W.W. Tyrrill receipt, June 1888

A receipt from W.W. Tyrrill, of St. Catharines, Ontario dated June 2, 1888, for a ladies Swiss watch priced at $11.00. The receipt is a rental agreement which specifies the terms of a fee payment schedule. Information on the receipt indicates Mr. Tyrrill sold watches, jewelry, silver plated goods, albums and Bibles. He is also listed as an agent for pianos, organs and Singer sewing machines. This receipt was in the possession of Iris Sloman Bell, of St. Catharines. Relatives of the Sloman Bell families include former Black slaves from the United States who settled in southern Ontario.There are various spellings of the Tyrrill name within the Bell family archive. Other forms of the name include Tyrell, Tyrrell, and Terrell.

Decoding algorithms using side-effect machines

Bioinformatics applies computers to problems in molecular biology. Previous research has not addressed edit metric decoders. Decoders for quaternary edit metric codes are finding use in bioinformatics problems with applications to DNA. By using side effect machines we hope to be able to provide efficient decoding algorithms for this open problem. Two ideas for decoding algorithms are presented and examined. Both decoders use Side Effect Machines(SEMs) which are generalizations of finite state automata. Single Classifier Machines(SCMs) use a single side effect machine to classify all words within a code. Locking Side Effect Machines(LSEMs) use multiple side effect machines to create a tree structure of subclassification. The goal is to examine these techniques and provide new decoders for existing codes. Presented are ideas for best practices for the creation of these two types of new edit metric decoders.

A Multi-Objective Genetic Algorithm with Side Effect Machines for Motif Discovery

Understanding the machinery of gene regulation to control gene expression has been one of the main focuses of bioinformaticians for years. We use a multi-objective genetic algorithm to evolve a specialized version of side effect machines for degenerate motif discovery. We compare some suggested objectives for the motifs they find, test different multi-objective scoring schemes and probabilistic models for the background sequence models and report our results on a synthetic dataset and some biological benchmarking suites. We conclude with a comparison of our algorithm with some widely used motif discovery algorithms in the literature and suggest future directions for research in this area.

Business Card - Singer Sewing Machine Co.

Two business cards for Singer Sewing Machine Co. Incorporated located at 269 St. Paul Street, St. Catharines. One card has the name of a representative for the company, ? Cowan.

Article - "Those darling young women in their flying machines", 1977

A retrospective article written by Dorothy Rungeling as she recalls the the International Air Races that often began or ended in Welland-Port Colborne Airport. The article was published in the Welland Evening Tribune, 9 September 1977.

Receipt from James D. Tait for sewing supplies, quilts and curtains

Receipt from James D. Tait for sewing supplies, quilts and curtains, April 1887.