Slurry pump side-liner wear : comparison of some laboratory and field results

The current work compares some slurry pump lab wear results with the wear found across different field applications with d₈₅ particle size ranging from 100 to 4000mm. Side-liner wear life data has been collected for two different impeller geometries and two different material classes (cast iron and natural rubber). Different field wear patterns have been photographed and categorised on the basis of particle size. The field wear patterns showed close similarity to the lab wear patterns particularly in the areas of localised gouging. Wear rates are also compared for the different geometries. Overall trend of wear with particle size for the white iron parts was similar to the grey iron lab tests albeit at significantly lower wear rates. In general, the wear with the rubber side-liner was less at smaller particle sizes but greater for particles larger than d8The current work compares some slurry pump lab wear results with the wear found across different field applications with d₈₅ particle 10 size ranging from 100 to 4000mm. Side-liner wear life data has been collected for two different impeller geometries and two different 11 material classes (cast iron and natural rubber). Different field wear patterns have been photographed and categorised on the basis of particle 12 size. The field wear patterns showed close similarity to the lab wear patterns particularly in the areas of localised gouging. Wear rates are 13 also compared for the different geometries. Overall trend of wear with particle size for the white iron parts was similar to the grey iron lab 14 tests albeit at significantly lower wear rates. In general, the wear with the rubber side-liner was less at smaller particle sizes but greater for 15 particles larger than d₈₅ of about 700mm. © 2001 Elsevier Science B.Y. All rights reserved.

Comparative sexuality of conspecific stream-side and stream-rock mosses

The sexuality of conspecific stream-rock and stream-side bryophytes at Cement Creek in the Yarra Ranges National Park, Victoria, Australia was examined in terms of sex ratios and sporophyte production. Generally, stream-side colonies had higher numbers of stems, inflorescences and gametangia than their stream-rock counterparts. A higher number of stream-side than stream-rock species produced sporophytes although Cyathophorum bulbosum (Hedw.) Mull.Hai. produced more sporophytes on stream-rocks than in the stream-side habitat. Sex ratios generally showed a female bias with regard to stem numbers and number of inflorescences.

Depression and expression: life begins on the other side of despair

This paper has two parts. In Part I, it consists of a letter written by the subject of the ‘case study’ that forms the basis of Part II. Part I demonstrates how the writer Aliki Pavlou discovered that, in attempting to help a friend face uncomfortable truths in relation to his perception of his mother, she inadvertently was able to voice her own dilemma in relation to her mother that hitherto had been elusive.
This paper forms a part of a larger project being researched by Aliki Pavlou, Justin Clemens and me. The study, to be entitled, "In the Heart of Hell: Depression and its Expression," is one that contends that Literature expresses the ineffable nature of depression in its symbolic mode; that, indeed, literary texts reveal in their concealment. The work therefore argues that ‘depression’ is expressible.
Part II of this paper analyses the response of a depressive to Jean-Paul Sartre’s novel Nausea (1964). Beginning with a brief discussion of the role of the ‘mother’ as psychologically pivotal in some depressives’ struggle towards well-being, this section analyses a reading of Nausea by a depressive. The objective of this study was to ascertain the extent to which the condition of nausea, as represented in Sartre’s novel, expresses the experience of depression.

Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophsphamide therapy in patients with systemic lupus erythematosus

Aims
Cyclophosphamide (CTX) is an established treatment of severe systemic lupus erythematosus (SLE). Cytotoxic CTX metabolites are mainly detoxified by multiple glutathione S-transferases (GSTs). However, data are lacking on the relationship between the short-term side-effects of CTX therapy and GST genotypes. In the present study, the effects of common GSTM1, GSTT1, and GSTP1 genetic mutations on the severity of myelosuppression, gastrointestinal (GI) toxicity, and infection incidences induced by pulsed CTX therapy were evaluated in patients SLE.
Methods
DNA was extracted from peripheral leucocytes in patients with confirmed SLE diagnosis (n = 102). GSTM1 and GSTT1 null mutations were analyzed by a polymerase chain reaction (PCR)-multiplex procedure, whereas the GSTP1 codon 105 polymorphism (Ile→Val) was analyzed by a PCR-restriction fragment length polymorphism (RFLP) assay.
Results
Our study demonstrated that SLE patients carrying the genotypes with GSTP1 codon 105 mutation [GSTP1*-105I/V (heterozygote) and GSTP1*-105 V/V (homozygote)] had an increased risk of myelotoxicity when treated with pulsed high-dose CTX therapy (Odds ratio (OR) 5.00, 95% confidence interval (CI) 1.96, 12.76); especially in patients younger than 30 years (OR 7.50, 95% CI 2.14, 26.24), or in patients treated with a total CTX dose greater than 1.0 g (OR 12.88, 95% CI 3.16, 52.57). Similarly, patients with these genotypes (GSTP1*I/V and GSTP1*V/V) also had an increased risk of GI toxicity when treated with an initial pulsed high-dose CTX regimen (OR 3.33, 95% CI 1.03, 10.79). However, GSTM1 and GSTT1 null mutations did not significantly alter the risks of these short-term side-effects of pulsed high-dose CTX therapy in SLE patients.
Conclusions
The GSTP1 codon 105 polymorphism, but not GSTM1 or GSTT1 null mutations, significantly increased the risks of short-term side-effects of pulsed high-dose CTX therapy in SLE patients. Because of the lack of selective substrates for a GST enzyme phenotyping study, timely detection of this mutation on codon 105 may assist in optimizing pulsed high-dose CTX therapy in SLE patients.

A theory of injustice: the flip side of the relocation coin in Australia

Problems attached to relocation cases in Australia because of geographical and cultural reasons - the best interests of the child principle inherently promotes injustice in relocation cases - operation of Part VII of the Family Law Act in the context of relocation cases - assessment of the best interests of the child principle in Australian relocation cases - responsibility of contact parents - reforming Australian law to promote an equality of interests.