Libertação fotocontrolada de moléculas bioativas a partir de conjugados de cumarinas

Dissertação de mestrado em Química Medicinal

Flexible organic–inorganic hybrid layer encapsulation for organic opto-electronic devices

In this work we produce and study the flexible organic–inorganic hybrid moisture barrier layers for the protection of air sensitive organic opto-electronic devices. The inorganic amorphous silicon nitride layer (SiNx:H) and the organic PMMA [poly (methyl methacrylate)] layer are deposited alternatingly by using hot wire chemical vapor deposition (HW-CVD) and spin-coating techniques, respectively. The effect of organic–inorganic hybrid interfaces is analyzed for increasing number of interfaces. We produce highly transparent (∼80% in the visible region) hybrid structures. The morphological properties are analysed providing a good basis for understanding the variation of the water vapor transmission rate (WVTR) values. A minimum WVTR of 4.5 × 10−5g/m2day is reported at the ambient atmospheric conditions for 7 organic/inorganic interfaces. The hybrid barriers show superb mechanical flexibility which confirms their high potential for flexible applications.

Hind limb ischemia in type 1 diabetic mice as useful tool to evaluate the neovascularization of tissue engineering constructs

Hind-limb ischemia has been used in type 1 diabetic mice to evaluate treatments for peripheral arterial disease or mechanisms of vascular impairment in diabetes [1]. Vascular deficiency is not only a pathophysiological condition, but also an obvious circumstance in tissue regeneration and in tissue engineering and regenerative medicine (TERM) strategies. We performed a pilot experiment of hind-limb ischemia in streptozotocin(STZ)-induced type 1 diabetic mice to hypothesise whether diabetes influences neovascularization induced by biomaterials. The dependent variables included blood flow and markers of arteriogenesis and angiogenesis. Type 1 diabetes was induced in 8-week-old C57BL/6 mice by an i.p. injection of STZ (50 mg/kg daily for 5 days). Hind-limb ischemia was created under deep anaesthesia and the left femoral artery and vein were isolated, ligated, and excised. The contralateral hind limb served as an internal control within each mouse. Non-diabetic ischaemic mice were used as experiment controls. At the hind-limb ischemia surgical procedure, different types of biomaterials were placed in the blood vessels gap. Blood flow was estimated by Laser Doppler perfusion imager, right after surgery and then weekly. After 28 days of implantation, surrounding muscle was excised and evaluated by histological analysis for arteriogenesis and angiogenesis. The results showed that implanted biomaterials were promote faster restoration of blood flow in the ischemic limbs and improved neovascularization in the diabetic mice. Therefore, we herein demonstrate that the combined model of hind-limb ischemia in type 1 diabetes mice is suitable to evaluate the neovascularization potential of biomaterials and eventually tissue engineering constructs.  

Desenvolvimento de um BMS para aplicações de mobilidade elétrica

Dissertação de mestrado integrado em Engenharia Eletrónica Industrial e de Computadores

Requalificação de uma máquina-ferramenta

Dissertação de mestrado integrado em Engenharia Mecânica

Erratum: Ureasilicate hybrid coatings for corrosion protection of galvanized steel in cementitious media

Artigo completo publicado na revista "Journal of The Electrochemical Society" 160:10 (2013) 467-479 e disponível no RepositóriUM em: http://hdl.handle.net/1822/33855

Erratum: Alcohol-aminosilicate hybrid coatings for corrosion protection of galvanized steel in mortar

Artigo completo publicado na revista "Journal of The Electrochemical Society" 161:6 (2014) C349-C362 e disponível no RepositóriUM em: http://hdl.handle.net/1822/33784

Erratum: Erratum: Alcohol-aminosilicate hybrid coatings for corrosion protection of galvanized steel in mortar

Artigo completo publicado na revista "Journal of The Electrochemical Society" 161:6 (2014) C349-C362 e disponível no RepositóriUM em: http://hdl.handle.net/1822/33784. Errata disponível no RepositóriUM em: http://hdl.handle.net/1822/40064. (Publisher’s note: An erratum that addressed the errors in Figure 9 was originally published on Dec. 10, 2014, however the graphs in that erratum were not correct.)

Experimental and numerical studies of hybrid PCM embedded in plastering mortar for enhanced thermal behaviour of buildings

This paper proposes a methodology for improvement of energy efficiency in buildings through the innovative simultaneous incorporation of three distinct phase change materials (here termed as hybrid PCM) in plastering mortars for façade walls. The thermal performance of a hybrid PCM mortar was experimentally evaluated by comparing the behaviour of a prototype test cell (including hybrid PCM plastering mortar) subjected to realistic daily temperature profiles, with the behaviour of a similar prototype test cell, in which no PCM was added. A numerical simulation model was employed (using ANSYS-FLUENT) to validate the capacity of simulating temperature evolution within the prototype containing hybrid PCM, as well as to understand the contribution of hybrid PCM to energy efficiency. Incorporation of hybrid PCM into plastering mortars was found to have the potential to significantly reduce heating/cooling temperature demands for maintaining the interior temperature within comfort levels when compared to normal mortars (without PCM), or even mortars comprising a single type of PCM.

Optimal behavior of responsive residential demand considering hybrid phase change materials

Due to communication and technology developments, residential consumers are enabled to participate in Demand Response Programs (DRPs), control their consumption and decrease their cost by using Household Energy Management (HEM) systems. On the other hand, capability of energy storage systems to improve the energy efficiency causes that employing Phase Change Materials (PCM) as thermal storage systems to be widely addressed in the building applications. In this paper, an operational model of HEM system considering the incorporation of more than one type of PCM in plastering mortars (hybrid PCM) is proposed not only to minimize the customerâ s cost in different DRPs but also to guaranty the habitantsâ  satisfaction. Moreover, the proposed model ensures the technical and economic limits of batteries and electrical appliances. Different case studies indicate that implementation of hybrid PCM in the buildings can meaningfully affect the operational pattern of HEM systems in different DRPs. The results reveal that the customerâ s electricity cost can be reduced up to 48% by utilizing the proposed model.

Avaliação da implementação do SAP ERP na logística: estudo de caso

Dissertação de mestrado em Engenharia de Sistemas

Implementação de um sistema de customer relationship management na broaden information solutions

Dissertação de mestrado em Sistemas de Informação

Moradias sobredimensionadas dos anos 70‐90 na periferia de Braga: processo de transformação

According to the latest census (2011) covering the Portuguese housing stock, there is a considerable number of sub-occupied buildings and most of them were built before the first Portuguese Thermal Code (RCCTE). In view of the objectives of the European Union (20-20-20), it is necessary to contribute to the rehabilitation of existing buildings by promoting the densification of oversized houses, while complying with up-to-date comfort standards and codes. In this sense, this research is aimed to analyse this problem at the outskirts of Braga, by identifying the type-morphology of oversized buildings, assessing the degree of satisfaction and expectations of both owners and inhabitants and developing and testing a systematic design tool. Through the development of an intervention kit, wich systematizes and priorizes design strategies and solutions, the design team can have the necessary decision-making support tool to improve the spacial design of the building whilst considering energy efficency, sustainability and improvemente of interior environmental quality.

Development of hybrid composite plate (HCP) for strengthening and repair of RC structures

Tese de Doutoramento em Engenharia Civil

Hybrid hypervisor partially deployed on FPGA

Tese de Doutoramento em Engenharia Eletrónica e Computadores.