New cytogenetic aberrations found in a case of aggressive retinoblastoma

We describe a case of retinoblastoma with an atypical presentation and previously unreported cytogenetic aberrations. A 19-month-old girl with left intraocular retinoblastoma was treated with enucleation and chemotherapy. The disease showed aggressive evolution within a short period between diagnosis and relapse. Eight months after diagnosis, a new large tumor was present in the orbit of the right eye, with diffuse bone pain, pancytopenia and diffuse infiltration into the bone marrow and the central nervous system. The child did not respond to treatment and died. Cytogenetic studies made with G-banding, FISH and SKY analysis showed chromosomal aberrations commonly associated with retinoblastoma, including del(13q), i(6+1, and monosomy 16, along with others that had not been reported previously, including dup(5q), dic(15;22) and add(14q). The new chromosomal aberrations may be related to the aggressiveness of the disease in this case.

Magnetophotoluminescence study of GaAs/AlGaAs coupled double quantum wells with bimodal heterointerface roughness

This work reports on the results of magnetophotoluminescence (MPL) measurements carried out in a sample containing two Al0.35Ga0.65As/GaAs, coupled double quantum wells (CDQWs), with inter-well barriers of different thicknesses, which have the heterointerfaces characterized by a distribution of bimodal roughness. The MPL measurements were performed at 4 K, with magnetic fields applied parallel to the growth direction, and varying from 0 to 12 T. The diamagnetic shift of the photoluminescence (PL) peaks is more sensitive to changes in the confinement potential, due to monolayer variations in the mini-well thickness, rather than to the exciton localization at the local potential fluctuations. As the magnetic field increases, the relative intensities of the two peaks in each PL band inverts, what is attributed to the reduction in the radiative lifetime of the delocalized excitons, which results in the radiative recombination, before the excitonic migration between the higher and lower energy regions in each CDQW occurs. The dependence of the full width at half maximum (FWHM) on magnetic field shows different behaviors for each PL peak, which are attributed to the different levels and correlation lengths of the potential fluctuations present in the regions associated with each recombination channel. (C) 2011 Elsevier B.V. All rights reserved.

Essays on the history of Brazilian dipterology: II. notices about Brazilian Diptera (17th century)

Essays on the history of Brazilian dipterology. II. Notices about Brazilian Diptera (17th century). Notices from the Brazilian Diptera from the 17th century come mainly from two foreign invasions occurred in Brazil, the first one by the French in Maranhão and the second by the Dutch in northeastern Brazil. This paper includes reports of Fathers Claude d'Abbeville and Yves d'Evreux and from Piso and Marcgrave, the last two presenting the first illustrations of Brazilian Diptera. The paper also includes reports of Friar Laureano de la Cruz, Father João de Sotto Mayor and Maurício de Heriarte.

Essays on the history of brazilian dipterology: III. Three remarkable notices from the 18th century, mainly related to myiasis-producing flies (Cochliomyia and Dermatobia)

This paper registers reports about dipterans made by three Portuguese who lived in Brazil during the 18th century. Luiz Gomes Ferreira, in his book "Erário mineral" ["Mineral revenue"], wrote curious passages related with myiasis-causing flies of the genus Cochliomyia. José Rodrigues de Mello registered, in Latin verses, the folklore for curing myiases caused by Cochliomyia hominivorax in cattle. Luiz dos Santos Vilhena, in the last of his twenty letters dealing with several aspects of life in Brazil, made reference to horseflies, human bot flies and mosquitos.

De Anita à acadêmia: para repensar a história da arte no Brasil

A partir de uma citação do romance Mocidade morta, de Gonzaga-Duque, e da análise de algumas pinturas brasileiras, produzidas entre a segunda metade do século XIX e a primeira do século XX, este texto problematiza alguns paradigmas da história da arte no Brasil. Enfatiza a necessidade de rever a periodização da arte brasileira, uma vez que as diferenças entre produções "acadêmicas" e outras "modernistas" parecem apenas tópicas

História e memória do ensino de física no Brasil: a faculdade de medicina de São Paulo (1913-1943)

Este trabalho apresenta um recorte histórico do ensino de Física na Faculdade de Medicina de São Paulo no período de 1913 a 1943. Vimos que o curso superior de Física foi essencial no remodelamento curricular da Física secundária. Destacamos a seleção cultural escolar por meio dos livros didáticos, apontando para aqueles que influenciaram e guiaram as mudanças curriculares da instituição, cujo enfoque curricular, no ensino de Física, foi criado em virtude de uma necessidade social. Mergulhamos nas práticas escolares por meio das relações microscópicas entre o que se estudava e que encontramos materializado nas avaliações do conteúdo de Física. Dessa forma, expusemos tradições pedagógicas, procedimentos e condutas sobre o cotidiano escolar da instituição que visavam aprimorar o ensino de Física. Assim, as questões e exercícios das provas analisadas, foram necessidades pedagógicas criadas dentro e para a escola, que não são constantes e uniformes, uma vez que dependem da sociedade, do público escolar e das matérias.