5 resultados para Graph-Based Metrics


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Dissertação apresentada para a obtenção do Grau de Doutor em Informática pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia

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Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Engenharia Electrotécnica e de Computadores

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Dissertation submitted in partial fulfillment of the requirements for the Degree of Master of Science in Geospatial Technologies.

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Dissertação submetida para a obtenção do grau de Doutor em Engenharia Electrotécnica e de Computadores

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Structural connectivity models based on Diffusion Tensor Imaging (DTI) are strongly affected by the technique’s inability to resolve crossing fibres, either intra- or inter-hemispherical connections. Several models have been proposed to address this issue, including an algorithm aiming to resolve crossing fibres which is based on Diffusion Kurtosis Imaging (DKI). This technique is clinically feasible, even when multi-band acquisitions are not available, and compatible with multi-shell acquisition schemes. DKI is an extension of DTI enabling the estimation of diffusion tensor and diffusion kurtosis metrics. In this study we compare the performance of DKI and DTI in performing structural brain connectivity. Six healthy subjects were recruited, aged between 25 and 35 (three females). The MRI experiments were performed using a 3T Siemens Trio with a 32-channel head coil. The scans included a T1-weighted sequence (1mm3), and a DWI with b-values 0, 1000 and 2000 s:mm