Registro de incidencias : seguridad en ficheros automatizados. Protección de datos de carácter personal (DD.CC.PP.)

El proyecto de Registro Automatizado de Incidencias tiene como objeto el desarrollo de un software que permita realizar el procedimiento de notificación, gestión y respuesta ante las incidencias. Se considerarán como "incidencias de seguridad", entre otras, cualquier incumplimiento de la normativa desarrollada en el Documento de Seguridad, así como a cualquier anomalía que afecte o pueda afectar a la seguridad de los datos de carácter personal.

Politics and the Olympics: some new dimensions

Paper given at the Institut de Ciències Polítiques i Socials, Barcelona in 1995 analysing the relationship between politics, the Olympic Games and the Olympic Movement and their influences.

Combinatorial Synthesis and Biological Evaluation of Inhibitors of D-Ala-D-Ala-Ligase

Report for the scientific sojourn carried out at the Max Planck Institut of Molecular Phisiology, Germany, from 2006 to 2008.The work carried out during this postdoctoral stage was focused on two different projects. Firstly, identification of D-Ala D-Ala Inhibitors and the development of new synthethic approaches to obtain lipidated peptides and proteins and the use of these lipidated proteins in biological and biophysical studies. In the first project, new D-Ala D-Ala inhibitors were identified by using structural alignments of the ATP binding sites of the bacterial ligase DDl and protein and lipid kinases in complex with ATP analogs. We tested a series of commercially available kinase inhibitors and found LFM-A13 and Tyrphostine derivatives to inhibit DDl enzyme activity. Based on the initial screening results we synthesized a series of malononitrilamide and salicylamide derivatives and were able to confirm the validity of these scaffolds as inhibitors of DDl. From this investigation we gained a better understanding of the structural requirements and limitations necessary for the preparation of ATP competitive DDl inhibitors. The compounds in this study may serve as starting points for the development of bi-substrate inhibitors that incorporate both, an ATP competitive and a substrate competitive moiety. Bisubstrate inhibitors that block the ATP and D-Ala binding sites should exhibit enhanced selectivity and potency profiles by preferentially inhibiting DDl over kinases. In the second project, an optimized synthesis for tha alkylation of cysteins using the thiol ene reaction was establisehd. This new protocol allowed us to obtain large amounts of hexadecylated cysteine that was required for the synthesis of differently lipidated peptides. Afterwards the synthesis of various N-ras peptides bearing different lipid anchors was performed and the peptides were ligated to a truncated N-ras protein. The influence of this differently lipidated N-ras proteins on the partioning and association of N-Ras in model membrane subdomains was studied using Atomic Force Microscopy.

Captant la recerca : interconnexió entre el repositori institucional (Dipòsit Digital UB) i el Gestor de RECerca (GREC)

Un dels objectius del repositori institucional de la Universitat de Barcelona, el Dipòsit Digital (DD), és difondre en obert els resultats de la recerca dels investigadors de la universitat, principalment els publicats en revistes científiques. Per fer-ho possible es necessari treballar conjuntament amb les aplicacions ja existents a la UB i especialment amb el gestor de la recerca, GREC. &br& &br& En aquesta comunicació es presenta el projecte d'interconnexió entre el DD i el GREC. La finalitat és que qualsevol investigador de la UB introdueixi, una única vegada, les dades referents a qualsevol publicació resultant de la seva recerca, incloent-hi el document corresponent, i que aquesta informació i aquest material estigui a l'abast de tothom des del repositori.

Un nou desenvolupament en el préstec interbibliotecari del CBUC

L'increment d'ús del préstec interbibliotecari i l'obtenció de documents (PI/SOD) obria, en el si del Consorci de Biblioteques Universitàries de Catalunya, un debat de com millorar la seva accessibilitat i gestió, especialment de cara a l'usuari que havia d'utilitzar diferents aplicatius en el procés de sol·licitar documents en PI/SOD. Fruit d'aquesta reflexió, s'ha realitzat un nou pas en la millora i consolidació d'aquest servei, integrant dins de la interfície de consulta per web del Catàleg Col·lectiu de les Universitats de Catalunya la possibilitat de demanar els documents en línia tant sols entrant la identificació d'usuari. L'Aplicació desenvolupada en PL-SQL per la Universitat Oberta de Catalunya dins del projecte GALA (Global Access to Local Applications and services), permet la captura automàtica de les dades del registre bibliogràfic i la seva exportació al formulari de PI/SOD de la institució a la que pertany l'usuari, generant una comanda que finalment és validada per la institució.

Bases neuroestructurals i neurofuncionals de la discalcúlia del desenvolupament

La discalcúlia del desenvolupament (DD) és un trastorn de l'aprenentatge que afecta a la correcta adquisició i execució de les habilitats aritmètiques, i que comporta una discrepància entre la capacitat per al càlcul i el quocient d'intel•ligència. La prevalença és d'un 3 a un 6%, similar a la d'altres trastorns del desenvolupament. Existeix comorbilitat de la DD amb altres trastorns del desenvolupament: amb la dislèxia en un 17% i amb el trastorn per dèficit d'atenció/hiperactivitat en un 20%. Es creu que l'origen neural de la DD es localitzaria al lòbul parietal, i en concret, estudis actuals de neuroimatge recolzen el solc intraparietal (IPS) com la regió clau del processament aritmètic. Tot i així, també hi participarien altres regions cerebrals, com el lòbul prefrontal. L'objectiu del nostre projecte és aprofundir en els dèficits anatòmics i funcionals associats als dèficits numèrics en persones amb discalcúlia pura, amb DD associada a dislèxia i amb DD associada a TDA/H. La determinació de diferents patrons de dèficits neurals i de rendiment cognitiu, en aquests tres grups de pacients, ajudaria a l'elaboració de programes de reeducació més específics, i repercutiria positivament en el tractament de la DD. En el present estudi, s'evaluaren neuropsicològicament i mitjançant ressonància magnètica funcional 22 nens i nenes amb DD pura i cómorbida amb dislèxia i TDA/H. En el present moment, l'estudi es troba a la fase de recollida de dades.

Influència dels desitjos, les necessitats i les xarxes familiars i d’amistat dels estudiants universitaris de la UAB en els seus itineraris formatius en els estudis superiors

L’objectiu del treball és ajudar a la descripció del fenomen del canvi en els itineraris formatius superiors dels estudiants. L’anàlisi es realitza a partir de dades empíriques generades a la UAB durant l’any 2012 i en base als factors contextuals – socio-demogràfics, de perfil i context de l’estudiant – i motivacionals – de vocació acadèmica, vocació laboral, resultats acadèmics, condicions facilitadores, condicions d’empleabilitat, condicions econòmiques, influència de les amistats, estratègies adaptatives o d’oportunitat – que influeixen en les decisions de canvi dels estudiants. En les conclusions es reflexiona sobre les polítiques orientades a mantenir l’equitat en l’accés i en la permanència dels estudiants.

Relativistic mean-field interaction with density-dependent meson-nucleon vertices based on microscopical calculations

Although ab initio calculations of relativistic Brueckner theory lead to large scalar isovector fields in nuclear matter, at present, successful versions of covariant density functional theory neglect the interactions in this channel. A new high-precision density functional DD-MEδ is presented which includes four mesons, σ, ω, δ, and ρ, with density-dependent meson-nucleon couplings. It is based to a large extent on microscopic ab initiocalculations in nuclear matter. Only four of its parameters are determined by adjusting to binding energies and charge radii of finite nuclei. The other parameters, in particular the density dependence of the meson-nucleon vertices, are adjusted to nonrelativistic and relativistic Brueckner calculations of symmetric and asymmetric nuclear matter. The isovector effective mass mp*−mn* derived from relativistic Brueckner theory is used to determine the coupling strength of the δ meson and its density dependence.

Catàleg de plantes vasculars endèmiques, rares o amenaçades de Catalunya. I. Tàxons endèmics

Catalogue of endemic, rare or threatened vascular plants in Catalonia. I. Endemic taxa. This is the first of a set of papers devoted to rare or threatened plants in Catalonia. We list 279 specific or subspecific taxa which are in a broad sense endemic to the northeastern part of the Iberian Peninsula. We assess them with regard to their conservation status according to IUCN criteria. Assignment of these taxa to established categories has led to the following results: 6 taxa critically endangered (CR), 5 endangered (EN), 32 vulnerable (VU), 5 near threatened (LR nt). 84 least concern (LR lc), 116 not threatened (NT) and 31 data deficient (DD). The small number of taxa that enjoy legal protection in comparison with the number of threatened plants is emphasized. Key words: Endemic plants, Catalonia, Plant conservation, UICN categories.

Conditional maximum likelihood timing recovery: estimators and bounds

This paper is concerned with the derivation of new estimators and performance bounds for the problem of timing estimation of (linearly) digitally modulated signals. The conditional maximum likelihood (CML) method is adopted, in contrast to the classical low-SNR unconditional ML (UML) formulationthat is systematically applied in the literature for the derivationof non-data-aided (NDA) timing-error-detectors (TEDs). A new CML TED is derived and proved to be self-noise free, in contrast to the conventional low-SNR-UML TED. In addition, the paper provides a derivation of the conditional Cramér–Rao Bound (CRB ), which is higher (less optimistic) than the modified CRB (MCRB)[which is only reached by decision-directed (DD) methods]. It is shown that the CRB is a lower bound on the asymptotic statisticalaccuracy of the set of consistent estimators that are quadratic with respect to the received signal. Although the obtained boundis not general, it applies to most NDA synchronizers proposed in the literature. A closed-form expression of the conditional CRBis obtained, and numerical results confirm that the CML TED attains the new bound for moderate to high Eg/No.

Probabilistic algorithms for blind adaptive multiuser detection

In this paper, two probabilistic adaptive algorithmsfor jointly detecting active users in a DS-CDMA system arereported. The first one, which is based on the theory of hiddenMarkov models (HMM’s) and the Baum–Wech (BW) algorithm,is proposed within the CDMA scenario and compared withthe second one, which is a previously developed Viterbi-basedalgorithm. Both techniques are completely blind in the sense thatno knowledge of the signatures, channel state information, ortraining sequences is required for any user. Once convergencehas been achieved, an estimate of the signature of each userconvolved with its physical channel response (CR) and estimateddata sequences are provided. This CR estimate can be used toswitch to any decision-directed (DD) adaptation scheme. Performanceof the algorithms is verified via simulations as well as onexperimental data obtained in an underwater acoustics (UWA)environment. In both cases, performance is found to be highlysatisfactory, showing the near–far resistance of the analyzed algorithms.

Health-related quality of life in patients with dual diagnosis: clinical correlates

Background: Although the studies published so far have found an affectation in the Health Related Quality of Life (HRQOL) in both psychiatric and substance use dependence disorders, very few studies have applied HRQOL as an assessment measure in patients suffering both comorbid conditions, or Dual Diagnosis. The aim of the current study was to assess HRQOL in a group of patients with Dual Diagnosis compared to two other non-comorbid groups and to determine what clinical factors are related to HRQOL. Methods: Cross-sectional assessment of three experimental groups was made through the Short Form 36 Item Health Survey (SF-36). The sample consisted of a group with Dual Diagnosis (DD; N=35), one with Severe Mental Illness alone (SMI; N=35) and another one with Substance Use Dependence alone (SUD; N=35). The sample was composed only by males. To assess the clinical correlates of SF-36 HRQOL, lineal regression analyses were carried out. Results: The DD group showed lower scores in most of the subscales, and in the mental health domain. The group with SUD showed in general a better state in the HRQOL while the group with SMI held an intermediate position with respect to the other two groups. Daily medication, suicidal attempts and daily number of coffees were significantly associated to HRQOL, especially in the DD group. Conclusions: The DD group showed lower self-reported mental health quality of life. Assessment of HRQOL in dual patients allows to identify specific needs in this population, and may help to establish therapeutic goals to improve interventions.

Patología Dual y rasgos de personalidad:situación actual y líneas futuras de trabajo

Dual diagnosis (DD) is the co-occurrence, in the same person, of a mental disorder (MD) and a substance use disorder (SUD). Nowadays, the study of the personality with DD is realized mainly from a categorical view, focusing on the detection of personality disorders and not on the traits associated to DD and the possible differential profile compared to those patients with only MD or SUD. Studies analyzing personality traits of patients with DD and their possible differential profile are very limited. However, existing data indicates that DD patients show higher levels of Sensation Seeking, Impulsivity, Harm Avoidance and Neuroticism; and lower levels of Persistence, Self-Direction, Self-Transcendence and Cooperation. Therefore, DD is associated to personality characteristics that suggest more disruptive behaviors, fewer resources for recovering and keeping abstinent and worse prognosis compared to those with only one disorder. Progress in the characterization of personality traits in DD, taking into consideration the methodological aspects to be improved could allow better adaptation of the integrated treatment of these patients in the future.