Contribuição para equipamento didático de máquina de medição por coordenadas

Dissertação de mestrado integrado em Engenharia Mecânica

Estudo da cabeceira da Sé do Porto

Dissertação de mestrado integrado em Engenharia Civil

Diagnóstico e ensaio de carga de asnas tradicionais de madeira

Dissertação de mestrado Integrado em Engenharia Civil

A novel hanging spherical drop system for the generation of cellular spheroids and high throughput combinatorial drug screening

We propose a novel hanging spherical drop system for anchoring arrays of droplets of cell suspension based on the use of biomimetic superhydrophobic flat substrates, with controlled positional adhesion and minimum contact with a solid substrate. By facing down the platform, it was possible to generate independent spheroid bodies in a high throughput manner, in order to mimic in vivo tumour models on the lab-on-chip scale. To validate this system for drug screening purposes, the toxicity of the anti-cancer drug doxorubicin in cell spheroids was tested and compared to cells in 2D culture. The advantages presented by this platform, such as feasibility of the system and the ability to control the size uniformity of the spheroid, emphasize its potential to be used as a new low cost toolbox for high-throughput drug screening and in cell or tissue engineering.

Biomimetic superhydrophobic surfaces patterned with wettable spots as implantable chips for in vivo high-content 3D biomaterials response assessment

"Tissue engineering: part A", vol. 21, suppl. 1 (2015)

Aplicação de metodologias BIM no contexto da construção da nova ponte sobre o Rio Dão

Dissertação de mestrado integrado em Engenharia Civil

A aprendizagem de tópicos da circunferência com recurso ao GeoGebra: uma experiência com alunos do 9.º ano de escolaridade

Relatório de estágio de mestrado em Ensino de Matemática no 3.º ciclo do Ensino Básico e no Ensino Secundário

Desenvolvimento de um motor BMW para servir de Range Extender

Dissertação de mestrado integrado em Engenharia Mecânica

Avaliação do funcionamento de um motor diesel com biodiesel

Dissertação de mestrado integrado em Engenharia Mecânica

Separation by thermal diffusion in a rotary column

A rotary thermal diffusion column with the inner cylinder rotating and the outer cylinder static was used to separate n-heptane-benzene mixtures at different speeds of rotation. The results show that the column efficiency depends on the speed of rotation. For the optimum speed the increase in efficiency relative to the static column was of the order of 8%. The role of the geometric irregularities in the annulus width on performance of the rotary column is also discussed.