25 resultados para implicit function theorem


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Business History, Vol 50 No 2, p147-162

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The thesis is divided into two parts corresponding to structural studies on two different proteins. The first part concerns the study of two UDP-glucose dehydrogenases (UGDs) from Sphingomonas elodea ATCC 31461 and Burkholderia cepacia IST 408, both involved in exopolysaccharide production. Their relevance arises because some of these bacterial exopolysaccharides are valuable as established biotechnological products, the former case, whilst others are highly problematic, when used by pathogens in biofilm formation over biological surfaces, as the latter case, namely in the human lungs. The goal of these studies is to increase our knowledge regarding UGDs structural properties, which can potentiate either the design of activity enhancers to respond to the increased demand of useful biofilms, or the design of inhibitors of biofilm production, in order to fight invading pathogens present in several infections. The thesis reports the production and crystallisation of both proteins, the determination of initial phases by single-wavelength anomalous dispersion (SAD) in S. elodea crystals using a seleno-methionine isoform, and phasing of B. cepacia crystals by molecular replacement (MR) using the S. elodea model, as well as the refinement, structural analysis and comparison between the several UGDs structures available during this work.(...)

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Riscos Industriais e Emergentes, 2009 pp. 827-844

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the PhD degree in Biochemistry at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the Ph.D degree in Biology

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertação para obtenção do Grau de Mestre em Engenharia e Gestão Industrial

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the Ph.D degree in Biochemistry

Relevância:

20.00% 20.00%

Publicador:

Resumo:

A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the Ph.D degree in Biology

Relevância:

20.00% 20.00%

Publicador:

Resumo:

We characterize the optimal job design in a multitasking environment when the firms rely on implicit incentive contracts (i.e., bonus payments). Two natural forms of job design are compared: (i) individual accountability, where each agent is assigned to a particular job and assumes full responsibility for its outcome; and (ii) team accountability, where a group of agents share responsibility for a job and are jointly accountable for its outcome. The key trade-off is that team accountability mitigates the multitasking problem but may weaken the implicit contracts. The optimal job design follows a cut-off rule: firms with high reputation concerns opt for team accountability, whereas firms with low reputation concerns opt for individual accountability. Team accountability is more likely the more acute the multitasking problem is. However, the cut-off rule need not hold if the firm combines implicit incentives with explicit pay-per-performance contracts.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the Ph.D degree in Biochemistry, Structural Biochemistry

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Dissertation presented to obtain the Ph.D degree in Biology, Microbial Biology