31 resultados para HIGH-DENSITY-LIPOPROTEIN
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- Aberdeen University (3)
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- AMS Tesi di Laurea - Alm@DL - Università di Bologna (1)
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- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (31)
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- Chinese Academy of Sciences Institutional Repositories Grid Portal (72)
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- Deakin Research Online - Australia (40)
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- Digital Commons at Florida International University (8)
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- DRUM (Digital Repository at the University of Maryland) (2)
- Duke University (4)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (6)
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- Helda - Digital Repository of University of Helsinki (18)
- Indian Institute of Science - Bangalore - Índia (20)
- INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES (IPEN) - Repositório Digital da Produção Técnico Científica - BibliotecaTerezine Arantes Ferra (1)
- Instituto Nacional de Saúde de Portugal (2)
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- Massachusetts Institute of Technology (1)
- National Center for Biotechnology Information - NCBI (57)
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- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (114)
- Queensland University of Technology - ePrints Archive (92)
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- Repositório Institucional da Universidade Estadual de São Paulo - UNESP (1)
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- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (107)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- School of Medicine, Washington University, United States (2)
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- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (5)
- Universidad Politécnica de Madrid (5)
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- Universidade Federal do Rio Grande do Norte (UFRN) (10)
- Université de Lausanne, Switzerland (8)
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- Université de Montréal, Canada (16)
- Université Laval Mémoires et thèses électroniques (1)
- University of Michigan (4)
- University of Queensland eSpace - Australia (27)
- University of Washington (1)
- WestminsterResearch - UK (1)
Resumo:
Metabolic syndrome (MetS) is an inflammatory state associated with high coronary disease risk. Inflammation and adaptive immunity modulate atherosclerosis and plaque instability. We examined early changes in anti-oxidized lowdensity lipoprotein (LDL) (anti-oxLDL) autoantibodies (Abs) in patients with MetS after an acute coronary syndrome (ACS). Patients of both genders (n=116) with MetS were prospectively included after an acute yocardial infarction (MI) or hospitalization due to unstable angina. Anti-oxLDL Abs (IgG class) were assayed at baseline, three and six weeks after ACS. The severity of coronary disease was evaluated by the Gensini score. We observed a decrease in anti-oxLDL Abs titers (p<0.002 vs. baseline), mainly in males (p=0.01), in those under 65 y (p=0.03), and in subjects with Gensini score above median (p=0.04). In conclusion, early decrease in circulating anti-oxLDL Abs is associated with coronary disease severity among subjects with MetS.