Anti-adherent and antifungal activities of surfactant-coated poly (ethylcyanoacrylate) nanoparticles

Application of non-drug-loaded poly(ethylcyanoacrylate) nanoparticles (NP) to buccal epithelial cells (BEC) imparted both anti-adherent and antifungal effects. NP prepared using emulsion polymerisation and stabilised using cationic, anionic and non-ionic surfactants decreased Candida albicans blastospore adhesion, an effect attributable to the peripheral coating of surfactant. Cetrimide and Pluronic (R) P 123 were shown to be most effective, producing mean percentage reductions in blastospore adherence of 52.7 and 37.0, respectively. Resultant zeta potential matched the polarity of the surfactant, with those stabilised using cetrimide being especially positive (+31.3 mV). Preparation using anionic surfactants was shown to be problematic, with low yield and wide particle size distribution. Evaluation of the antifungal effect of the peripheral coat was evaluated using zones of inhibition and viable counts assays. The former test revealed poor surfactant diffusion through agar, but did show evidence of limited kill. However, the latter method showed that cationic surfactants associated with NP produced high levels of kill, in contrast to those coated with anionic surfactants, where kill was not evident. Non-ionic surfactant-coated NP produced intermediate kill rates. Results demonstrate that surfactant-coated NP, particularly the cationic types, form the possible basis of a prophylactic formulation that primes the candidal target (BEC) against fungal adhesion and infection. (c) 2007 Elsevier B.V. All rights reserved.

Vortex entanglement in Bose-Einstein condensates coupled to Laguerre-Gauss beams

We study the establishment of vortex entanglement in remote Bose-Einstein condensates (BECs). We consider a two-mode photonic resource entangled in its orbital angular momentum (OAM) degree of freedom and, by exploiting the process of light-to-BEC OAM transfer, demonstrate that such entanglement can be efficiently passed to the matterlike systems. Our proposal thus represents a building block for novel dissipation-free and long-memory communication channels based on OAM. We discuss issues of practical realizability, stressing the feasibility of our scheme, and present an operative technique for the indirect inference of the set vortex entanglement.

Unusual decoherence in qubit measurements with a Bose-Einstein condensate

We consider an electrostatic qubit located near a Bose-Einstein condensate (BEC) of noninteracting bosons in a double-well potential, which is used for qubit measurements. Tracing out the BEC variables we obtain a simple analytical expression for the qubit's density matrix. The qubit's evolution exhibits a slow (proportional to 1/root t) damping of the qubit's coherence term, which however turns to be a Gaussian one in the case of static qubit. This is in contrast to the exponential damping produced by most classical detectors. The decoherence is, in general, incomplete and strongly depends on the initial state of the qubit.

Entanglement detection in hybrid optomechanical systems

We study a device formed by a Bose-Einstein condensate (BEC) coupled to the field of a cavity with a moving end mirror and find a working point such that the mirror-light entanglement is reproduced by the BEC-light quantum correlations. This provides an experimentally viable tool for inferring mirror-light entanglement with only a limited set of assumptions. We prove the existence of tripartite entanglement in the hybrid device, persisting up to temperatures of a few milli-Kelvin, and discuss a scheme to detect it.

Prospects for ultracold carbon via charge exchange reactions and laser cooled carbides

Strategies to produce an ultracold sample of carbon atoms are explored and assessed with the help of quantum chemistry. After a brief discussion of the experimental difficulties using conventional methods, two strategies are investigated. The first attempts to exploit charge exchange reactions between ultracold metal atoms and sympathetically cooled C+ ions. Ab initio calculations including electron correlation have been conducted on the molecular ions [LiC]+ and [BeC]+ to determine whether alkali or alkaline earth metals are a suitable buffer gas for the formation of C atoms but strong spontaneous radiative charge exchange ensure they are not ideal. The second technique involves the stimulated production of ultracold C atoms from a gas of laser cooled carbides. Calculations on LiC suggest that the alkali carbides are not suitable but the CH radical is a possible laser cooling candidate thanks to very favourable Frank-Condon factors. A scheme based on a four pulse STIRAP excitation pathway to a Feshbach resonance is outlined for the production of atomic fragments with near zero centre of mass velocity.

PRELIMINARY INVESTIGATIONS CONCERNING THE ANTI-ADHERENCE PROPERTIES OF POLYHEXAMETHYLENEBIGUANIDE (VANTOCIL IB(TM))

The effect of polyhexamethylenebiguanide (PHMB) on adherence of Candida albicans blastospores to human buccal epithelial cells (BEG) was examined in vitro. Treatments of either blastospores or BEC with PHMB (50 and 1000 mu g ml(-1)) significantly reduced the number of adherent blastospores per BEC and increased the number of BEC devoid of blastospores.

Probing mechanical quantum coherence with an ultracold-atom meter

We propose a scheme to probe quantum coherence in the state of a nanocantilever based on its magnetic coupling (mediated by a magnetic tip) with a spinor Bose Einstein condensate (BEC). By mapping the BEC into a rotor, its coupling with the cantilever results in a gyroscopic motion whose properties depend on the state of the cantilever: the dynamics of one of the components of the rotor angular momentum turns out to be strictly related to the presence of quantum coherence in the state of the cantilever. We also suggest a detection scheme relying on Faraday rotation, which produces only a very small back-action on the BEC and is thus suitable for a continuous detection of the cantilever's dynamics.

Progress, challenges and perspectives in positron physics:Report on the XIIth international positron workshop

A report is presented of the XIIth International Workshop on Positron and Positronium Physics (Sandbjerg, Denmark, 19-21 July 2003). This workshop covered positron and positronium interactions with atoms, molecules and condensed matter systems. One key development reported was the first creation in the laboratory of low-energy antihydrogen atoms. Facets of positron-electron many-body systems were also considered, including the positronium molecule and BEC gases of positronium atoms. Aspects of the future of the field were discussed, including the development of new theoretical and experimental capabilities.

Robust non-Markovianity in ultracold gases

We study the effect of thermal fluctuations on a probe qubit interacting with a Bose–Einstein condensed (BEC) reservoir. The zero-temperature case was studied in our previous work (Haikka et al 2011 Phys. Rev. A 84 031602), where we proposed a method for probing the effects of dimensionality and scattering length of a BEC based on its behavior as an environment. In this paper, we show that the sensitivity of the probe qubit is remarkably robust against thermal noise. We give an intuitive explanation for the thermal resilience, showing that it is due to the unique choice of the probe qubit architecture of our model.

Entanglement control via reservoir engineering in ultracold atomic gases

We study the entanglement of two impurity qubits immersed in a Bose-Einstein condensate (BEC) reservoir. This open quantum system model allows for interpolation between a common dephasing scenario and an independent dephasing scenario by modifying the wavelength of the superlattice superposed to the BEC, and how this influences the dynamical properties of the impurities. We demonstrate the existence of rich dynamics corresponding to different values of reservoir parameters, including phenomena such as entanglement trapping, revivals of entanglement, and entanglement generation. In the spirit of reservoir engineering, we present the optimal BEC parameters for entanglement generation and trapping, showing the key role of the ultracold-gas interactions. Copyright (C) EPLA, 2013

Cavity-aided quantum parameter estimation in a bosonic double-well Josephson junction

We describe an apparatus designed to make non-demolition measurements on a Bose-Einstein condensate (BEC) trapped in a double-well optical cavity. This apparatus contains, as well as the bosonic gas and the trap, an optical cavity. We show how the interaction between the light and the atoms, under appropriate conditions, can allow for a weakly disturbing yet highly precise measurement of the population imbalance between the two wells and its variance. We show that the setting is well suited for the implementation of quantum-limited estimation strategies for the inference of the key parameters defining the evolution of the atomic system and based on measurements performed on the cavity field. This would enable {\it de facto} Hamiltonian diagnosis via a highly controllable quantum probe.

Production of ultracold hydrogen and deuterium via Doppler-cooled Feshbach molecules

A counterintuitive scheme to produce ultracold hydrogen via fragmentation of laser cooled diatomic hydrides is presented where the final atomic H temperature is inversely proportional to the mass of the molecular parent. In addition, the critical density for formation of a Bose-Einstein condensate (BEC) at a fixed temperature is reduced by a factor (mH/mMH)3/2 over directly cooled hydrogen atoms. The narrow Feshbach resonances between a S01 atom and hydrogen are well suited to a tiny center of mass energy release necessary during fragmentation. With the support of ab initio quantum chemistry, it is demonstrated that BaH is an ideal diatomic precursor that can be laser cooled to a Doppler temperature of ∼26μK with just two rovibronic transitions, the simplest molecular cooling scheme identified to date. Preparation of a hydrogen atom gas below the critical BEC temperature Tc is feasible with present cooling technology, with optical pulse control of the condensation process.