5 resultados para Interleukin 12
em Instituto Politécnico do Porto, Portugal
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Revista Fiscal Julho-Agosto 2006
Resumo:
Trabalho de natureza profissional para a atribuição do Título de Especialista do Instituto Politécnico do Porto, na área de Direito, defendido a 11-01-2013.
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We present a 12*(1+|R|/(4m))-speed algorithm for scheduling constrained-deadline sporadic real-time tasks on a multiprocessor comprising m processors where a task may request one of |R| sequentially-reusable shared resources.
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O conhecimento das causas dos incêndios florestais, e dos respetivos fatores de ignição, é indispensável para a eficaz implementação de medidas que visem a prevenção da sua ocorrência. Com o presente trabalho pretende-se analisar, à escala do município, a distribuição espacial das principais causas que, entre 2001 e 2012, estiveram na origem das ignições e detetar inter-relações entre as caraterísticas, físicas e humanas, dos territórios municipais e a incidência de determinado tipo de ignição.
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Recent changes in regulatory requirements and social views on animal testing have incremented the development of reliable alternative tests for predicting skin and ocular irritation potential of products based on new raw materials. In this regard, botanical ingredients used in cosmetic products are among those materials, and should be carefully reviewed concerning the potential presence of irritant constituents. In particular, cosmetic products used on the face, in vicinity of the eyes or that may come in contact with mucous membranes, should avoid botanical ingredients that contain, or are suspected to contain, such ingredients. In this study, we aimed to evaluate the effect of a new cosmetic ingredient, namely, coffee silverskin (CS), with an in vitro skin and ocular irritation assay using reconstructed human epidermis, EpiSkin™, and human corneal epithelial model, SkinEthics™ HCE, and an in vivo assay. Three different extracts of CS were evaluated. The histology of the models after extracts applications was analysed. The in vitro results demonstrated that extracts were not classified as irritant and the histological analyses proved that extracts did not affect both models structure. The content of caffeine, 5-hydroxymethyl furfural and chlorogenic acid was quantified after the epidermal assay. The in vivo test carried out with the most promising extract (hydroalcoholic) showed that, with respect to irritant effects, these extracts can be regarded as safe for topical application.