Assesing the political viability of labour market reform: The case of employment protection

We analyze the political support for employment protection legislation.Unlike my previous work on the same topic, this paper pays a lot ofattention to the role of obsolescence in the growth process.In voting in favour of employment protection, incumbent employeestrade off lower living standards (because employment protectionmaintains workers in less productive activities) against longer jobduration. The support for employment protection will then depend onthe value of the latter relative to the cost of the former. Wehighlight two key deeterminants of this trade-off: first, the workers'bargaining power, second, the economy's growth rate-more preciselyits rate of creative destruction.

The political economy of employment protection

This paper develops a model of job creation and job destruction in agrowing economy with embodied technical progress, that we use toanalyze the political support for employment protection legislationssuch as the ones that are observed in most European countries.We analyze the possibility of Condorcet cycles due to the fact thatworkers about to become unemployed prefer both an increase and areduction in firing costs over the status quo. Despite this problem, we show the existence of local, and sometimes global majority winners.In voting in favour of employment protection, incumbent employeestrade off lower living standards (because employment protectionmaintains workers in less productive activities) against longer job duration. We show that the gains from, and consequently the politicalsupport for employment protection (as defined by maximunjob tenure) are larger, the lower the rate of creative destruction and the largerthe worker's bargaining power. Numerical simulations suggest a hump-shaped response of firing costs to these variables, as well as negative impact of exogeneous turnover on employment protection.

A diagram of public spaces within urban landscape as a strategy for sustainable urban planning in Chinese cities

Destruction of historical urban fabric in many Chinese cities and towns, without the possibility of its recovery as an urban asset, leads us to consider alternative strategies and criteria for formulating new urban projects, using creative urban planning instruments and strategies to provide a sense of place and identity to the urban landscape. The challenge is to set up an urban structure that constitutes a spatial reference system, a structure consisting of a set of urban landmarks that construct a system of related public spaces, endowed with collective significance and identity. Such a network could include a wide variety of urban typologies and natural elements. An important result of this strategy would be the recovery of the social and cultural values attached to the natural landscape in Chinese civilization. Hangzhou city will be analyzed as a case study

Shear thinning and thixotropy of HMHEC and HEC water solutions

Steady state viscosity and thixotropy of hydrophobically modified hydroxyethyl cellulose HMHEC and nonassociative cellulose water solutions are studied. Although all the samples are shear thinning, only the HMHEC is thixotropic, since the migration of hydrophobes to micelles is controlled by diffusion. The Cross model fits steady state curves. The Mewis model, a phenomenological model that proposes that the rate of change of viscosity when the shear rate is suddenly changed is related to the difference between the steady state and current values of viscosity raised to an exponent, fits structure construction experiments when the exponent, n, is estimated to be around 2. The Newtonian assumption used by Mewis cannot be used here, however. This seems to be related to the fact that the thickening is due to bridged micelle formation, which is a slow process, and also to topological constraints and entanglements, which are rapid processes. The kinetic parameter was redefined to kn in order to make it independent of initial conditions. So, kn depends only on how the shear affects the structure. kn reaches a plateau at shear rates too low to produce structure destruction and decreases at higher shear rates.

Das Marzgefallenen-Denkmal. Monumento a los caidos de Marzo

Resumen: Walter Gropius desarrolla entre los años 1920 y 1922 un proyecto de monumento conocido como: Märzgefallenen-Denkmal (Monumento a los caídos de marzo). Se trata de un memorial dedicado a nueve obreros asesinados en Weimar, durante una manifestación en contra del Kapp Putsch (golpe de estado dirigido por Wolfgang Kapp). En el siguiente artículo se analiza la evolución del proyecto y de su implantación a través del análisis de la documentación gráfica de la obra. Observando muy especialmente las adaptaciones que transforman su diseño, condicionado por circunstancias externas. Nos hallamos ante un monumento de un gran valor histórico, político y social; capaz de una gran flexibilidad en la fase proyectual, y en cierto modo vestigio superviviente de todo un siglo. Abstract: Walter Gropius develops between the years 1920 and 1922 a monument known as: Märzgefallenen-Denkmal (Monument to the fallen of March). It is a memorial dedicated to nine workers killed in Weimar, during a demonstration against the Kapp Putsch (coup d'etat led by Wolfgang Kapp). The following article analyzes the evolution of the project and its implementation through analysis of the graphic documentation of the work. Noting especially the changes that transform the design, influenced by external circumstances. This is a monument of great historical, political and social interest; a work of art capable of great flexibility in its design stage, and the surviving vestige of a century. Palabras clave castellano: Monumento, política, destrucción, nazis Palabras clave inglés: Monument, politics, destruction, nazis

Alteraciones biológicas de la madera: el estudio de los materiales constructivos del yacimiento de Pleta de l'Estall Serrer (Valle del Madriu, Andorra)

El análisis antracológico, dendrológico y tafonómico de tres estructuras pastoriles de época moderna del yacimiento de Pleta de l’Estall Serrer (valle delMadriu, Andorra) situado a 1.980mde altitud, nosmuestra una presencia casi absoluta del pino tipo negro y la presencia puntual de taxones arbustivos como las ericáceas. Se trata de especies típicas en un bosque subalpino de pino negro. La presencia casi absoluta del pino, nos ha permitido observar diferentes alteraciones de la madera que nos han proporcionado una gran información sobre el uso de la madera, sobre todo las alteraciones por microorganismos. Hemos podido distinguir varios tipos de alteraciones causadas tanto por insectos xilófagos e hifas de hongos. Además, hemos identificado algunos individuos de termitas subterráneas tanto vivas como carbonizadas. Las primeras son termitas que atacan la madera arqueológica durante los procesos postdeposicionales y las termitas carbonizadas seguramente fueron la causa del deterioro de las estructuras y su posterior destrucción a través de su incendio.

The Protein quality control system manages plant defence compound synthesis

Jasmonates are ubiquitous oxylipin-derived phytohormones that are essential in the regulation of many development, growth and defence processes. Across the plant kingdom, jasmonates act as elicitors of the production of bioactive secondarymetabolites that serve in defence against attackers. Knowledge of the conserved jasmonate perception and early signalling machineries is increasing, but the downstream mechanisms that regulate defence metabolism remain largely unknown. Herewe showthat, in the legumeMedicago truncatula, jasmonate recruits the endoplasmic-reticulum-associated degradation (ERAD)quality control system tomanagethe production of triterpene saponins, widespread bioactive compounds that share a biogenic origin with sterols. An ERAD-type RING membraneanchor E3 ubiquitin ligase is co-expressed with saponin synthesis enzymes to control the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the rate-limiting enzyme in the supply of the ubiquitous terpene precursor isopentenyl diphosphate. Thus, unrestrained bioactive saponin accumulationis prevented and plant development and integrity secured. This control apparatus is equivalent to the ERAD system that regulates sterol synthesis in yeasts and mammals but that uses distinct E3 ubiquitin ligases, of the HMGR degradation 1 (HRD1) type, to direct destruction of HMGR. Hence, the general principles for the management of sterol and triterpene saponin biosynthesis are conserved across eukaryotes but can be controlled by divergent regulatory cues.

Der Baum in der Gegenwartskunst: Nachhaltigkeitsindikator

[deu]Dieser Artikel analysiert wie der Baum, hauptsächlich als lebendiges Wesen, im Bereich der zeitgenössischen Kunst verwendet wird. Der Baum wird als Objekt und als Subjekt behandelt, wird jedoch auch zum Experimentier- und Forschungsfeld der Kunst. Abgesehen von seinem Wesen als Objekt und Pflanze, erlangt er gleichzeitig als Standort eine räumliche Bedeutung. Anhand ausgewählter Beispiele wird aufgezeigt wie der Baum als weltweite Ikone sowohl auf die Zerstörung der Umwelt als auch auf die Ökologische Erhaltung und Zerstörung des Planeten in der zeitgenössischen Kunst hinweist.[eng]This paper analyses how the tree, mainly as a living being, is used in contemporary art. The tree is approached as object and subject, but also becomes a territory-space of experimentation and research. But beyond its plant and objectual character, the tree itself adopts a territorial sense as place. The diverse examples selected corroborate the use of the tree in contemporary art as a universal global icon of conservation and the environmental destruction of the planet.

Gelatinase expression and proteolytic activity in giant-cell arteritis

Objectives: Gelatinases (MMP2 and MMP9) are expressed in giant-cell arteritis (GCA) and are thought to play a role in vessel disruption. However, their activation status and enzymatic activity have not been evaluated. Our aim was to investigate the distribution and proteolytic activity of gelatinases in GCA lesions at different stages. Methods: Expression of MMP2, MMP9, MMP2-activator MMP14 and their natural inhibitors TIMP1 and TIMP2 was determined by real-time PCR and immunohistochemistry in temporal artery sections from 46 patients and 12 controls. MMP activation status and enzymatic activity were assessed by gelatin and film in situ zymography. Results: Vascular smooth muscle cells from normal specimens constitutively expressed pro-MMP2 and its inhibitor TIMP2 with no resulting proteolytic activity. In GCA MMP2, MMP9 and MMP14 were strongly expressed in their active form by infiltrating leucocytes. Inflamed arteries also expressed TIMP1 and TIMP2. However, the MMP9/TIMP1 and MMP2/TIMP2 ratios were higher in patients compared with controls, indicating an increased proteolytic balance in GCA which was confirmed by in situ zymography. Maximal gelatinase expression and activity occurred at the granulomatous areas surrounding the internal elastic lamina (IEL). Myointimal cells also expressed MMPs and exhibited proteolytic activity, suggesting a role for gelatinases in vascular remodelling and repair. Conclusions: GCA lesions show intense expression of gelatinases. Activators and inhibitors are regulated to yield enhanced gelatinase activation and proteolytic activity. Distribution of expression and proteolytic activity suggests that gelatinases have a major role not only in the progression of inflammatory infiltrates and vessel destruction but also in vessel repair.

Lepromatous leprosy: a review and case report

Leprosy is a contagious and chronic systemic granulomatous disease caused by Mycobacterium leprae (Hansen"s bacillus). It is transmitted from person to person and has a long incubation period (between two and six years). The disease presents polar clinical forms (the"multibacillary" lepromatous leprosy and the"paucibacillary" tuberculoid leprosy), as well as other intermediate forms with hybrid characteristics. Oral manifestations usually appear in lepromatous leprosy and occur in 20-60% of cases. They may take the form of multiple nodules (lepromas) that progress to necrosis and ulceration. The ulcers are slow to heal, and produce atrophic scarring or even tissue destruction. The lesions are usually located on the hard and soft palate, in the uvula, on the underside of the tongue, and on the lips and gums. There may also be destruction of the anterior maxilla and loss of teeth. The diagnosis, based on clinical suspicion, is confirmed through bacteriological and histopathological analyses, as well as by means of the lepromin test (intradermal reaction that is usually negative in lepromatous leprosy form and positive in the tuberculoid form). The differential diagnosis includes systemic lupus erythematosus, sarcoidosis, cutaneous leishmaniasis and other skin diseases, tertiary syphilis, lymphomas, systemic mycosis, traumatic lesions and malignant neoplasias, among other disorders. Treatment is difficult as it must be continued for long periods, requires several drugs with adverse effects and proves very expensive, particularly for less developed countries. The most commonly used drugs are dapsone, rifampicin and clofazimine. Quinolones, such as ofloxacin and pefloxacin, as well as some macrolides, such as clarithromycin and minocyclin, are also effective. The present case report describes a patient with lepromatous leprosy acquired within a contagious family setting during childhood and adolescence

La Layetania interior : estudio arqueomorfológico en un área urbana (Vallès, Barcelona). Aspectos metodológicos

Landscape research in urban or peri-urban areas implies important methodological constraints. In this sense, the area of study, placed in the Vallès basin, near the city of Barcelona, has known an important process of urbanization in the last two decades. This fact restrains the retrieving of archaeological data and the development of archaeological surveys and field-walking. The particular topography of the area must also be taken into account. It is characterised by soft slopes resulting from a differentiated seasonal rainfall. Archaeomorphological analysis has been therefore reconsidered in order to adapt its methods and techniques to this particular environment. The destruction of large agrarian areas implies that landscape morphology research must focus on an intensive work through historical cartography and old aerial photography within a gis environment. The article presents the results of the archaeological research developed in this area. The methodological approach previously exposed and the diversity of sources analysed has allowed us to characterize the ancient road network and to identify field systems from different periods.

Free Open Source Software and Dual-Use: Loophole or Dissent?

The Free Open Source Software (FOSS) seem far from the military field but in some cases, some technologies normally used for civilian purposes may have military applications. These products and technologies are called dual-use. Can we manage to combine FOSS and dual-use products? On one hand, we have to admit that this kind of association exists - dual-use software can be FOSS and many examples demonstrate this duality - but on the other hand, dual-use software available under free licenses lead us to ask many questions. For example, the dual-use export control laws aimed at stemming the proliferation of weapons of mass destruction. Dual-use export in United States (ITAR) and Europe (regulation 428/2009) implies as a consequence the prohibition or regulation of software exportation, involving the closing of source code. Therefore, the issues of exported softwares released under free licenses arises. If software are dual-use goods and serve for military purposes, they may represent a danger. By the rights granted to licenses to run, study, redistribute and distribute modified versions of the software, anyone can access the free dual-use software. So, the licenses themselves are not at the origin of the risk, it is actually linked to the facilitated access to source codes. Seen from this point of view, it goes against the dual-use regulation which allows states to control these technologies exportation. For this analysis, we will discuss about various legal questions and draft answers from either licenses or public policies in this respect.

Poblament i estructuració del territori a la comarca del Vallès Oriental: una proposta metodològica

Landscape research in urban or peri-urban areas implies important methodological constraints. In this sense, the area of study, placed in the Vallès basin, near the city of Barcelona, has known an important process of landscape’s transformation in the last two decades. This fact restrains the retrieving of archaeological data and the development of archaeological surveys and fieldwalking. The destruction of large agrarian areas implies that landscape morphology research must focus on an intensive work with historical cartography and old aerial photography within a GIS environment.

The Protein quality control system manages plant defence compound synthesis

Jasmonates are ubiquitous oxylipin-derived phytohormones that are essential in the regulation of many development, growth and defence processes. Across the plant kingdom, jasmonates act as elicitors of the production of bioactive secondarymetabolites that serve in defence against attackers. Knowledge of the conserved jasmonate perception and early signalling machineries is increasing, but the downstream mechanisms that regulate defence metabolism remain largely unknown. Herewe showthat, in the legumeMedicago truncatula, jasmonate recruits the endoplasmic-reticulum-associated degradation (ERAD)quality control system tomanagethe production of triterpene saponins, widespread bioactive compounds that share a biogenic origin with sterols. An ERAD-type RING membraneanchor E3 ubiquitin ligase is co-expressed with saponin synthesis enzymes to control the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the rate-limiting enzyme in the supply of the ubiquitous terpene precursor isopentenyl diphosphate. Thus, unrestrained bioactive saponin accumulationis prevented and plant development and integrity secured. This control apparatus is equivalent to the ERAD system that regulates sterol synthesis in yeasts and mammals but that uses distinct E3 ubiquitin ligases, of the HMGR degradation 1 (HRD1) type, to direct destruction of HMGR. Hence, the general principles for the management of sterol and triterpene saponin biosynthesis are conserved across eukaryotes but can be controlled by divergent regulatory cues.

The Protein quality control system manages plant defence compound synthesis

Jasmonates are ubiquitous oxylipin-derived phytohormones that are essential in the regulation of many development, growth and defence processes. Across the plant kingdom, jasmonates act as elicitors of the production of bioactive secondarymetabolites that serve in defence against attackers. Knowledge of the conserved jasmonate perception and early signalling machineries is increasing, but the downstream mechanisms that regulate defence metabolism remain largely unknown. Herewe showthat, in the legumeMedicago truncatula, jasmonate recruits the endoplasmic-reticulum-associated degradation (ERAD)quality control system tomanagethe production of triterpene saponins, widespread bioactive compounds that share a biogenic origin with sterols. An ERAD-type RING membraneanchor E3 ubiquitin ligase is co-expressed with saponin synthesis enzymes to control the activity of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the rate-limiting enzyme in the supply of the ubiquitous terpene precursor isopentenyl diphosphate. Thus, unrestrained bioactive saponin accumulationis prevented and plant development and integrity secured. This control apparatus is equivalent to the ERAD system that regulates sterol synthesis in yeasts and mammals but that uses distinct E3 ubiquitin ligases, of the HMGR degradation 1 (HRD1) type, to direct destruction of HMGR. Hence, the general principles for the management of sterol and triterpene saponin biosynthesis are conserved across eukaryotes but can be controlled by divergent regulatory cues.