受冲击的饱和砂土产生裂缝和通道的实验研究

本文首先对饱和砂土在动载荷下的液化、密实和结构破坏等方面做了文献综述，同时也叙述了化工冶金中的液固流态化的有关情况。本文探讨了饱和砂土中产生水平裂缝和纵向通道等现象的机理。为此，进行了扁平砂柱的落锤冲击实验和模拟圆柱落锤冲击实验中产生水平裂缝和纵向通道等现象的底部加压实验。扁平砂柱落锤冲击实验的目的是为了更清楚地观察饱和砂土结构破坏和孔隙水流动的情况，观察纵向通道和水平裂缝的产生和发展，以及水平裂缝和纵向通道之间的联系。为了探讨水平裂缝和纵向通道产生的条件和机理，设计和进行了底部加压实验，用来模拟落锤冲击实验的后期变形和渗流效应，测量出现水平裂缝和纵向通道时的超孔隙水压力和平均水流速度，统计分析采用什么样的参数可以表征水平裂缝和纵向通道的出现及其特性，发现液化指数等于1是出现水平裂缝的必要条件。此外，针对含有细砂层的饱和砂土在该层出现水平裂缝的现象，提出了一个简化模型，推导出砂柱的液化指数一维分布，根据液化指数等于1才能出现水平裂缝，能够说明水平裂缝出现的条件和位置。

Water and salt movements in simultaneous flood-irrigation and well-drainage operations

This paper describes a new technology for solonchak soil reclamation in which surface flood irrigation of fresh water and pumped wells drainage of salty groundwater are combined. The comprehensive investigation of water and salt movement has been conducted through field test, laboratory simulation and numerical calculation. The dependence of desalination on irrigation water quantity, drainage quantity, leaching time and other parameters is obtained based on the field tests. The entire desalination process under the flood-irrigation and well-drainage operations was experimentally simulated in a vertical soil column. The water and salt movement has been numerically analysed for both the field and laboratory conditions. The present work indicates that this new technology can greatly improve the effects of desalination.

Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia

The tumor suppressor p53 is a master sensor of stress. Two human-specific polymorphisms, p53 codon 72 and MDM2 SNP309, influence the activities of p53. There is a tight association between cold winter temperature and p53 Arg72 and between low UV intensity

A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand

Recent transcription profiling studies have revealed an unexpectedly large proportion of antisense transcripts in eukaryotic genomes. These antisense genes seem to regulate gene expression by interacting with sense genes. Previous studies have focused on the non-coding antisense genes, but the possible regulatory role of the antisense protein is poorly understood. In this study, we found that a protein encoded by the antisense gene ADF1 acts as a transcription suppressor, regulating the expression of sense gene MDF1 in Saccharomyces cerevisiae. Based on the evolutionary, genetic, cytological and biochemical evidence, we show that the protein-coding sense gene MDF1 most likely originated de novo from a previously non-coding sequence and can significantly suppress the mating efficiency of baker's yeast in rich medium by binding MAT alpha 2 and thus promote vegetative growth. These results shed new light on several important issues, including a new sense-antisense interaction mechanism, the de novo origination of a functional gene, and the regulation of yeast mating pathway.

Structure Elucidation and Theoretical Investigation of Key Steps in the Biogenetic Pathway of Schisanartane Nortriterpenoids by Using DFT Methods

Rubrifloradilactone C (4), a novel bioactive nortriterpenoid, along with four other nortriterpenoids (1-3, 5) were isolated from Schisandra rubriflora. The structure of 4 was determined by extensive NMR spectral analysis, computational evidence by using t

Acute behavioural stress facilitates long-term depression in temporoammonic-CAI pathway

Behavioural stress facilitates long-term depression in Schaffer collaterals-CAI pathway, but it is unknown whether it influences long-term depression in temporoammonic fibres-CAI. Here, we report that low-frequency stimulation induced long-term depression

Opiate withdrawal modifies synaptic plasticity in subicular-nucleus accumbens pathway in vivo

Subiculum receives output of hippocampal CAI neurons and projects glutamatergic synapses onto nucleus accumbens (NAc), the subicular-NAc pathway linking memory and reward system. It is unknown whether morphine withdrawal influences synaptic plasticity in