Total synthesis of (-)-isoavenaciolide


Autoria(s): Santos, David; Ariza Piquer, Xavier; García Gómez, Jordi; Lloyd-Williams, Paul; Martínez Laporta, Agustín; Sánchez Zarzalejo, Carolina
Contribuinte(s)

Universitat de Barcelona

Resumo

An enantioselective approach to (-)-isoavenaciolide was achieved starting from 1- undecyn-3-ol. The synthesis relied upon the preparation of a chiral 4-silyloxy-2-alkenylborane by hydroboration of a protected 2,3-allenol and subsequent stereoselective addition to 2- thiophenecarboxaldehyde

Identificador

http://hdl.handle.net/2445/43586

Idioma(s)

eng

Publicador

American Chemical Society

Direitos

(c) American Chemical Society , 2013

info:eu-repo/semantics/openAccess

Palavras-Chave #Biomolècules #Productes naturals #Síntesi asimètrica #Medicaments antibacterians #Fungicides #Biomolecules #Natural products #Asymmetric synthesis #Antibacterial agents #Fungicides
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/acceptedVersion