Exposição a partículas e eventuais efeitos sobre a saúde

Mestrado em Segurança e Higiene do Trabalho.

Analysis of functionally graded sandwich plate structures with piezoelectric skins, using B-spline finite strip method

Functionally graded materials are composite materials wherein the composition of the constituent phases can vary in a smooth continuous way with a gradation which is function of its spatial coordinates. This characteristic proves to be an important issue as it can minimize abrupt variations of the material properties which are usually responsible for localized high values of stresses, and simultaneously providing an effective thermal barrier in specific applications. In the present work, it is studied the static and free vibration behaviour of functionally graded sandwich plate type structures, using B-spline finite strip element models based on different shear deformation theories. The effective properties of functionally graded materials are estimated according to Mori-Tanaka homogenization scheme. These sandwich structures can also consider the existence of outer skins of piezoelectric materials, thus achieving them adaptive characteristics. The performance of the models, are illustrated through a set of test cases. (C) 2012 Elsevier Ltd. All rights reserved.

Optimal design for active damping in sandwich structures using the Direct MultiSearch method

This paper addresses the problem of optimal positioning of surface bonded piezoelectric patches in sandwich plates with viscoelastic core and laminated face layers. The objective is to maximize a set of modal loss factors for a given frequency range using multiobjective topology optimization. Active damping is introduced through co-located negative velocity feedback control. The multiobjective topology optimization problem is solved using the Direct MultiSearch Method. An application to a simply supported sandwich plate is presented with results for the maximization of the first six modal loss factors. The influence of the finite element mesh is analyzed and the results are, to some extent, compared with those obtained using alternative single objective optimization. (C) 2013 Elsevier Ltd. All rights reserved.

Adaptive mutations in bacteria: high rate and small effects

Evolution by natural selection is driven by the continuous generation of adaptive mutations. We measured the genomic mutation rate that generates beneficial mutations and their effects on fitness in Escherichia coli under conditions in which the effect of competition between lineages carrying different beneficial mutations is minimized. We found a rate on the order of 10–5 per genome per generation, which is 1000 times as high as previous estimates, and a mean selective advantage of 1%. Such a high rate of adaptive evolution has implications for the evolution of antibiotic resistance and pathogenicity.

Práticas de inclusão com alunos com multideficiência no 1º Ciclo

Dissertação apresentada à Escola Superior de Educação de Lisboa para obtenção de grau de mestre em Ciências da Educação, especialidade Educação Especial – Problemas Cognitivos e Multideficiência

Infotainment - interesse público vs interesse do público: estudo de caso das médias e grandes reportagens da SIC

Relatório de estágio apresentado à Escola Superior de Comunicação Social como parte dos requisitos para obtenção de grau de mestre em Jornalismo.

Projeto de estrutura variante de um edifício de escritórios em Lisboa

Trabalho de Projecto para obtenção do grau de Mestre em Engenharia Civil na Área de Especialização de Estruturas

Acuidade de eletrocardiograma no diagnóstico de hipertrofia ventricular esquerda em indivíduos hipertensos no distrito de Portalegre

Mestrado em Gestão e Avaliação de Tecnologias em Saúde.

Development of TNBS-induced colitis: animal model to test new pharmacological approaches

IBD is a gastro-intestinal disorder marked with chronic inflammation of intestinal epithelium, damaging mucosal tissue and manifests into several intestinal and extra-intestinal symptoms. Currently used medical therapy is able to induce and maintain the patient in remission, however no modifies or reverses the underlying pathogenic mechanism. The research of other medical approaches is crucial to the treatment of IBD and, for this, it´s important to use animal models to mimic the characteristics of disease in real life. The aim of the study is to develop an animal model of TNBS-induced colitis to test new pharmacological approaches. TNBS was instilled intracolonic single dose as described by Morris et al. It was administered 2,5% TNBS in 50% ethanol through a catheter carefully inserted into the colon. Mice were kept in a Tredelenburg position to avoid reflux. On day 4 and 7, the animals were sacrificed by cervical dislocation. The induction was confirmed based on clinical symptoms/signs, ALP determination and histopathological analysis. At day 4, TNBS group presented a decreased body weight and an alteration of intestinal motility characterized by diarrhea, severe edema of the anus and moderate morbidity, while in the two control groups weren’t identified any alteration on the clinical symptoms/signs with an increase of the body weight. TNBS group presented the highest concentrations of ALP comparing with control groups. The histopathology analysis revealed severe necrosis of the mucosa with widespread necrosis of the intestinal glands. Severe hemorrhagic and purulent exsudates were observed in the submucosa, muscular and serosa. TNBS group presented clinical symptoms/signs and histopathological features compatible with a correct induction of UC. The peak of manifestations became maximal at day 4 after induction. This study allows concluding that it’s possible to develop a TNBS induced colitis 4 days after instillation.

Toxicological Assessment of Coated versus Uncoated Rubber Granulates Obtained from Used Tires for Use in Sport Facilities

Reuse of tire crumb in sport facilities is currently a very cost-effective waste management measure. Considering that incorporation of the waste materials in artificial turf would be facilitated if the rubber materials were already colored green, coatings were specifically developed for this purpose. This paper presents an experimental toxicological and environmental assessment aimed at comparing the obtained emissions to the environment in terms of polycyclic aromatic hydrocarbons (PAHs), heavy metals, and ecotoxicity for coated and noncoated rubber granulates. This study is a comprehensive evaluation of the major potential critical factors related with the release of all of these classes of pollutants because previous studies were not systematically performed. It was concluded that between the two types of coatings tested, one is particularly effective in reducing emissions to the environment, simultaneously meeting the requirements of adherence and color stability.

Uma análise das diferenças em termos da cultura e dos interesses profissionais a partir do projeto de substituiçao das IAS 39: Financial Instruments - Recognition and Measurement

Mestrado em Contabilidade

Relatório de estágio em reabilitação da dor lombar crónica

Mestrado em Fisioterapia

Projecto de fundações e estrutura de um edifício de habitação utilizando os eurocódigos estruturais

Trabalho de Projecto para obtenção do grau de Mestre em Engenharia Civil Perfil Estruturas

José Manuel Pedroso da Silva: um original criador de ex-libris

A obra como criador de ex-libris do português José Manuel Pedroso da Silva importante investigador e criador de Heráldica.

Relatório de estágio: aulas de grupo de oboé

I (Prática Pedagógica) - Neste relatório de estágio apresenta-se uma caracterização do Conservatório de Música de Santarém (CMS). Dá-se a conhecer um pouco da sua história, o seu funcionamento e os seus objetivos pedagógicos. Caracterizam-se também os alunos que participam no estágio e faz-se uma pequena descrição dos seus percursos académicos; suas influências, motivações e expectativas. Nas práticas desenvolvidas apresentam-se os princípios pedagógicos – A Motivação, como condição fundamental para o sucesso escolar dos alunos; e ainda a importância da aquisição de competências metacognitivas, ao permitirem a reflexão sobre os processos de aprendizagem. É feita uma descrição sobre as estratégias que o professor deve adotar com o objetivo de obter a motivação dos alunos; e apresentam-se os objetivos pedagógicos propostos para este estágio. Por último é feita uma análise do trabalho desenvolvido com os alunos e uma análise crítica da atividade docente, onde a criatividade, a autoavaliação e a reflexão devem estar sempre presentes no íntimo do professor. Ainda no encerramento da secção pedagógica dá-se conta do novo paradigma do ensino vocacional de música, após a Portaria nº 691/2009 de 25 de junho, e a necessidade do professor se adaptar a esta nova realidade.