La colección Marca Hispanica, un ambicioso proyecto de traducción de José Agustín Goytisolo

In May 1985 José Agustín Goytisolo launched an ambitious project to translate into Spanish works originally written in Catalan. To this end, with a small group of collaborators he founded the Marca Hispanica collection. Its aim was to spread Catalan literature beyond its borders to reach millions of readers of Spanish through schools, teachers and language academies around the world. The initial idea was to make available in bilingual editions a hundred representative works of Catalan literature but, in the event, only twenty-two volumes were ever published. Based on access to unpublished documents, in this article we defend this endeavour, report on its progress and relate the circumstances, beyond the control of the participants, that led to its demise.

Antonio Agustín, Bologna e l’antiquaria del Cinquecento

One of the founders of numismatics in Modern Age was the archbishop of Tarragona and renowned jurist Antonio Agustín. He was educated during the mid-sixteenth century mainly in Italy, particularly in Bologna and Padua. His role in the development of antiquarian studies – and interest in collecting – ran parallel to the development of numismatics in the Cinquecento. His interest in realia , i.e., the materials and documents perceived as primary evidence of history understood in a global sense, make him a pioneer in setting the trends and methodologies which would be later employed by Bernard de Montfaucon. The period Antonio Agustín spent in Bologna, at the Reale Collegio di Spagna, between 1539 and 1544, afforded him the opportunity to enter a very cultivated circle where the admiration and study of the Antique was well established since the mid-fifteenth century. The cultural effervescence taking place in Bologna was encouraged by the court of Giovanni II Bentivoglio and the University alike. Artists also contributed to the development of antiquarian knowledge, and the painter Amico Aspertini (ca. 1475-1552) exemplifies this. It is clear that Antonio Agustín certainly benefited from the scholarly environment in Bologna during the first half of the Cinquecento, which had been firmly anchored since the fertile Quattrocento. Although the documentary evidence is scarce, and it is difficult to pinpoint the details, it is undeniable that Antonio Agustín was heavily influenced by his Bolognese experience.

¿Cómo definen los profesionales de enfermería hospitalarios sus competencias asistenciales?

Objetivos: Este artículo tiene un doble objetivo: presentar la segunda parte del marco conceptual empleado en el desarrollo del proyecto COM VA© y los resultados del proceso de definición de un instrumento de competencias asistenciales del profesional de enfermería en el ámbito hospitalario, que enfatiza la participación de los profesionales, la reflexión crítica individual y grupal, y el compromiso profesional. El marco conceptual explora los significados de los términos toma de decisiones y ámbito de responsabilidad, competencias, estándares y normas de la práctica, dominio competencial, elemento competencial y matriz de competencias. Material y método: Para el proceso de definición del marco competencial se empleó el modelo de investigación-acción participativa. La muestra incluyó a 487 profesionales de enfermería hospitalarios. Los resultados del análisis definen el ámbito de competencias asistenciales en 6 dominios: 1) cuidar al enfermo; 2) valorar, diagnosticar y abordar situaciones clínicas cambiantes; 3) ayudar al enfermo a cumplir el tratamiento; 4) contribuir a garantizar la seguridad y el proceso asistencial; 5) facilitar el proceso de adaptación y afrontamiento, y 6) trabajar en equipo y adaptarse a un entorno cambiante. Cada dominio queda finalmente definido por 5 elementos competenciales que explican su significado. Cada elemento competencial contiene una definición que incluye las principales intervenciones y actuaciones enfermeras que lo configuran y las conductas que conforman los criterios de valoración de la ejecución competencial.

Total synthesis of (-)-isoavenaciolide

An enantioselective approach to (-)-isoavenaciolide was achieved starting from 1- undecyn-3-ol. The synthesis relied upon the preparation of a chiral 4-silyloxy-2-alkenylborane by hydroboration of a protected 2,3-allenol and subsequent stereoselective addition to 2- thiophenecarboxaldehyde

Un curriculum vitae de Martín García de Mendoza dictat per ell mateix

En aquest article, s"hi presenta la transcripció de dos documents ja coneguts, però inèdits: el testament i la petició de ciutadania honrada de Martín García de Mendoza, mestre major de l"obra de la seu de Tortosa entre 1581 i 1615. La lectura d"aquests textos permet fer diverses precisions sobre la formació, les influències i les idees que l"arquitecte tenia sobre el seu ofici.

Promoter DNA Hypermethylation and Gene Repression in Undifferentiated Arabidopsis Cells

Maintaining and acquiring the pluripotent cell state in plants is critical to tissue regeneration and vegetative multiplication. Histone-based epigenetic mechanisms are important for regulating this undifferentiated state. Here we report the use of genetic and pharmacological experimental approaches to show that Arabidopsis cell suspensions and calluses specifically repress some genes as a result of promoter DNA hypermethylation. We found that promoters of the MAPK12, GSTU10 and BXL1 genes become hypermethylated in callus cells and that hypermethylation also affects the TTG1, GSTF5, SUVH8, fimbrin and CCD7 genes in cell suspensions. Promoter hypermethylation in undifferentiated cells was associated with histone hypoacetylation and primarily occurred at CpG sites. Accordingly, we found that the process specifically depends on MET1 and DRM2 methyltransferases, as demonstrated with DNA methyltransferase mutants. Our results suggest that promoter DNA methylation may be another important epigenetic mechanism for the establishment and/or maintenance of the undifferentiated state in plant cells.