (RSPCA) obtained high humanistic value scores; and members of the Victorian Field and Game Association (VFGA) obtained high domimomstic/wildlife-consumption value scores. Importantly, the humanistic and curiosity/learning/interacting values were the most strongly expressed values in all six groups and these values could be the key to more effective communication and collaboration between groups. Relationships between demographic factors, and values and knowledge relating to wildlife were found. For example, rural Victorians held a stronger dominionistic/ wildlife-consumption value than urban Victorians; females held stronger humanistic, curiosity/learning/interacting and negativistic values than males; young Victorians (18-34 years) held a lower curiosity/learning/interacting value and lower factual knowledge of wildlife than older Victorians; and more highly educated Victorians were more knowledgeable about wildlife than people with less formal education. No statistically significant differences were found between the values and knowledge of wildlife held by different income classes. While relationships between demographic factors, and values and knowledge relating to wildlife were found, they were generally much smaller than expected based on wildlife managers' perceptions and previous research. For example, the results suggest that Victorian females have a slightly stronger humanistic value of wildlife than males do. However, the important message emerging from the data is that males and females both express a strong emotional attachment to individual animals. Importantly, the results indicate that the effects of demographic factors on values and knowledge relating to wildlife are not always consistent across different geographic locations and stakeholder groups. For example, the slightly stronger interest in learning about wildlife among females when compared with males was observed in the rural and urban-fringe samples but not in the urban samples. This suggests that caution must be used when generalising the findings from human dimensions studies from one type of community or stakeholder group to another. Management programs should be tailored to the specific characteristics of the target audience. The findings also indicate that Victorian wildlife managers have diverse perceptions about the values and knowledge of wildlife held by members of different publics and stakeholder groups, and that the perceptions held by wildlife managers are not always consistent with the actual values and knowledge of wildlife held by members of different publics and stakeholders. For example, counter to the perceptions expressed by the interviewed wildlife managers, the interest in and factual knowledge of wildlife held by members of voluntary conservation groups equalled or surpassed that of wildlife managers; young Victorian adults (18-34 years) held a slightly lower curiosity/learning/interacting value and slightly lower level of factual knowledge of wildlife than older Victorians; and rural and urban communities in Victoria held low dominionistic and utilitarian values. Such discrepancies highlight the importance of investigating the actual values and knowledge held by members of such groups, so that appropriate and effective wildlife management programs can be implemented. Inaccurate perceptions and assumptions may contribute to ineffective communication between managers, stakeholders and publics; and adversely effect the success of wildlife management programs.

Re-visioning research and knowledge for the 21st century

The article discusses various reports published within the issue including one on the importance of re-visioning research and another on theoretical perspective for analysing television.

Attitudes and knowledge of shade-coffee farmers towards vertebrates and their ecological functions.

The purpose of this study was to assess farmers’ attitudes, as well as perceptions and knowledge that shape those attitudes, toward the ecological role of vertebrates inhabiting shaded-coffee farms. We also aimed to determine whether differences existed among two groups of farmers: one that had attended environmental education workshops, and one that had not. We conducted 36 oral interviews of farmers in the region of Cuetzalan, Mexico. All farmers were members of an important regional cooperative, Tosepan Titataniske. In general, farmers’ attitudes towards birds were positive. Snakes were perceived as useful but dangerous animals. Attitudes towards nonflying mammals were mostly indifferent. Bats were poorly understood and badly perceived. Seed dispersal was perceived as an important ecological function performed by animals. Pollination was also perceived as important, but to a lesser degree. Knowledge about ecological functions was high for seed dispersal, and low for pollination. We found a positive correlation between attendance of educational workshops and the presence of “environmentally-friendly” attitudes, perceptions, and knowledge. However, a cause-effect relationship could not be clearly established. We suggest that environmental education programs include the objective of increasing the knowledge of people about the ecological functions played by different groups of animals that live in agroecosystems. Particular efforts should be directed toward improving the way in which certain non-charismatic groups of animals, such as bats, are perceived.

Inclusive policy action : exploring the realities and knowledge of teachers implementing inclusive education

Inclusive Policy Action recognizes the complexity of inclusive policy for teachers. However, the author presents a strong view that a constructive approach for future action can be accomplished by drawing on teachers' own accounts of the significant characteristics contributing to effective inclusion. Accordingly, teachers' work is recognized as a vital contributing factor to successful inclusion, despite the often over-powering emphasis on additional funding. For this reason the finer structures of changed pedagogy, the development of teacher knowledge and the vision of quality education for all students are explored using teachers' own voice to theorize and analyze the actuality of successful inclusive practice. The emergent characteristics relate to the importance of communicative infrastructures promoting knowledge within learning communities rather than political directives associated with inclusive education policy. These characteristics draw attention to the need to reconsider and revalue the knowledge and expertise generated by education policy actors, namely the teachers and school administrators involved in institutional planning and practice.

Mixed transfer function neural networks for generalization and knowledge extraction

This thesis develops a novel framework of nonlinear modelling to adaptively fit the complexity of the model to the problem domain resulting in a better modelling capability and a straightforward knowledge acquisition. The developed framework also permits increased comprehensibility and user acceptability of modelling results.

Firm survival through a crisis : the influence of market orientation, marketing innovation and business strategy

As an outcome of the economic crisis, the global manufacturing sector is collapsing. Focusing on Chinese manufacturing small and medium enterprises (SMEs), this study investigates whether marketing innovation, defined as improvements in the marketing mix, can assist in withstanding the challenges of operating under the current economic conditions. A conceptual model linking market orientation, marketing innovation, competitive advantage and firm survival is tested using structural equation modelling. Three key findings are derived. First, the examined Chinese manufacturing SMEs had a greater perceived likelihood of survival had they developed and sustained a competitive advantage. Second, marketing innovation assisted in developing and sustaining competitive advantages based on differentiation and cost leadership strategies. Third, marketing innovation capabilities improved when the examined manufacturing SMEs were competitor oriented and had good inter-functional capabilities.

Practice nurses' role and knowledge about diabetes management within rural and remote Australian general practices

Background: The increasing prevalence of diabetes and obesity represents a significant disease burden in Australia. Practice nurses (PNs) play an important role in diabetes education and management.

Aim: To explore PNs' roles, knowledge and beliefs about diabetes education and management in rural and remote general practice in Australia.

Method: Exploratory study undertaken in three phases: 1) Pilot study to test the performance of the questionnaire; 2) One-shot cross-sectional survey using self-complete questionnaires; 3) Individual interviews.

Results: Ten PNs completed the pilot test; the draft questionnaire was deemed appropriate to the study purpose. Then, 65 questionnaires were distributed to PNs and 21 responded. Fourteen respondents had worked in the role <5 years, and most PNs attended diabetes education programmes in their workplace. A minority (40%) used diabetes management guidelines regularly. Most knew obesity to be the most common risk factor for diabetes but only 50% knew that glycosylated haemoglobin indicates blood glucose levels over the preceding three months. Self-reported competency to assess patients' self-care practices and medication management practices varied.

Conclusion: PNs' diabetes management was self-reported; their knowledge varied and their perceived benefits of diabetes education differed from those of patients.